The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
B CELL IMMUNOBIOLOGY IN DISEASE: Evolving Concepts from the Clinic
Abstract
The pathogenic roles of B cells in autoimmune diseases occur through several mechanistic pathways that include autoantibodies, immune complexes, dendritic and T cell activation, cytokine synthesis, chemokine-mediated functions, and ectopic neolymphogenesis. Each of these pathways participate to different degrees in autoimmune diseases. The use of B cell–targeted and B cell subset–targeted therapies in humans is illuminating the mechanisms at work in a variety of human autoimmune diseases. In this review, we highlight some of these recent findings that provide insights into both murine models of autoimmunity and human autoimmune diseases.
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Cites
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Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis
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Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis
Hauser, S. L., Bar-Or, A., Comi, G., Giovannoni, G., Hartung, H.-P., Hemmer, B., Lublin, F., Montalban, X., Rammohan, K. W., Selmaj, K., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1601277 · Cited by 2,021
Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis
Montalban, X., Hauser, S. L., Kappos, L., Arnold, D. L., Bar-Or, A., Comi, G., de Seze, J., Giovannoni, G., Hartung, H.-P., Hemmer, B., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1606468 · Cited by 1,905
A guide to antigen processing and presentation
Pishesha, N., Harmand, T. J., & Ploegh, H. L. (2022) · Nature Reviews Immunology · doi:10.1038/s41577-022-00707-2 · Cited by 805
CD20+ B Cells: The Other Tumor-Infiltrating Lymphocytes
Nelson, B. H. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1001323 · Cited by 416
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“Most experimental data indicate that SCI autoantibodies can cause tissue damage; therefore, strategies to remove or deplete autoantibodies or suppress B-cell activation could be neuroprotective (Martin and Chan, 2006).”
Background
Metadata
- Authors
- Martin, F., & Chan, A. C.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 2006-04-01
- Volume
- 24
- Issue
- 1
- Pages
- 467-496
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2102697241
- Cited by
- 369
- References
- 9
- FWCI
- 1.90
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: B CELL IMMUNOBIOLOGY IN DISEASE: Evolving Concepts from the Clinic. https://app.cochat.ai/papers/10.1146/annurev.immunol.24.021605.090517
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- Martin, F., & Chan, A. C. (2006). B CELL IMMUNOBIOLOGY IN DISEASE: Evolving Concepts from the Clinic. Annual Review of Immunology. https://doi.org/10.1146/annurev.immunol.24.021605.090517
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
