The DOI matches its Crossref record; 134 of the 134 references it cites were found in a registry or an index.
Transgenerational Epigenetic Effects
Abstract
Transgenerational epigenetic effects include all processes that have evolved to achieve the nongenetic determination of phenotype. There has been a long-standing interest in this area from evolutionary biologists, who refer to it as non-Mendelian inheritance. Transgenerational epigenetic effects include both the physiological and behavioral (intellectual) transfer of information across generations. Although in most cases the underlying molecular mechanisms are not understood, modifications of the chromosomes that pass to the next generation through gametes are sometimes involved, which is called transgenerational epigenetic inheritance. There is a trend for those outside the field of molecular biology to assume that most cases of transgenerational epigenetic effects are the result of transgenerational epigenetic inheritance, in part because of a misunderstanding of the terms. Unfortunately, this is likely to be far from the truth.
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Cites
Epigenetic programming by maternal behavior
Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience · doi:10.1038/nn1276 · Cited by 6,177
Liu, D., Diorio, J., Tannenbaum, B., Caldji, C., Francis, D., Freedman, A., Sharma, S., Pearson, D., Plotsky, P. M., & Meaney, M. J. (1997) · Science · doi:10.1126/science.277.5332.1659 · Cited by 3,170
The development of Drosophila melanogaster
Ingham, P. (1994) · Trends in Genetics · doi:10.1016/0168-9525(90)90017-z · Cited by 3,149
Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility
Anway, M. D., Cupp, A. S., Uzumcu, M., & Skinner, M. K. (2005) · Science · doi:10.1126/science.1108190 · Cited by 2,563
Herbst, A. L., Ulfelder, H., & Poskanzer, D. C. (1971) · New England Journal of Medicine · doi:10.1056/nejm197104222841604 · Cited by 2,520
The Growth of Biological Thought: Diversity, Evolution, and Inheritance
Mayr, E. (1982) · CERN Document Server (European Organization for Nuclear Research) · Cited by 2,295
Hsp90 as a capacitor for morphological evolution
Rutherford, S. L., & Lindquist, S. (1998) · Nature · doi:10.1038/24550 · Cited by 2,270
Transposable elements: targets for early nutritional effects on epigenetic gene regulation
Waterland, R. A., & Jirtle, R. L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5293-5300.2003 · Cited by 2,019
Nongenomic Transmission Across Generations of Maternal Behavior and Stress Responses in the Rat
Francis, D., Diorio, J., Liu, D., & Meaney, M. J. (1999) · Science · doi:10.1126/science.286.5442.1155 · Cited by 1,965
Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in Arabidopsis
Zhang, X., Yazaki, J., Sundaresan, A., Cokus, S., Chan, S. W.-L., Chen, H., Henderson, I. R., Shinn, P., Pellegrini, M., Jacobsen, S. E., et al. (2006) · Cell · doi:10.1016/j.cell.2006.08.003 · Cited by 1,815
Cited by
Histone methylation: a dynamic mark in health, disease and inheritance
Greer, E. L., & Shi, Y. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3173 · Cited by 2,241
Early Developmental Conditioning of Later Health and Disease: Physiology or Pathophysiology?
Hanson, M. A., & Gluckman, P. D. (2014) · Physiological Reviews · doi:10.1152/physrev.00029.2013 · Cited by 1,188
Deans, C., & Maggert, K. A. (2015) · Genetics · doi:10.1534/genetics.114.173492 · Cited by 554
Disruption of histone methylation in developing sperm impairs offspring health transgenerationally
Siklenka, K., Erkek, S., Godmann, M., Lambrot, R., McGraw, S., Lafleur, C., Cohen, T., Xia, J., Suderman, M., Hallett, M., et al. (2015) · Science · doi:10.1126/science.aab2006 · Cited by 521
Babenko, O., Kovalchuk, I., & Metz, G. A. S. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.11.013 · Cited by 513
Metadata
- Authors
- Youngson, N. A., & Whitelaw, E.
- Venue
- Annual Review of Genomics and Human Genetics
- Publisher
- Annual Reviews
- Published
- 2008-09-01
- Volume
- 9
- Issue
- 1
- Pages
- 233-257
- ISSN
- 1527-8204 (ISSN-L)
- 1545-293X
- OpenAlex
- W2127456840
- Cited by
- 580
- References
- 134
- FWCI
- 2.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- Youngson, N. A., & Whitelaw, E. (2008). Transgenerational Epigenetic Effects. Annual Review of Genomics and Human Genetics. https://doi.org/10.1146/annurev.genom.9.081307.164445
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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