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Cited by 278

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

ASSEMBLY OF VARIANT HISTONES INTO CHROMATIN

Henikoff, Steven, Ahmad, Kami·2005·Annual Review of Cell and Developmental Biology

Abstract

Chromatin can be differentiated by the deposition of variant histones at centromeres, active genes, and silent loci. Variant histones are assembled into nucleosomes in a replication-independent manner, in contrast to assembly of bulk chromatin that is coupled to replication. Recent in vitro studies have provided the first glimpses of protein machines dedicated to building and replacing alternative nucleosomes. They deposit variant H2A and H3 histones and are targeted to particular functional sites in the genome. Differences between variant and canonical histones can have profound consequences, either for delivery of the histones to sites of assembly or for their function after incorporation into chromatin. Recent studies have also revealed connections between assembly of variant nucleosomes, chromatin remodeling, and histone post-translational modification. Taken together, these findings indicate that chromosome architecture can be highly dynamic at the most fundamental level, with epigenetic consequences.

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Metadata

Authors
Henikoff, S., & Ahmad, K.
Venue
Annual Review of Cell and Developmental Biology
Published
2005-11-01
Volume
21
Issue
1
Pages
133-153
ISSN
  • 1081-0706 (ISSN-L)
  • 1530-8995
OpenAlex
W2150402790
Cited by
278
References
4
FWCI
1.73
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: ASSEMBLY OF VARIANT HISTONES INTO CHROMATIN. https://app.cochat.ai/papers/10.1146/annurev.cellbio.21.012704.133518
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Henikoff, S., & Ahmad, K. (2005). ASSEMBLY OF VARIANT HISTONES INTO CHROMATIN. Annual Review of Cell and Developmental Biology. https://doi.org/10.1146/annurev.cellbio.21.012704.133518

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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