Phospholipid-binding protein domains

Functional rafts in cell membranes

Simons, K., & Ikonen, E. (1997) · Nature · doi:10.1038/42408 · Cited by 9,757 · see citing works

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha.

Alessi, D., James, S., Downes, C., Holmes, A. B., Gaffney, P., Reese, C., & Cohen, P. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00122-9 · Cited by 3,047 · see citing works

Mechanism of activation of protein kinase B by insulin and IGF‐1.

Alessi, D. R., Andjelković, M., Caudwell, B., Cron, P. D., MORRICE, N. A., Cohen, P., & Hemmings, B. A. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb01045.x · Cited by 2,985 · see citing works

Protein modules and signalling networks

Pawson, T. (1995) · Nature · doi:10.1038/373573a0 · Cited by 2,420 · see citing works

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

Burgering, B. M. T., & Coffer, P. J. (1995) · Nature · doi:10.1038/376599a0 · Cited by 2,113 · see citing works

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Franke, T. F., Yang, S., Chan, T. O., Datta, K., Kazlauskas, A., Morrison, D. K., Kaplan, D. R., & Tsichlis, P. N. (1995) · Cell · doi:10.1016/0092-8674(95)90534-0 · Cited by 2,006 · see citing works

PI3K: Downstream AKTion Blocks Apoptosis

Franke, T. F., Kaplan, D. R., & Cantley, L. C. (1997) · Cell · doi:10.1016/s0092-8674(00)81883-8 · Cited by 1,692 · see citing works

Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

Franke, T. F., Kaplan, D., Cantley, L., & Toker, A. (1997) · Science · doi:10.1126/science.275.5300.665 · Cited by 1,609 · see citing works

Three-dimensional structure of the tyrosine kinase c-Src

Xu, W., Harrison, S. C., & Eck, M. J. (1997) · Nature · doi:10.1038/385595a0 · Cited by 1,428 · see citing works

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

Stokoe, D., Stephens, L. R., Copeland, T., Gaffney, P. R. J., Reese, C. B., Painter, G. F., Holmes, A. B., McCormick, F. P., & Hawkins, P. T. (1997) · Science · doi:10.1126/science.277.5325.567 · Cited by 1,202 · see citing works

Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

Hinshaw, J. E., & Schmid, S. L. (1995) · Nature · doi:10.1038/374190a0 · Cited by 824 · see citing works

Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

Lassing, I., & Lindberg, U. (1985) · Nature · doi:10.1038/314472a0 · Cited by 823 · see citing works

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

Perin, M. S., Fried, V. A., Mignery, G. A., Jahn, R., & Südhof, T. C. (1990) · Nature · doi:10.1038/345260a0 · Cited by 813 · see citing works

The C2 domain calcium‐binding motif: Structural and functional diversity

Nalefski, E. A., & Falke, J. (1996) · Protein Science · doi:10.1002/pro.5560051201 · Cited by 802 · see citing works

Role of Substrates and Products of PI 3-kinase in Regulating Activation of Rac-Related Guanosine Triphosphatases by Vav

Han, J., Luby‐Phelps, K., Das, B., Shu, X., Xia, Y., Mosteller, R. D., Krishna, U. M., Falck, J. R., White, M. A., & Broek, D. (1998) · Science · doi:10.1126/science.279.5350.558 · Cited by 792 · see citing works

Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

Takei, K., McPherson, P. S., Schmid, S. L., & Camilli, P. V. D. (1995) · Nature · doi:10.1038/374186a0 · Cited by 768 · see citing works

Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells

Stauffer, T. P., Ahn, S., & Meyer, T. (1998) · Current Biology · doi:10.1016/s0960-9822(98)70135-6 · Cited by 761 · see citing works

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

Harlan, J. E., Hajduk, P. J., Yoon, H. S., & Fesik, S. W. (1994) · Nature · doi:10.1038/371168a0 · Cited by 761 · see citing works

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: Crystal structures of the complexed and peptide-free forms

Waksman, G. (1993) · Cell · doi:10.1016/0092-8674(93)90405-f · Cited by 747 · see citing works

Mechanism of activation and function of protein kinase B

Alessi, D. R., & Cohen, P. (1998) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(98)80062-2 · Cited by 743 · see citing works

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

Alessi, D. R., Deák, M., Casamayor, A., Caudwell, F. B., MORRICE, N. A., Norman, D. G., Gaffney, P. R. J., Reese, C. B., MacDougall, C. N., Harbison, D., et al. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00336-8 · Cited by 737 · see citing works

Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold.

Sutton, R., Davletov, B., Berghuis, A., Südhof, T., & Sprang, S. R. (1995) · Cell · doi:10.1016/0092-8674(95)90296-1 · Cited by 689 · see citing works

N‐WASP, a novel actin‐depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2‐dependent manner downstream of tyrosine kinases.

Miki, H., Miura, K., & Takenawa, T. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00917.x · Cited by 672 · see citing works

The structure of crystalline profilin–β-actin

Schutt, C. E., Myslik, J. C., Rozycki, M. D., Goonesekere, N. C. W., & Lindberg, U. (1993) · Nature · doi:10.1038/365810a0 · Cited by 664 · see citing works

Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain

Ferguson, K. M., Lemmon, M. A., Schlessinger, J., & Sigler, P. B. (1995) · Cell · doi:10.1016/0092-8674(95)90219-8 · Cited by 603 · see citing works

Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins

Li, C., Ullrich, B., Zhang, J. Z., Anderson, R. G. W., Brose, N., & Südhof, T. C. (1995) · Nature · doi:10.1038/375594a0 · Cited by 599 · see citing works

Phospholipid signaling

Divecha, N., & Irvine, R. F. (1995) · Cell · doi:10.1016/0092-8674(95)90409-3 · Cited by 568 · see citing works

Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain

Lemmon, M. A., Ferguson, K. M., O'Brien, R., Sigler, P. B., & Schlessinger, J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.23.10472 · Cited by 566 · see citing works

Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase.

Salim, K., Bottomley, M. J., Querfurth, E., Zvelebil, M., Gout, I. T., Scaife, R. M., Margolis, R. L., Gigg, R., Smith, C. I., Driscoll, P. C., et al. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb01014.x · Cited by 558 · see citing works

The GTPase dynamin binds to and is activated by a subset of SH3 domains

Gout, I. T., Dhand, R., Hiles, I. D., Fry, M., Panayotou, G., Das, P., Truong, O., Totty, N. F., Hsuan, J. J., Booker, G. W., et al. (1993) · Cell · doi:10.1016/s0092-8674(05)80081-9 · Cited by 557 · see citing works

Activation of phospholipase Cγ by PI 3‐kinase‐induced PH domain‐mediated membrane targeting

Falasca, M., Logan, S. K., Lehto, V. P., Baccante, G., Lemmon, M. A., & Schlessinger, J. (1998) · The EMBO Journal · doi:10.1093/emboj/17.2.414 · Cited by 557 · see citing works

Crystal structure of a mammalian phosphoinositide-specific phospholipase Cδ

Essen, L., Perišić, O., Cheung, R., Katan, M., & Williams, R. L. (1996) · Nature · doi:10.1038/380595a0 · Cited by 529 · see citing works

Phosphoinositides and Calcium as Regulators of Cellular Actin Assembly and Disassembly

Janmey, P. A. (1994) · Annual Review of Physiology · doi:10.1146/annurev.ph.56.030194.001125 · Cited by 522 · see citing works

An Alternative to SH2 Domains for Binding Tyrosine-Phosphorylated Proteins

Kavanaugh, W. M., & Williams, L. T. (1994) · Science · doi:10.1126/science.7527937 · Cited by 499 · see citing works

Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

Eck, M. J., Shoelson, S. E., & Harrison, S. C. (1993) · Nature · doi:10.1038/362087a0 · Cited by 499 · see citing works

Synaptotagmin I is a high affinity receptor for clathrin AP-2: implications for membrane recycling.

Zhang, J. Z., Davletov, B., Südhof, T., & Anderson, R. G. W. (1994) · Cell · doi:10.1016/s0092-8674(94)90442-1 · Cited by 495 · see citing works

The Dbl family of oncogenes

Cerione, R. A., & Zheng, Y. (1996) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(96)80068-8 · Cited by 492 · see citing works

Binding of G protein beta gamma-subunits to pleckstrin homology domains.

Touhara, K., Inglese, J., Pitcher, J. A., Shaw, G., & Lefkowitz, R. J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34048-6 · Cited by 483 · see citing works

Pleckstrin domain homology

Haslam, R. J., Koide, H., & Hemmings, B. A. (1993) · Nature · doi:10.1038/363309b0 · Cited by 480 · see citing works

A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.

Davletov, B. A., & Südhof, T. C. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74326-9 · Cited by 480 · see citing works

Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis

Dove, S. K., Cooke, F. T., Douglas, M. R., Sayers, L. G., Parker, P. J., & Michell, R. H. (1997) · Nature · doi:10.1038/36613 · Cited by 477 · see citing works

A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains

Chardin, P., Paris, S., Antonny, B., Robineau, S., Béraud-Dufour, S., Jackson, C. L., & Chabre, M. (1996) · Nature · doi:10.1038/384481a0 · Cited by 474 · see citing works

The Spectrin-Based Membrane Skeleton and Micron-Scale Organization of the Plasma Membrane

Bennett, V., & Gilligan, D. M. (1993) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.09.110193.000331 · Cited by 470 · see citing works

A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate

Rameh, L. E., Tolias, K. F., Duckworth, B. C., & Cantley, L. C. (1997) · Nature · doi:10.1038/36621 · Cited by 466 · see citing works

A Comparative Analysis of the Phosphoinositide Binding Specificity of Pleckstrin Homology Domains

Rameh, L. E., Arvidsson, A., Carraway, K. L., Couvillon, A. D., Rathbun, G. A., Crompton, A. M., VanRenterghem, B., Czech, M., Ravichandran, K. S., Burakoff, S. J., et al. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.35.22059 · Cited by 460 · see citing works

Coupling of Ras and Rac Guanosine Triphosphatases Through the Ras Exchanger Sos

Nimnual, A. S., Yatsula, B. A., & Bar‐Sagi, D. (1998) · Science · doi:10.1126/science.279.5350.560 · Cited by 451 · see citing works

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

Frech, M., Andjelković, M., Ingley, E., Reddy, K. K., Falck, J. R., & Hemmings, B. A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.13.8474 · Cited by 446 · see citing works

A putative modular domain present in diverse signaling proteins

Mayer, B. J., Ren, R., Clark, K., & Baltimore, D. (1993) · Cell · doi:10.1016/0092-8674(93)90244-k · Cited by 440 · see citing works

Phosphatidylinositol‐3,4,5‐trisphosphate (PtdIns‐3,4,5‐P3)/Tec kinase‐dependent calcium signaling pathway: a target for SHIP‐mediated inhibitory signals

Scharenberg, A. M., El-Hillal, O., Fruman, D. A., Beitz, L., Li, Z., Lin, S., Gout, I. T., Cantley, L. C., Rawlings, D. J., & Kinet, J.-P. (1998) · The EMBO Journal · doi:10.1093/emboj/17.7.1961 · Cited by 428 · see citing works

Signaling by Phosphoinositide-3,4,5-Trisphosphate Through Proteins Containing Pleckstrin and Sec7 Homology Domains

Klarlund, J. K., Guilherme, A., Holik, J. J., Virbasius, J. V., Chawla, A., & Czech, M. (1997) · Science · doi:10.1126/science.275.5308.1927 · Cited by 415 · see citing works

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B‐cell receptor activation

Fluckiger, A.-C., Li, Z., Kato, R. M., Wahl, M. I., Ochs, H. D., Longnecker, R., Kinet, J.-P., Witte, O. N., Scharenberg, A. M., & Rawlings, D. J. (1998) · The EMBO Journal · doi:10.1093/emboj/17.7.1973 · Cited by 403 · see citing works

Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin

Shirataki, H., Kaibuchi, K., Sakoda, T., Kishida, S., Yamaguchi, T., Wada, K., Miyazaki, M., & Takai, Y. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.4.2061-2068.1993 · Cited by 393 · see citing works

Phosphotyrosine-Dependent Interaction of SHC and Insulin Receptor Substrate 1 with the NPEY Motif of the Insulin Receptor via a Novel Non-SH2 Domain

Gustafson, T. A., He, W., Craparo, A., Schaub, C. D., & O’Neill, T. J. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.5.2500 · Cited by 374 · see citing works

Pleckstrin Homology Domain-mediated Membrane Association and Activation of the β-Adrenergic Receptor Kinase Requires Coordinate Interaction with Gβγ Subunits and Lipid

Pitcher, J. A., Touhara, K., Payne, E. S., & Lefkowitz, R. J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.20.11707 · Cited by 366 · see citing works

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

Zhou, M., Ravichandran, K. S., Olejniczak, E. T., Petros, A. M., Meadows, R. P., Sattler, M., Harlan, J. E., Wade, W. S., Burakoff, S. J., & Fesik, S. W. (1995) · Nature · doi:10.1038/378584a0 · Cited by 364 · see citing works

Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain.

Nalefski, E. A., Sultzman, L. A., Martin, D. M., Kriz, R., Towler, P., Knopf, J. L., & Clark, J. D. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32440-7 · Cited by 346 · see citing works

Structure of the binding site for inositol phosphates in a PH domain.

Hyvönen, M., Macias, M. J., Nilges, M., Oschkinat, H., Saraste, M., & Wilmanns, M. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb00149.x · Cited by 339 · see citing works

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

James, S. R., Downes, C. P., Gigg, R., Grove, S. J. A., Holmes, A. B., & Alessi, D. R. (1996) · Biochemical Journal · doi:10.1042/bj3150709 · Cited by 339 · see citing works

A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors.

Blaikie, P., Immanuel, D., Wu, J., Li, N., Yajnik, V., & Margolis, B. L. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)31593-x · Cited by 335 · see citing works

Activation of Phospholipase C-γ by Phosphatidylinositol 3,4,5-Trisphosphate

Bae, Y. S., Cantley, L. G., Chen, C.-S., Kim, S.-R., Kwon, K.-S., & Rhee, S. G. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.8.4465 · Cited by 330 · see citing works

Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor

Eck, M. J., Dhe‐Paganon, S., Trüb, T., Nolte, R. T., & Shoelson, S. E. (1996) · Cell · doi:10.1016/s0092-8674(00)81236-2 · Cited by 323 · see citing works

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

Rameh, L. E., Chen, C., & Cantley, L. C. (1995) · Cell · doi:10.1016/0092-8674(95)90195-7 · Cited by 317 · see citing works

The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C.

Yao, L., Kawakami, Y., & Kawakami, T. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.19.9175 · Cited by 316 · see citing works

PH domain: the first anniversary

Gibson, T. J., Hyvönen, M., Musacchio, A., Saraste, M., & Birney, E. (1994) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(94)90108-2 · Cited by 316 · see citing works

ERM proteins: head-to-tail regulation of actin-plasma membrane interaction

Tsukita, S., Yonemura, S., & Tsukita, S. (1997) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)10071-2 · Cited by 315 · see citing works

Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans

Jørgensen, E. M., Hartwieg, E. A., Schuske, K. R., Nonet, M. L., Jin, Y., & Horvitz, H. R. (1995) · Nature · doi:10.1038/378196a0 · Cited by 305 · see citing works

Bipartite Ca2+-Binding Motif in C2 Domains of Synaptotagmin and Protein Kinase C

Shao, X., Davletov, B., Sutton, R. B., Südhof, T., & Rizo, J. (1996) · Science · doi:10.1126/science.273.5272.248 · Cited by 303 · see citing works

The Crystal Structure of Plasma Gelsolin: Implications for Actin Severing, Capping, and Nucleation

Burtnick, L. D., Koepf, E. K., Grimes, J. M., Jones, E. Y., Stuart, D. I., McLaughlin, P. J., & Robinson, R. C. (1997) · Cell · doi:10.1016/s0092-8674(00)80527-9 · Cited by 296 · see citing works

Identification of a specific lns(l,3,4,5)P4-binding protein as a member of the GAP1 family

Cullen, P. J., Hsuan, J. J., Truong, O., Letcher, A. J., Jackson, T., Dawson, A. P., & Irvine, R. F. (1995) · Nature · doi:10.1038/376527a0 · Cited by 295 · see citing works

Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis

Bommert, K., Charlton, M. P., DeBello, W. M., Chin, G. J., Betz, H., & Augustine, G. J. (1993) · Nature · doi:10.1038/363163a0 · Cited by 278 · see citing works

Crystal structure at 2.2 Å resolution of the pleckstrin homology domain from human dynamin

Ferguson, K. M. (1994) · Cell · doi:10.1016/0092-8674(94)90190-2 · Cited by 270 · see citing works

Identification of the Binding Site for Acidic Phospholipids on the PH Domain of Dynamin: Implications for Stimulation of GTPase Activity

Zheng, J., Cahill, S. M., Lemmon, M. A., Fushman, D., Schlessinger, J., & Cowburn, D. (1996) · Journal of Molecular Biology · doi:10.1006/jmbi.1996.0002 · Cited by 253 · see citing works

Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase

Kanamarlapudi, V., Oatey, P. B., Tavaré, J. M., & Cullen, P. J. (1998) · Current Biology · doi:10.1016/s0960-9822(98)70181-2 · Cited by 251 · see citing works

The PTB domain: a new protein module implicated in signal transduction

van der Geer, P., & Pawson, T. J. (1995) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)89043-x · Cited by 246 · see citing works

Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains.

Hope, H. R., & PIKE, L. J. (1996) · Molecular Biology of the Cell · doi:10.1091/mbc.7.6.843 · Cited by 241 · see citing works

Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X‐linked agammaglobulinaemia

Hyvönen, M., & Saraste, M. (1997) · The EMBO Journal · doi:10.1093/emboj/16.12.3396 · Cited by 241 · see citing works

Domain structure and intramolecular regulation of dynamin GTPase

Muhlberg, A. B., Warnock, D. E., & Schmid, S. L. (1997) · The EMBO Journal · doi:10.1093/emboj/16.22.6676 · Cited by 240 · see citing works

Structure of the pleckstrin homology domain from β-spectrin

Macías, M. J., Musacchio, A., Ponstingl, H., Nilges, M., Saraste, M., & Oschkinat, H. (1994) · Nature · doi:10.1038/369675a0 · Cited by 239 · see citing works

Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase.

Tsukada, S., Simon, M. I., Witte, O. N., & Katz, A. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.23.11256 · Cited by 238 · see citing works

Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II.

Fukuda, M., Aruga, J., Niinobe, M., Aimoto, S., & Mikoshiba, K. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)62031-4 · Cited by 237 · see citing works

Regulated Membrane Localization of Tiam1, Mediated by the NH2-terminal Pleckstrin Homology Domain, Is Required for Rac-dependent Membrane Ruffling and C-Jun NH2-terminal Kinase Activation

Michiels, F., Stam, J. C., Hordijk, P. L., van der Kammen, R. A., Stalle, L. R.-V., Feltkamp, C. A., & Collard, J. G. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.137.2.387 · Cited by 232 · see citing works

Identification of a polyphosphoinositide-binding sequence in an actin monomer-binding domain of gelsolin.

Yu, F. X., Sun, H. Q., Janmey, P. A., & Yin, H. L. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42086-8 · Cited by 224 · see citing works

Solution structure of a pleckstrin-homology domain

Yoon, H. S., Hajduk, P. J., Petros, A. M., Olejniczak, E. T., Meadows, R. P., & Fesik, S. W. (1994) · Nature · doi:10.1038/369672a0 · Cited by 212 · see citing works

Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase

Lee, C., Kominos, D., Jacques, S. L., Margolis, B. L., Schlessinger, J., Shoelson, S. E., & Kuriyan, J. (1994) · Structure · doi:10.1016/s0969-2126(00)00044-7 · Cited by 205 · see citing works

Mutation of the Pleckstrin Homology Domain of Bruton's Tyrosine Kinase in Immunodeficiency Impaired Inositol 1,3,4,5-Tetrakisphosphate Binding Capacity

Fukuda, M., Kojima, T., Kabayama, H., & Mikoshiba, K. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.48.30303 · Cited by 201 · see citing works

Lipid-Regulated Kinases: Some Common Themes at Last

Downward, J. (1998) · Science · doi:10.1126/science.279.5351.673 · Cited by 198 · see citing works

Molecular Cloning and Characterization of a New Member of the RAC Protein Kinase Family: Association of the Pleckstrin Homology Domain of 3 Types of RAC Protein Kinase with Protein Kinase C Subspecies and βγ Subunits of G Proteins

Konishi, H., Kuroda, S., Tanaka, M., Matsuzaki, H., Ono, Y., Kameyama, K., Haga, T., & Kikkawa, U. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.2654 · Cited by 192 · see citing works

A Novel Function for the Second C2 Domain of Synaptotagmin

Chapman, E. R., An, S. J., Edwardson, J., & Jahn, R. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.10.5844 · Cited by 191 · see citing works

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