The DOI matches its Crossref record; 130 of the 130 references it cites were found in a registry or an index.
Modulation of the Ryanodine Receptor and Intracellular Calcium
Abstract
Ryanodine receptors (RyRs)/Ca 2+ release channels, on the endoplasmic and sarcoplasmic reticulum of most cell types, are required for intracellular Ca 2+ release involved in diverse cellular functions, including muscle contraction and neurotransmitter release. The large cytoplasmic domain of the RyR serves as a scaffold for proteins that bind to and modulate the channel's function and that comprise a macromolecular signaling complex. These proteins include calstabins [FK506-binding proteins (FKBPs)], calmodulin (CaM), phosphodiesterase, kinases, phosphatases, and their cognate targeting proteins. This review focuses on recent progress in the understanding of RyR regulation and disease mechanisms that are associated with channel dysfunction.
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Cites
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Cited by
Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging
Andersson, D. C., Betzenhauser, M. J., Reiken, S., Meli, A. C., Umanskaya, A., Xie, W., Shiomi, T., Zalk, R., Lacampagne, A., & Marks, A. R. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.05.014 · Cited by 424
Intercellular Ca2+Waves: Mechanisms and Function
Leybaert, L., & Sanderson, M. J. (2012) · Physiological Reviews · doi:10.1152/physrev.00029.2011 · Cited by 331
Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity
Pessah, I. N., Cherednichenko, G., & Lein, P. J. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.10.009 · Cited by 231
Falcone, S., Roman, W., Hnia, K., Gache, V., Didier, N., Lainé, J., Auradé, F., Marty, I., Nishino, I., Charlet‐Berguerand, N., et al. (2014) · EMBO Molecular Medicine · doi:10.15252/emmm.201404436 · Cited by 116
Russ, D. W., Grandy, J. S., Toma, K., & Ward, C. W. (2011) · Acta Physiologica · doi:10.1111/j.1748-1716.2010.02191.x · Cited by 61
Metadata
- Authors
- Zalk, R., Lehnart, S. E., & Marks, A. R.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 2007-06-07
- Volume
- 76
- Issue
- 1
- Pages
- 367-385
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2139909390
- Cited by
- 371
- References
- 130
- FWCI
- 1.53
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zalk, R., Lehnart, S. E., & Marks, A. R. (2007). Modulation of the Ryanodine Receptor and Intracellular Calcium. Annual Review of Biochemistry. https://doi.org/10.1146/annurev.biochem.76.053105.094237
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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