The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Control of Apoptosis in the Immune System: Bcl-2, BH3-Only Proteins and More
Abstract
Apoptotic cell death plays a critical role in the development and functioning of the immune system. During differentiation, apoptosis weeds out lymphocytes lacking useful antigen receptors and those expressing dangerous ones. Lymphocyte death is also involved in limiting the magnitude and duration of immune responses to infection. In this review, we describe the role of the Bcl-2 protein family, and to a lesser extent that of death receptors (members of the tumor necrosis factor receptor family with a death domain), in the control of lymphoid and myeloid cell survival. We also consider the pathogenic consequences of failure of apoptosis in the immune system.
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Cites
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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
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Cited by
The many roles of FAS receptor signaling in the immune system
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Self-citationSignalling strength determines proapoptotic functions of STING
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Protein Kinase C-θ Is an Early Survival Factor Required for Differentiation of Effector CD8+ T Cells
Barouch-Bentov, R., Lemmens, E. E., Hu, J., Janssen, E. M., Droin, N. M., Song, J., Schoenberger, S. P., & Altman, A. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.8.5126 · Cited by 64
Metadata
- Authors
- Marsden, V. S., & Strasser, A.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 2003-04
- Volume
- 21
- Issue
- 1
- Pages
- 71-105
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2142314780
- Cited by
- 384
- References
- 9
- FWCI
- 2.94
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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