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Cited by 346

The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.

RAMAN SPECTROSCOPY OF PROTEIN AND NUCLEIC ACID ASSEMBLIES

Thomas, George J.·1999·Annual Review of Biophysics and Biomolecular Structure

Abstract

▪ Abstract The Raman spectrum of a protein or nucleic acid consists of numerous discrete bands representing molecular normal modes of vibration and serves as a sensitive and selective fingerprint of three-dimensional structure, intermolecular interactions, and dynamics. Recent improvements in instrumentation, coupled with innovative approaches in experimental design, dramatically increase the power and scope of the method, particularly for investigations of large supramolecular assemblies. Applications are considered that involve the use of (a) time-resolved Raman spectroscopy to elucidate assembly pathways in icosahedral viruses, (b) polarized Raman microspectroscopy to determine detailed structural parameters in filamentous viruses, (c) ultraviolet-resonance Raman spectroscopy to probe selective DNA and protein residues in nucleoprotein complexes, and (d) difference Raman methods to understand mechanisms of protein/DNA recognition in gene regulatory and chromosomal complexes.

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Crossref · 10.1146/annurev.biophys.28.1.1

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Metadata

Authors
Thomas, G. J.
Venue
Annual Review of Biophysics and Biomolecular Structure
Published
1999-06
Volume
28
Issue
1
Pages
1-27
ISSN
  • 1056-8700 (ISSN-L)
  • 1545-4266
OpenAlex
W2151143141
Cited by
346
References
40
FWCI
4.72
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: RAMAN SPECTROSCOPY OF PROTEIN AND NUCLEIC ACID ASSEMBLIES. https://app.cochat.ai/papers/10.1146/annurev.biophys.28.1.1
The paper
Thomas, G. J. (1999). RAMAN SPECTROSCOPY OF PROTEIN AND NUCLEIC ACID ASSEMBLIES. Annual Review of Biophysics and Biomolecular Structure. https://doi.org/10.1146/annurev.biophys.28.1.1

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.