The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Microfluidic Large-Scale Integration: The Evolution of Design Rules for Biological Automation
Abstract
Microfluidic large-scale integration (mLSI) refers to the development of microfluidic chips with thousands of integrated micromechanical valves and control components. This technology is utilized in many areas of biology and chemistry and is a candidate to replace today's conventional automation paradigm, which consists of fluid-handling robots. We review the basic development of mLSI and then discuss design principles of mLSI to assess the capabilities and limitations of the current state of the art and to facilitate the application of mLSI to areas of biology. Many design and practical issues, including economies of scale, parallelization strategies, multiplexing, and multistep biochemical processing, are discussed. Several microfluidic components used as building blocks to create effective, complex, and highly integrated microfluidic networks are also highlighted.
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Citations
Cites
The origins and the future of microfluidics
Whitesides, G. M. (2006) · Nature · doi:10.1038/nature05058 · Cited by 9,687
Solvent Compatibility of Poly(dimethylsiloxane)-Based Microfluidic Devices
Lee, J. N., Park, C., & Whitesides, G. M. (2003) · Analytical Chemistry · doi:10.1021/ac0346712 · Cited by 2,643
Cited by
Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices
Halldorsson, S., Lucumi, E., Gómez-Sjöberg, R., & Fleming, R. M. T. (2015) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2014.07.029 · Cited by 1,027
Making it stick: convection, reaction and diffusion in surface-based biosensors
Squires, T. M., Messinger, R. J., & Manalis, S. R. (2008) · Nature Biotechnology · doi:10.1038/nbt1388 · Cited by 986
Prebiotic Systems Chemistry: New Perspectives for the Origins of Life
Ruiz-Mirazo, K., Briones, C., & de la Escosura, A. (2014) · Chemical Reviews · doi:10.1021/cr2004844 · Cited by 930
Au, A. K., Huynh, W., Horowitz, L. F., & Folch, A. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201504382 · Cited by 788
Design of pressure-driven microfluidic networks using electric circuit analogy
Oh, K. W., Lee, K., Ahn, B., & Furlani, E. P. (2012) · Lab Chip · doi:10.1039/c2lc20799k · Cited by 685
Metadata
- Authors
- Melin, J., & Quake, S. R.
- Venue
- Annual Review of Biophysics and Biomolecular Structure
- Publisher
- Annual Reviews
- Published
- 2007-06-01
- Volume
- 36
- Issue
- 1
- Pages
- 213-231
- ISSN
- 1056-8700 (ISSN-L)
- 1545-4266
- OpenAlex
- W2110460556
- Cited by
- 738
- References
- 2
- FWCI
- 28.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- Melin, J., & Quake, S. R. (2007). Microfluidic Large-Scale Integration: The Evolution of Design Rules for Biological Automation. Annual Review of Biophysics and Biomolecular Structure. https://doi.org/10.1146/annurev.biophys.36.040306.132646
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
