Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 553

The DOI matches its Crossref record; 124 of the 124 references it cites were found in a registry or an index.

The Structural and Functional Diversity of Metabolite-Binding Riboswitches

Open access
Roth, Adam, Breaker, Ronald R.·2009·Annual Review of Biochemistry

Abstract

The cellular concentrations of certain metabolites are assiduously monitored to achieve appropriate levels of gene expression. Although proteins have long been known to act as sensors in this capacity, metabolite-binding RNAs, or riboswitches, also play an important role. More than 20 distinct classes of riboswitches have been identified to date, and insights to the molecular recognition strategies of a significant subset of these have been provided by detailed structural studies. This diverse set of metabolite-sensing RNAs is found to exploit a variety of distinct mechanisms to regulate genes that are fundamental to metabolism.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1146/annurev.biochem.78.070507.135656

Cites

124 of 124 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 124 references

Cited by

See all 553

Metadata

Authors
Roth, A., & Breaker, R. R.
Venue
Annual Review of Biochemistry
Published
2009-06-01
Volume
78
Issue
1
Pages
305-334
ISSN
  • 0066-4154 (ISSN-L)
  • 1545-4509
OpenAlex
W2157052506
Cited by
553
References
124
FWCI
2.83
Type
journal article
Language
en
Open access
green

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: The Structural and Functional Diversity of Metabolite-Binding Riboswitches. https://app.cochat.ai/papers/10.1146/annurev.biochem.78.070507.135656
The paper
Roth, A., & Breaker, R. R. (2009). The Structural and Functional Diversity of Metabolite-Binding Riboswitches. Annual Review of Biochemistry. https://doi.org/10.1146/annurev.biochem.78.070507.135656

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.