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Cited by 261

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Signaling and Subcellular Targeting by Membrane-Binding Domains

Open access
Hurley, James H., Misra, Saurav·2000·Annual Review of Biophysics and Biomolecular Structure

Abstract

▪ Abstract Protein kinase C homology-1 and -2, FYVE, and pleckstrin homology domains are ubiquitous in eukaryotic signal transduction and membrane-trafficking proteins. These domains regulate subcellular localization and protein function by binding to lipid ligands embedded in cell membranes. Structural and biochemical analysis of these domains has shown that their molecular mechanisms of membrane binding depend on a combination of specific and nonspecific interactions with membrane lipids. In vivo studies of green fluorescent protein fusions have highlighted the key roles of these domains in regulating protein localization to plasma and internal membranes in cells.

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Crossref · 10.1146/annurev.biophys.29.1.49

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Metadata

Authors
Hurley, J. H., & Misra, S.
Venue
Annual Review of Biophysics and Biomolecular Structure
Published
2000-06
Volume
29
Issue
1
Pages
49-79
ISSN
  • 1056-8700 (ISSN-L)
  • 1545-4266
OpenAlex
W2098851635
Cited by
261
References
7
FWCI
9.24
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Signaling and Subcellular Targeting by Membrane-Binding Domains. https://app.cochat.ai/papers/10.1146/annurev.biophys.29.1.49
The paper
Hurley, J. H., & Misra, S. (2000). Signaling and Subcellular Targeting by Membrane-Binding Domains. Annual Review of Biophysics and Biomolecular Structure. https://doi.org/10.1146/annurev.biophys.29.1.49

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.