The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Metal Binding Affinity and Selectivity in Metalloproteins: Insights from Computational Studies
Abstract
This review highlights insights gained from computational studies on protein-metal recognition. We systematically dissect the various factors governing metal binding affinity and selectivity in proteins starting from (a) the intrinsic properties of the metal and neighboring metal cations (if present), to (b) the primary coordination sphere, (c) the second coordination shell, (d) the protein matrix, (e) the bulk solvent, and (f) competing non-protein ligands from the surrounding biological environment. The results herein reveal the fundamental principles and the molecular bases underlying protein-metal recognition, which serve as a guide to engineer novel metalloproteins with programmed properties.
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Cites
Structure and mechanism of carbonic anhydrase
Lindskog, S. (1997) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(96)00198-2 · Cited by 1,022
Cited by
Metalloproteins and metal sensing
Waldron, K. J., Rutherford, J. C., Ford, D., & Robinson, N. J. (2009) · Nature · doi:10.1038/nature08300 · Cited by 1,269
The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles
Chang, Y.-N., Zhang, M., Xia, L., Zhang, J., & Xing, G. (2012) · Materials · doi:10.3390/ma5122850 · Cited by 772
Dudev, T., & Lim, C. (2014) · Chemical Reviews · doi:10.1021/cr4004665 · Cited by 451
Self-citationJohnson, M. D. L., Kehl-Fie, T. E., Klein, R., Kelly, J., Burnham, C., Mann, B., & Rosch, J. W. (2015) · Infection and Immunity · doi:10.1128/iai.03015-14 · Cited by 84
Karki, I., Christen, M. T., Spiriti, J., Slack, R. L., Oda, M., Kanaori, K., Zuckerman, D. M., & Ishima, R. (2016) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.6b08323 · Cited by 5
Metadata
- Authors
- Dudev, T., & Lim, C.
- Venue
- Annual Review of Biophysics
- Publisher
- Annual Reviews
- Published
- 2008-06-01
- Volume
- 37
- Issue
- 1
- Pages
- 97-116
- ISSN
- 1936-122X (ISSN-L)
- 1936-1238
- OpenAlex
- W2101337181
- Cited by
- 232
- References
- 1
- FWCI
- 0.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dudev, T., & Lim, C. (2008). Metal Binding Affinity and Selectivity in Metalloproteins: Insights from Computational Studies. Annual Review of Biophysics. https://doi.org/10.1146/annurev.biophys.37.032807.125811
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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