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CONSERVATION GENETICS
Abstract
Inbreeding depression, accumulation and loss of deleterious mutations, loss of genetic variation in small populations, genetic adaptation to captivity and its effect on reintroduction success, and outbreeding depression are reviewed. The impact of genetic factors in endangerment and extinction has been underestimated in some recent publications. Inbreeding depression in wildlife and in the field has been clearly established, while its impact has been greatly underestimated. The size of populations where genetic factors become important is higher than previously recognized, as Ne/N ratios average 0.11. Purging effects have been overestimated as a mechanism for eliminating deleterious alleles in small populations. The impact of loss of genetic variation in increasing the susceptibility of populations to environmental stochasticity and catastrophes has generally been ignored. Consequently, extinctions are often attributed to "nongenetic" factors when these may have interacted with genetic factors to cause extinction.
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Cited by
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Meagher, S., Penn, D. J., & Potts, W. K. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.7.3324 · Cited by 322
Human influences on evolution, and the ecological and societal consequences
Hendry, A. P., Gotanda, K. M., & Svensson, E. I. (2017) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2016.0028 · Cited by 298
Conservation genetics of population bottlenecks: the role of chance, selection, and history
Bouzat, J. L. (2010) · Conservation Genetics · doi:10.1007/s10592-010-0049-0 · Cited by 289
The Effects of a Bottleneck on Inbreeding Depression and the Genetic Load
Kirkpatrick, M., & Jarne, P. (2000) · The American Naturalist · doi:10.1086/303312 · Cited by 271
Genetic diversity, inbreeding and breeding practices in dogs: Results from pedigree analyses
Leroy, G. (2011) · The Veterinary Journal · doi:10.1016/j.tvjl.2011.06.016 · Cited by 143
Metadata
- Authors
- Frankham, R.
- Venue
- Annual Review of Genetics
- Publisher
- Annual Reviews
- Published
- 1995-12
- Volume
- 29
- Issue
- 1
- Pages
- 305-327
- ISSN
- 0066-4197 (ISSN-L)
- 1545-2948
- OpenAlex
- W4246640010
- Cited by
- 1,050
- References
- 0
- FWCI
- 6.49
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
