The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Cell Cycle Regulation of DNA Replication
Open accessAbstract
Eukaryotic DNA replication is regulated to ensure all chromosomes replicate once and only once per cell cycle. Replication begins at many origins scattered along each chromosome. Except for budding yeast, origins are not defined DNA sequences and probably are inherited by epigenetic mechanisms. Initiation at origins occurs throughout the S phase according to a temporal program that is important in regulating gene expression during development. Most replication proteins are conserved in evolution in eukaryotes and archaea, but not in bacteria. However, the mechanism of initiation is conserved and consists of origin recognition, assembly of prereplication (pre-RC) initiative complexes, helicase activation, and replisome loading. Cell cycle regulation by protein phosphorylation ensures that pre-RC assembly can only occur in G1 phase, whereas helicase activation and loading can only occur in S phase. Checkpoint regulation maintains high fidelity by stabilizing replication forks and preventing cell cycle progression during replication stress or damage.
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Cites
Cell-cycle checkpoints and cancer
Kastan, M. B., & Bartek, J. (2004) · Nature · doi:10.1038/nature03097 · Cited by 2,836
Byun, T. S., Pacek, M., Yee, M.-C., Walter, J. C., & Cimprich, K. A. (2005) · Genes & Development · doi:10.1101/gad.1301205 · Cited by 767
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
Ira, G., Pellicioli, A., Balijja, A., Wang, X., Fiorani, S., Carotenuto, W., Liberi, G., Bressan, D., Wan, L., Hollingsworth, N. M., et al. (2004) · Nature · doi:10.1038/nature02964 · Cited by 722
Regulation of RAD53 by the ATM -Like Kinases MEC1 and TEL1 in Yeast Cell Cycle Checkpoint Pathways
Sanchez, Y., Desany, B. A., Jones, W. J., Liu, Q., Wang, B., & Elledge, S. J. (1996) · Science · doi:10.1126/science.271.5247.357 · Cited by 585
Ellison, V., & Stillman, B. (2003) · PLoS Biology · doi:10.1371/journal.pbio.0000033 · Cited by 363
Did DNA replication evolve twice independently?
Leipe, D. D., Aravind, L., & Koonin, E. V. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.17.3389 · Cited by 351
BCR/ABL translocates to the nucleus and disrupts an ATR-dependent intra-S phase checkpoint
Dierov, J., Dierova, R., & Carroll, M. (2004) · Cancer Cell · doi:10.1016/s1535-6108(04)00056-x · Cited by 117
Cited by
Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS Proteins
Ilves, I., Petojevic, T., Pesavento, J. J., & Botchan, M. R. (2010) · Molecular Cell · doi:10.1016/j.molcel.2009.12.030 · Cited by 548
Evrin, C., Clarke, P., Zech, J., Lurz, R., Sun, J., Uhle, S., Li, H., Stillman, B., & Speck, C. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911500106 · Cited by 536
Ibarra, A., Schwob, E., & Méndez, J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803978105 · Cited by 503
Understanding nucleosome dynamics and their links to gene expression and DNA replication
Lai, W. K. M., & Pugh, B. F. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.47 · Cited by 495
Conserved nucleosome positioning defines replication origins
Eaton, M. L., Galani, K., Kang, S., Bell, S. P., & MacAlpine, D. M. (2010) · Genes & Development · doi:10.1101/gad.1913210 · Cited by 384
Metadata
- Authors
- Sclafani, R. A., & Holzen, T. M.
- Venue
- Annual Review of Genetics
- Publisher
- Annual Reviews
- Published
- 2007-12-01
- Volume
- 41
- Issue
- 1
- Pages
- 237-280
- ISSN
- 0066-4197 (ISSN-L)
- 1545-2948
- OpenAlex
- W2121980126
- Cited by
- 450
- References
- 7
- FWCI
- 1.85
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
