The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.
THE GREAT ESCAPE: When Cancer Cells Hijack the Genes for Chemotaxis and Motility
Abstract
The combined use of the new technologies of multiphoton-based intravital imaging, the chemotaxis-mediated collection of invasive cells, and high sensitivity expression profiling has allowed the correlation of the behavior of invasive tumor cells in vivo with their gene expression patterns. New insights have resulted including a gene expression signature for invasive cells and the tumor microenvironment invasion model. This model proposes that tumor invasion and metastasis can be studied as a problem resembling normal morphogenesis. We discuss how these new insights may lead to a better understanding of the molecular basis of the invasive behavior of tumor cells in vivo, which may result in new strategies for the diagnosis and treatment of metastasis.
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Cites
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Provenzano, P. P., Inman, D. R., Eliceiri, K. W., Knittel, J. G., Yan, L., Rueden, C. T., White, J. G., & Keely, P. J. (2008) · BMC Medicine · doi:10.1186/1741-7015-6-11 · Cited by 1,361
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Metadata
- Authors
- Condeelis, J., Singer, R. H., & Segall, J. E.
- Venue
- Annual Review of Cell and Developmental Biology
- Publisher
- Annual Reviews
- Published
- 2005-11-01
- Volume
- 21
- Issue
- 1
- Pages
- 695-718
- ISSN
- 1081-0706 (ISSN-L)
- 1530-8995
- OpenAlex
- W2164282019
- Cited by
- 391
- References
- 105
- FWCI
- 1.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: THE GREAT ESCAPE: When Cancer Cells Hijack the Genes for Chemotaxis and Motility. https://app.cochat.ai/papers/10.1146/annurev.cellbio.21.122303.120306
- The paper
- Condeelis, J., Singer, R. H., & Segall, J. E. (2005). THE GREAT ESCAPE: When Cancer Cells Hijack the Genes for Chemotaxis and Motility. Annual Review of Cell and Developmental Biology. https://doi.org/10.1146/annurev.cellbio.21.122303.120306
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
