The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Mitochondrial Genome Evolution and the Origin of Eukaryotes
Abstract
▪ Abstract Recent results from ancestral (minimally derived) protists testify to the tremendous diversity of the mitochondrial genome in various eukaryotic lineages, but also reinforce the view that mitochondria, descendants of an endosymbiotic α-Proteobacterium, arose only once in evolution. The serial endosymbiosis theory, currently the most popular hypothesis to explain the origin of mitochondria, postulates the capture of an α-proteobacterial endosymbiont by a nucleus-containing eukaryotic host resembling extant amitochondriate protists. New sequence data have challenged this scenario, instead raising the possibility that the origin of the mitochondrion was coincident with, and contributed substantially to, the origin of the nuclear genome of the eukaryotic cell. Defining more precisely the α-proteobacterial ancestry of the mitochondrial genome, and the contribution of the endosymbiotic event to the nuclear genome, will be essential for a full understanding of the origin and evolution of the eukaryotic cell as a whole.
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Cites
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An ancestral mitochondrial DNA resembling a eubacterial genome in miniature
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Self-citationThe Endosymbiont Hypothesis Revisited
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Self-citationHow good are deep phylogenetic trees?
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Cited by
Orthologs, Paralogs, and Evolutionary Genomics
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Horizontal gene transfer in prokaryotes: Quantification and classification
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Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia
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Metadata
- Authors
- Lang, B. F., Gray, M. W., & Burger, G.
- Venue
- Annual Review of Genetics
- Publisher
- Annual Reviews
- Published
- 1999-12
- Volume
- 33
- Issue
- 1
- Pages
- 351-397
- ISSN
- 0066-4197 (ISSN-L)
- 1545-2948
- OpenAlex
- W2116817481
- Cited by
- 725
- References
- 10
- FWCI
- 1.58
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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