The DOI matches its Crossref record; 144 of the 144 references it cites were found in a registry or an index.
VIVE LA DIFFÉRENCE: Males vs Females in Flies vs Worms
Abstract
▪ Abstract For 600 million years, the two best-understood metazoan species, the nematode Caenorhabditis elegans and the fruit fly Drosophila melanogaster, have developed independent strategies for solving a biological problem faced by essentially all metazoans: how to generate two sexes in the proper proportions. The genetic program for sexual dimorphism has been a major focus of research in these two organisms almost from the moment they were chosen for study, and it may now be the best-understood general aspect of their development. In this review, we compare and contrast the strategies used for sex determination (including dosage compensation) between “the fly” and “the worm” and the way this understanding has come about. Although no overlap has been found among the molecules used by flies and worms to achieve sex determination, striking similarities have been found in the genetic strategies used by these two species to differentiate their sexes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
THE GENETICS OF CAENORHABDITIS ELEGANS
Brenner, S. (1974) · Genetics · doi:10.1093/genetics/77.1.71 · Cited by 15,081
The embryonic cell lineage of the nematode Caenorhabditis elegans
Sulston, J. E., Schierenberg, E., White, J. G., & Thomson, J. N. (1983) · Developmental Biology · doi:10.1016/0012-1606(83)90201-4 · Cited by 4,199
Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
Sulston, J. E., & Horvitz, H. R. (1977) · Developmental Biology · doi:10.1016/0012-1606(77)90158-0 · Cited by 3,475
DEVELOPMENT IN DROSOPHILA MELANOGASTER
Li, J.-C. (1927) · Genetics · doi:10.1093/genetics/12.2.198 · Cited by 2,852
Murre, C., McCaw, P. S., & Baltimore, D. (1989) · Cell · doi:10.1016/0092-8674(89)90682-x · Cited by 2,635
Evolution of sex determining mechanisms
Bull, J. J. (1983) · Medical Entomology and Zoology · Cited by 1,527
The postembryonic cell lineages of the hermaphrodite and male gonads in Caenorhabditis elegans
Kimble, J., & Hirsh, D. (1979) · Developmental Biology · doi:10.1016/0012-1606(79)90035-6 · Cited by 880
Burtis, K. C., & Baker, B. S. (1989) · Cell · doi:10.1016/0092-8674(89)90633-8 · Cited by 708
PAROUSH, Z. (1994) · Cell · doi:10.1016/0092-8674(94)90070-1 · Cited by 563
Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans
Sulston, J. E., & White, J. G. (1980) · Developmental Biology · doi:10.1016/0012-1606(80)90353-x · Cited by 559
Cited by
The Master Sex-Determination Locus in Threespine Sticklebacks Is on a Nascent Y Chromosome
Peichel, C. L., Ross, J. A., Matson, C. K., Dickson, M., Grimwood, J., Schmutz, J., Myers, R. M., Mori, S., Schluter, D., & Kingsley, D. M. (2004) · Current Biology · doi:10.1016/j.cub.2004.08.030 · Cited by 420
Sex chromosomes and brain gender
Arnold, A. P. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1494 · Cited by 368
Sex and the Single Cell. II. There Is a Time and Place for Sex
Robinett, C. C., Vaughan, A. G., Knapp, J.-M., & Baker, B. S. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000365 · Cited by 242
The JAK/STAT Pathway in Model Organisms
Hou, S. X., Zheng, Z., Chen, X., & Perrimon, N. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00376-3 · Cited by 251
The TAGteam DNA motif controls the timing of Drosophila pre-blastoderm transcription
Bosch, J. R. T., Benavides, J. A., & Cline, T. W. (2006) · Development · doi:10.1242/dev.02373 · Cited by 161
Self-citation
Metadata
- Authors
- Cline, T. W., & Meyer, B. J.
- Venue
- Annual Review of Genetics
- Publisher
- Annual Reviews
- Published
- 1996-12
- Volume
- 30
- Issue
- 1
- Pages
- 637-702
- ISSN
- 0066-4197 (ISSN-L)
- 1545-2948
- OpenAlex
- W2169580261
- Cited by
- 600
- References
- 144
- FWCI
- 3.88
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: VIVE LA DIFFÉRENCE: Males vs Females in Flies vs Worms. https://app.cochat.ai/papers/10.1146/annurev.genet.30.1.637
- The paper
- Cline, T. W., & Meyer, B. J. (1996). VIVE LA DIFFÉRENCE: Males vs Females in Flies vs Worms. Annual Review of Genetics. https://doi.org/10.1146/annurev.genet.30.1.637
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
