The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Chemical Exchange Saturation Transfer Contrast Agents for Magnetic Resonance Imaging
Open accessAbstract
Magnetic resonance imaging (MRI) contrast agents have become an important tool in clinical medicine. The most common agents are Gd 3+-based complexes that shorten bulk water T 1 by rapid exchange of a single inner-sphere water molecule with bulk solvent water. Current gadolinium agents lack tissue specificity and typically do not respond to their chemical environment. Recently, it has been demonstrated that MR contrast may be altered by an entirely different mechanism based on chemical exchange saturation transfer (CEST). CEST contrast can originate from exchange of endogenous amide or hydroxyl protons or from exchangeable sites on exogenous CEST agents. This has opened the door for the discovery of new classes of responsive agents ranging from MR gene reporter molecules to small molecules that sense their tissue environment and respond to biological events.
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Cites
Flacke, S., Fischer, S., Scott, M. J., Fuhrhop, R. J., Allen, J. S., McLean, M., Winter, P., Sicard, G. A., Gaffney, P. J., Wickline, S. A., et al. (2001) · Circulation · doi:10.1161/hc3601.094303 · Cited by 515
Cited by
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Wahsner, J., Gale, E. M., Rodríguez-Rodríguez, A., & Caravan, P. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00363 · Cited by 1,603
Chemical exchange saturation transfer (CEST): what is in a name and what isn't?
van Zijl, P. C. M., & Yadav, N. N. (2011) · Magnetic Resonance in Medicine · doi:10.1002/mrm.22761 · Cited by 1,155
Zhou, J., Tryggestad, E., Wen, Z., Lal, B., Zhou, T., Grossman, R., Wang, S., Yan, K., Fu, D.-X., Ford, E., et al. (2011) · Nature Medicine · doi:10.1038/nm.2268 · Cited by 526
Nanoparticles as contrast agents for in-vivo bioimaging: current status and future perspectives
Hahn, M. A., Singh, A. K., Sharma, P., Brown, S. C., & Moudgil, B. M. (2011) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-010-4207-5 · Cited by 485
The pyridyl group in ligand design for selective metal ion complexation and sensing
Hancock, R. D. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35224a · Cited by 353
Metadata
- Authors
- Sherry, A. D., & Woods, M.
- Venue
- Annual Review of Biomedical Engineering
- Publisher
- Annual Reviews
- Published
- 2008-08-01
- Volume
- 10
- Issue
- 1
- Pages
- 391-411
- ISSN
- 1523-9829 (ISSN-L)
- 1545-4274
- OpenAlex
- W2130291666
- Cited by
- 356
- References
- 1
- FWCI
- 1.87
- Type
- journal article
- Language
- en
- Open access
- green
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- Sherry, A. D., & Woods, M. (2008). Chemical Exchange Saturation Transfer Contrast Agents for Magnetic Resonance Imaging. Annual Review of Biomedical Engineering. https://doi.org/10.1146/annurev.bioeng.9.060906.151929
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
