The JAK/STAT Pathway in Model Organisms

The development of Drosophila melanogaster

Ingham, P. W. (1994) · Trends in Genetics · doi:10.1016/0168-9525(90)90017-z · Cited by 3,158 · see citing works

DEVELOPMENT IN DROSOPHILA MELANOGASTER

Li, J.-C. (1927) · Genetics · doi:10.1093/genetics/12.2.198 · Cited by 2,887 · see citing works

Stat3 as an Oncogene

Bromberg, J. F., Wrzeszczynska, M. H., Devgan, G., Zhao, Y., Pestell, R. G., Albanese, C., & Darnell, J. E. (1999) · Cell · doi:10.1016/s0092-8674(00)81959-5 · Cited by 2,790 · see citing works

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway

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Targeted disruption of the mouse <i>Stat3</i> gene leads to early embryonic lethality

Takeda, K., Noguchi, K., Shi, W., Tanaka, T., Matsumoto, M., Yoshida, N., Kishimoto, T., & Akira, S. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.8.3801 · Cited by 1,323 · see citing works

Cytokine Signaling in 2002

O’Shea, J. J., Gadina, M., & Schreiber, R. D. (2002) · Cell · doi:10.1016/s0092-8674(02)00701-8 · Cited by 1,119 · see citing works

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

Heisenberg, C.-P., Tada, M., Rauch, G.-J., Saúde, L., Concha, M. L., Geisler, R., Stemple, D. L., Smith, J. C., & Wilson, S. W. (2000) · Nature · doi:10.1038/35011068 · Cited by 1,013 · see citing works

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

Matsuda, T., Nakamura, T., Nakao, K., Arai, T., Katsuki, M., Heike, T., & Yokota, T. (1999) · The EMBO Journal · doi:10.1093/emboj/18.15.4261 · Cited by 896 · see citing works

Developmental genetics of oogenesis

Spradling, A. C. (1993) · Medical Entomology and Zoology · Cited by 850 · see citing works

Stat proteins and oncogenesis

Bromberg, J. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15617 · Cited by 846 · see citing works

A TEL-JAK2 Fusion Protein with Constitutive Kinase Activity in Human Leukemia

Penard‐Lacronique, V., Boureux, A., Della-Valle, V., Poirel, H. A., Quang, C. T., Mauchauffé, M., Berthou, C., Lessard, M., Berger, R., Ghysdael, J., et al. (1997) · Science · doi:10.1126/science.278.5341.1309 · Cited by 790 · see citing works

Stem Cell Self-Renewal Specified by JAK-STAT Activation in Response to a Support Cell Cue

Kiger, A. A., Jones, D. L., Schulz, C., Rogers, M. B., & Fuller, M. T. (2001) · Science · doi:10.1126/science.1066707 · Cited by 698 · see citing works

Embryonic mesodermal defects in α5 integrin-deficient mice

Yang, J. T., Rayburn, H., & Hynes, R. O. (1993) · Development · doi:10.1242/dev.119.4.1093 · Cited by 691 · see citing works

The evolution and genetics of innate immunity

Kimbrell, D., & Beutler, B. (2001) · Nature reviews genetics · doi:10.1038/35066006 · Cited by 679 · see citing works

Control of Stem Cell Self-Renewal in Drosophila Spermatogenesis by JAK-STAT Signaling

Tulina, N. M., & Matunis, E. L. (2001) · Science · doi:10.1126/science.1066700 · Cited by 653 · see citing works

branchless Encodes a Drosophila FGF Homolog That Controls Tracheal Cell Migration and the Pattern of Branching

Sutherland, D., Samakovlis, C., & Krasnow, M. A. (1996) · Cell · doi:10.1016/s0092-8674(00)81803-6 · Cited by 652 · see citing works

Postembryonic Hematopoiesis in Drosophila

Lanot, R., Zachary, D., Holder, F., & Meister, M. F. (2001) · Developmental Biology · doi:10.1006/dbio.2000.0123 · Cited by 633 · see citing works

Convergent Extension

Wallingford, J. B., Fraser, S. E., & Harland, R. M. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00197-1 · Cited by 613 · see citing works

The Jak-STAT pathway

Imada, K., & Leonard, W. J. (2000) · Molecular Immunology · doi:10.1016/s0161-5890(00)00018-3 · Cited by 610 · see citing works

VIVE LA DIFFÉRENCE: Males vs Females in Flies vs Worms

Cline, T. W., & Meyer, B. J. (1996) · Annual Review of Genetics · doi:10.1146/annurev.genet.30.1.637 · Cited by 610 · see citing works

Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells

Moriggl, R., Topham, D. J., Teglund, S., Sexl, V., McKay, C., Wang, D., Hoffmeyer, A., van Deursen, J., Sangster, M. Y., Bunting, K. D., et al. (1999) · Immunity · doi:10.1016/s1074-7613(00)80025-4 · Cited by 546 · see citing works

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

Sano, S., Itami, S., Takeda, K., Tarutani, M., Yamaguchi, Y., Miura, H., Yoshikawa, K., Akira, S., & Takeda, J. (1999) · The EMBO Journal · doi:10.1093/emboj/18.17.4657 · Cited by 519 · see citing works

Sequential Activation of Signaling Pathways during Innate Immune Responses in Drosophila

Boutros, M., Agaisse, H., & Perrimon, N. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00325-8 · Cited by 516 · see citing works

Genetic Control of Branching Morphogenesis

Metzger, R. J., & Krasnow, M. A. (1999) · Science · doi:10.1126/science.284.5420.1635 · Cited by 502 · see citing works

Specification of Drosophila Hematopoietic Lineage by Conserved Transcription Factors

Lebestky, T., Chang, T., Hartenstein, V., & Banerjee, U. K. (2000) · Science · doi:10.1126/science.288.5463.146 · Cited by 494 · see citing works

Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.

Harrison, D. A., Binari, R. C., Nahreini, T. S., Gilman, M. Z., & Perrimon, N. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07285.x · Cited by 469 · see citing works

Planar Signaling and Morphogenesis in Drosophila

Adler, P. N. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00176-4 · Cited by 443 · see citing works

Embryonic origin of hemocytes and their relationship to cell death in Drosophila

Tepaß, U., Fessler, L. I., Aziz, A., & Hartenstein, V. (1994) · Development · doi:10.1242/dev.120.7.1829 · Cited by 420 · see citing works

Somatic support cells restrict germline stem cell self-renewal and promote differentiation

Kiger, A. A., White‐Cooper, H., & Fuller, M. T. (2000) · Nature · doi:10.1038/35037606 · Cited by 407 · see citing works

The Rho GTPase and a Putative RhoGEF Mediate a Signaling Pathway for the Cell Shape Changes in Drosophila Gastrulation

Barrett, K., Leptin, M., & Settleman, J. E. (1997) · Cell · doi:10.1016/s0092-8674(00)80482-1 · Cited by 400 · see citing works

Identification of a Stat Gene That Functions in Drosophila Development

Yan, R., Small, S., Desplan, C., Dearolf, C. R., & Darnell, J. E., Jr. (1996) · Cell · doi:10.1016/s0092-8674(00)81287-8 · Cited by 399 · see citing works

Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathwayPreprint

Harrison, D. A., Mccoon, P. E., Binari, R. C., Gilman, M. Z., & Perrimon, N. (1998) · Genes & Development · doi:10.1101/gad.12.20.3252 · Cited by 386 · see citing works

Modulation of STAT signaling by STAT-interacting proteins

Shuai, K. (2000) · Oncogene · doi:10.1038/sj.onc.1203522 · Cited by 379 · see citing works

marelle Acts Downstream of the Drosophila HOP/JAK Kinase and Encodes a Protein Similar to the Mammalian STATs

Hou, X. S., Melnick, M. B., & Perrimon, N. (1996) · Cell · doi:10.1016/s0092-8674(00)81286-6 · Cited by 374 · see citing works

Regulation of Frizzled by Fat-like Cadherins during Planar Polarity Signaling in the Drosophila Compound Eye

Yang, C.-H., Axelrod, J. D., & Simon, M. A. (2002) · Cell · doi:10.1016/s0092-8674(02)00658-x · Cited by 373 · see citing works

Capacitative calcium entry channels

Putney, J. W., & McKay, R. R. (1999) · BioEssays · doi:10.1002/(sici)1521-1878(199901)21:1 · Cited by 373 · see citing works

Identification of the first invertebrate interleukin JAK/STAT receptor, the Drosophila gene domeless

Brown, S., Hu, N., & Hombría, J. C. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00524-3 · Cited by 351 · see citing works

An amino acid substitution in the Drosophila hopTum‐l Jak kinase causes leukemia‐like hematopoietic defects.

Luo, H. R., Hanratty, W. P., & Dearolf, C. R. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07127.x · Cited by 322 · see citing works

Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila.Preprint

Binari, R. C., & Perrimon, N. (1994) · Genes & Development · doi:10.1101/gad.8.3.300 · Cited by 319 · see citing works

DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in DrosophilaPreprint

Häcker, U., & Perrimon, N. (1998) · Genes & Development · doi:10.1101/gad.12.2.274 · Cited by 305 · see citing works

Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants of Drosophila

Lagueux, M., Perrodou, E., Levashina, E. A., Capovilla, M., & Hoffmann, J. A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.21.11427 · Cited by 303 · see citing works

Stat5 Is Essential for the Myelo- and Lymphoproliferative Disease Induced by TEL/JAK2

Schwaller, J., Parganas, E., Wang, D., Cain, D., Aster, J. C., Williams, I. R., Lee, C., Gerthner, R., Kitamura, T., Frantsve‐Hawley, J., et al. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00067-8 · Cited by 303 · see citing works

Paracrine Signaling through the JAK/STAT Pathway Activates Invasive Behavior of Ovarian Epithelial Cells in Drosophila

Silver, D. L., & Montell, D. J. (2001) · Cell · doi:10.1016/s0092-8674(01)00607-9 · Cited by 300 · see citing works

Somatic control over the germline stem cell lineage during Drosophila spermatogenesis

Tran, J., Brenner, T. J., & DiNardo, S. (2000) · Nature · doi:10.1038/35037613 · Cited by 266 · see citing works

Mutation in the Jak Kinase JH2 Domain Hyperactivates Drosophila and Mammalian Jak-Stat Pathways

Luo, H., Rose, P., Barber, D. L., Hanratty, W. P., Lee, S., Roberts, T. M., D’Andrea, A. D., & Dearolf, C. R. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.3.1562 · Cited by 242 · see citing works

Regulation of Two Pair-Rule Stripes by a Single Enhancer in theDrosophilaEmbryo

Small, S., Blair, A., & Levine, M. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0117 · Cited by 240 · see citing works

SH2 Signaling in a Lower Eukaryote: A STAT Protein That Regulates Stalk Cell Differentiation in Dictyostelium

Kawata, T., Shevchenko, A., Fukuzawa, M., Jermyn, K. A., Totty, N. F., Zhukovskaya, N. V., Sterling, A., Mann, M., & Williams, J. G. (1997) · Cell · doi:10.1016/s0092-8674(00)80276-7 · Cited by 231 · see citing works

IFNs and STATs in innate immunity to microorganisms

Decker, T., Stockinger, S., Karaghiosoff, M., Müller, M. M., & Kovarik, P. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15770 · Cited by 230 · see citing works

Regulation of STAT3 by Direct Binding to the Rac1 GTPase

Simon, A. R., Vikis, H. G., Stewart, S., Fanburg, B. L., Cochran, B., & Guan, K. (2000) · Science · doi:10.1126/science.290.5489.144 · Cited by 224 · see citing works

Anopheles gambiae Ag‐STAT, a new insect member of the STAT family, is activated in response to bacterial infection

Barillas-Mury, C. V., Han, Y.-S., Seeley, D. C., & Kafatos, F. C. (1999) · The EMBO Journal · doi:10.1093/emboj/18.4.959 · Cited by 218 · see citing works

Series Introduction: JAK-STAT signaling in human disease

Schindler, C. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15644 · Cited by 217 · see citing works

Series Introduction: JAK-STAT signaling in human disease

Schindler, C. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215644 · Cited by 200 · see citing works

IFNs and STATs in innate immunity to microorganisms

Decker, T., Stockinger, S., Karaghiosoff, M., Müller, M. M., & Kovarik, P. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215770 · Cited by 191 · see citing works

The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein familyPreprint

Hari, K. L., Cook, K. R., & Karpen, G. H. (2001) · Genes & Development · doi:10.1101/gad.877901 · Cited by 187 · see citing works

Antiapoptotic activity ofStat5required during terminal stages of myeloid differentiationPreprint

Kieslinger, M., Woldman, I., Moriggl, R., Hofmann, J. F.-X., Marine, J., Ihle, J. N., Beug, H., & Decker, T. (2000) · Genes & Development · doi:10.1101/gad.14.2.232 · Cited by 185 · see citing works

Origins of the prestalk-prespore pattern in Dictyostelium development

Williams, J. G., Duffy, K. T., Lane, D. P., McRobbie, S. J., Harwood, A. J., Traynor, D., Kay, R. R., & Jermyn, K. A. (1989) · Cell · doi:10.1016/0092-8674(89)90771-x · Cited by 184 · see citing works

Stat3 Controls Cell Movements during Zebrafish Gastrulation

Yamashita, S., Miyagi, C., Carmany-Rampey, A., Shimizu, T., Fujii, R., Schier, A. F., & Hirano, T. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00126-0 · Cited by 178 · see citing works

The Fertile Field of Drosophila JAK/STAT Signalling

Hombría, J. C., & Brown, S. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01057-6 · Cited by 172 · see citing works

The roles of the Drosophila JAK/STAT pathway

Zeidler, M. P., Bach, E. A., & Perrimon, N. (2000) · Oncogene · doi:10.1038/sj.onc.1203482 · Cited by 172 · see citing works

mom identifies a receptor for the Drosophila JAK/STAT signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor familyPreprint

Chen, H., Chen, X., Oh, S., Marinissen, M. J., Gutkind, J. S., & Hou, X. S. (2002) · Genes & Development · doi:10.1101/gad.955202 · Cited by 171 · see citing works

Convergence and extension in vertebrate gastrulae: cell movements according to or in search of identity?

Myers, D. C., Sepich, D. S., & Solnica‐Krezel, L. (2002) · Trends in Genetics · doi:10.1016/s0168-9525(02)02725-7 · Cited by 169 · see citing works

The N-termini of FAK and JAKs contain divergent band 4.1 domains

Girault, J., Labesse, G., Mornon, J., & Callebaut, I. (1999) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(98)01331-0 · Cited by 168 · see citing works

Polarity determination in the Drosophila eye: a novel role for Unpaired and JAK/STAT signalingPreprint

Zeidler, M. P., Perrimon, N., & Strutt, D. I. (1999) · Genes & Development · doi:10.1101/gad.13.10.1342 · Cited by 167 · see citing works

JAK signaling is somatically required for follicle cell differentiation inDrosophila

McGregor, J. R., Xi, R., & Harrison, D. A. (2002) · Development · doi:10.1242/dev.129.3.705 · Cited by 160 · see citing works

SOCS36E, a novel Drosophila SOCS protein, suppresses JAK/STAT and EGF-R signalling in the imaginal wing disc

Callus, B. A., & Mathey-Prévôt, B. (2002) · Oncogene · doi:10.1038/sj.onc.1205618 · Cited by 157 · see citing works

It takes guts: the Drosophila hindgut as a model system for organogenesis.

Lengyel, J., & Iwaki, D. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0577 · Cited by 157 · see citing works

The JAK/STAT pathway is required for border cell migration during Drosophila oogenesis

Beccari, S., Teixeira, L., & Rørth, P. (2002) · Mechanisms of Development · doi:10.1016/s0925-4773(01)00615-3 · Cited by 150 · see citing works

Male Germ Cell Specification and Differentiation

Zhao, G.-Q., & Garbers, D. L. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00173-9 · Cited by 149 · see citing works

Vive la différence!

Berkley, K. J. (1992) · Trends in Neurosciences · doi:10.1016/0166-2236(92)90048-d · Cited by 142 · see citing works

four-jointed is required for intermediate growth in the proximal-distal axis in Drosophila

Villano, J. L., & Katz, F. N. (1995) · Development · doi:10.1242/dev.121.9.2767 · Cited by 140 · see citing works

The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification

Zeidler, M. P., Perrimon, N., & Strutt, D. I. (1999) · Current Biology · doi:10.1016/s0960-9822(00)80081-0 · Cited by 139 · see citing works

Multiple Roles for four-jointed in Planar Polarity and Limb Patterning

Zeidler, M. P., Perrimon, N., & Strutt, D. I. (2000) · Developmental Biology · doi:10.1006/dbio.2000.9940 · Cited by 134 · see citing works

A Drosophila PIAS homologue negatively regulates stat92E

Betz, A., Lampen, N., Martinek, S., Young, M. W., & Darnell, J. E., Jr. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.171302098 · Cited by 132 · see citing works

Evidence for positional differentiation of prestalk cells and for a morphogenetic gradient in dictyostelium

Early, A. E., Abe, T., & Williams, J. G. (1995) · Cell · doi:10.1016/0092-8674(95)90237-6 · Cited by 131 · see citing works

Evolution and genetics

Morgan, T. H. (1925) · Princeton University Press eBooks · doi:10.5962/bhl.title.4527 · Cited by 130 · see citing works

The Janus kinase family of protein tyrosine kinases and their role in signaling

Yeh, T. C., & Pellegrini, S. (1999) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050392 · Cited by 126 · see citing works

Cloning and expression of Drosophila SOCS36E and its potential regulation by the JAK/STAT pathway

Karsten, P., Häder, S., & Zeidler, M. P. (2002) · Mechanisms of Development · doi:10.1016/s0925-4773(02)00216-2 · Cited by 122 · see citing works

Zebrafishstat3 is expressed in restricted tissues during embryogenesis andstat1 rescues cytokine signaling in aSTAT1-deficient human cell line

Oates, A. C., Patrik, W., Pratt, S. J. P., Paw, B. H., Johnson, S. L., Ho, R. K., Postlethwait, J. H., Zon, L. I., & Wilks, A. F. (1999) · Developmental Dynamics · doi:10.1002/(sici)1097-0177(199908)215:4 · Cited by 121 · see citing works

l(1)hopscotch, a larval-pupal zygotic lethal with a specific maternal effect on segmentation in Drosophila

Perrimon, N., & Mahowald, A. P. (1986) · Developmental Biology · doi:10.1016/0012-1606(86)90070-9 · Cited by 110 · see citing works

Developmentally and spatially regulated activation of a Dictyostelium STAT protein by a serpentine receptor

Araki, T., Gamper, M., Early, A. E., Fukuzawa, M., Abe, T., Kawata, T., Kim, E. S., Firtel, R., & Williams, J. G. (1998) · The EMBO Journal · doi:10.1093/emboj/17.14.4018 · Cited by 110 · see citing works

The role of STATs in proliferation, differentiation, and apoptosis

Mui, A. (1999) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050394 · Cited by 101 · see citing works

Mosaic Analysis in the Drosophila Ovary Reveals a Common Hedgehog-Inducible Precursor Stage for Stalk and Polar Cells

Tworoger, M., Larkin, M. K., Bryant, Z. D., & Ruohola‐Baker, H. (1999) · Genetics · doi:10.1093/genetics/151.2.739 · Cited by 101 · see citing works

Polarity determination in the Drosophila eye

Strutt, H. L., & Strutt, D. I. (1999) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(99)80067-7 · Cited by 88 · see citing works

Tyrosine Phosphorylation-Independent Nuclear Translocation of a Dictyostelium STAT in Response to DIF Signaling

Fukuzawa, M., Araki, T., Adrian, I., & Williams, J. G. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00222-2 · Cited by 86 · see citing works

Gene Duplication of Zebrafish JAK2 Homologs Is Accompanied by Divergent Embryonic Expression Patterns: Only jak2a Is Expressed During Erythropoiesis

Oates, A. C., Brownlie, A., Pratt, S. J. P., Irvine, D. V., Liao, E. C.-W., Paw, B. H., Dorian, K. J., Johnson, S. L., Postlethwait, J. H., Zon, L. I., et al. (1999) · Blood · doi:10.1182/blood.v94.8.2622.420k39_2622_2636 · Cited by 82 · see citing works

Patterns of cell movement within the Dictyostelium slug revealed by cell type-specific, surface labeling of living cells

Abe, T., Early, A. E., Siegert, F., Weijer, C. J., & Williams, J. G. (1994) · Cell · doi:10.1016/0092-8674(94)90053-1 · Cited by 82 · see citing works

Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis

Mohanty, S., Jermyn, K. A., Early, A. E., Kawata, T., Aubry, L., Ceccarelli, A., Schaap, P., Williams, J. G., & Firtel, R. (1999) · Development · doi:10.1242/dev.126.15.3391 · Cited by 79 · see citing works

An extracellular activator of the Drosophila JAK/STAT pathway is a sex-determination signal element

Sefton, L., Timmer, J. R., Zhang, Y., Béranger, F., & Cline, T. W. (2000) · Nature · doi:10.1038/35016119 · Cited by 78 · see citing works

Study of the Posterior Spiracles of Drosophila as a Model to Understand the Genetic and Cellular Mechanisms Controlling Morphogenesis

Hu, N., & Hombría, J. C. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9391 · Cited by 78 · see citing works

Physiological significance of STAT proteins: investigations through gene disruption in vivo

Levy, D. (1999) · Cellular and Molecular Life Sciences (CMLS) · doi:10.1007/s000180050395 · Cited by 75 · see citing works

Cell migration in invertebrates: clues from border and distal tip cells

Lehmann, R. (2001) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00217-3 · Cited by 71 · see citing works

The JAK-STAT pathway in Drosophila

Hou, X. S. (1997) · Trends in Genetics · doi:10.1016/s0168-9525(97)01006-8 · Cited by 71 · see citing works

Fruit fly “leukemia”

Dearolf, C. R. (1998) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/s0304-419x(97)00031-0 · Cited by 65 · see citing works

The Hopscotch Jak kinase requires the Raf pathway to promote blood cell activation and differentiation in Drosophila

Luo, H., Rose, P., Roberts, T. M., & Dearolf, C. R. (2002) · Molecular Genetics and Genomics · doi:10.1007/s00438-001-0632-7 · Cited by 54 · see citing works

The JAK/STAT Signaling Pathway Is Required for the Initial Choice of Sexual Identity in Drosophila melanogaster

Jinks, T., Polydorides, A. D., Calhoun, G., & Schedl, P. D. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80451-7 · Cited by 53 · see citing works

Jak1 kinase is required for cell migrations and anterior specification in zebrafish embryos

Conway, G. C., Margoliath, A., Wong-Madden, S., Roberts, R. J., & Gilbert, W. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.7.3082 · Cited by 53 · see citing works

STAM/EAST/Hbp adapter proteins – integrators of signalling pathways

Lohi, O., & Lehto, V.-P. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)03079-4 · Cited by 46 · see citing works

The Drosophila Jak Kinase Hopscotch Is Required for Multiple Developmental Processes in the Eye

Luo, H., Asha, H. S., Kockel, L., Parke, T., Mlodzik, M., & Dearolf, C. R. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9390 · Cited by 45 · see citing works

Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter sitePreprint

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The Drosophila STAM gene homolog is in a tight gene cluster, and its expression correlates to that of the adjacent gene ial

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Transcriptomic responses to environmental temperature by turtles with temperature-dependent and genotypic sex determination assessed by RNAseq inform the genetic architecture of embryonic gonadal development

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Macrophage polarization in tissue fibrosis

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Contribution of Wound-Associated Cells and Mediators in Orchestrating Gastrointestinal Mucosal Wound Repair

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Cooperative Regulation of the Induction of the Novel Antibacterial Listericin by Peptidoglycan Recognition Protein LE and the JAK-STAT Pathway

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Repression of Wasp by JAK/STAT signalling inhibits medial actomyosin network assembly and apical cell constriction in intercalating epithelial cells

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Windpipe Controls Drosophila Intestinal Homeostasis by Regulating JAK/STAT Pathway via Promoting Receptor Endocytosis and Lysosomal Degradation

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Erythropoietin promotes survival and regeneration of insect neurons in vivo and in vitro

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The identification of transcription factors expressed in the notochord of Ciona intestinalis adds new potential players to the brachyury gene regulatory network

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Organ-specific transcriptome response of the small brown planthopper toward rice stripe virus

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SERPINE 1 expression discriminates site‐specific metastasis in human melanoma

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STAT1 activation regulates proliferation and differentiation of renal progenitors

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