The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Letting Sleeping dos Lie: Does Dormancy Play a Role in Tuberculosis?
Abstract
Mycobacterium tuberculosis, which causes tuberculosis, remains a major human public health threat. This is largely due to a sizeable reservoir of latently infected individuals, who may relapse into active disease decades after first acquiring the infection. Furthermore, patients have a very slow response to treatment of active disease. Latency and antibiotic tolerance are commonly taken as a proxy for dormancy, a stable nonreplicative state. However, latency is a clinical term that is solely defined by a lack of disease indicators. The actual state of the bacterium in human latency is not well understood. Here we evaluate the results of several in vitro models of dormancy and consider the applicability of various animal models for studying aspects of human latency and resistance to killing by antibiotics. Furthermore, we propose a model for the initiation of dormancy and resuscitation during infection.
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Cites
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Liu, P. T., Stenger, S., Li, H., Wenzel, L., Tan, B. H., Krutzik, S. R., Ochoa, M. T., Schauber, J., Wu, K., Meinken, C., et al. (2006) · Science · doi:10.1126/science.1123933 · Cited by 3,924
Persister cells, dormancy and infectious disease
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Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages
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Identification of nitric oxide synthase as a protective locus against tuberculosis
MacMicking, J. D., North, R. J., LaCourse, R., Mudgett, J. S., Shah, S. K., & Nathan, C. F. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.10.5243 · Cited by 1,180
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The Enduring Hypoxic Response of Mycobacterium tuberculosis
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Cited by
The challenge of new drug discovery for tuberculosis
Koul, A., Arnoult, E., Lounis, N., Guillemont, J., & Andries, K. (2011) · Nature · doi:10.1038/nature09657 · Cited by 1,042
Mycobacterium tuberculosis: success through dormancy
Gengenbacher, M., & Kaufmann, S. H. E. (2012) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2012.00331.x · Cited by 696
The immunological life cycle of tuberculosis
Ernst, J. D. (2012) · Nature Reviews Immunology · doi:10.1038/nri3259 · Cited by 577
Anti-tuberculosis treatment strategies and drug development: challenges and priorities
Dartois, V. A., & Rubin, E. J. (2022) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00731-y · Cited by 490
Self-citationFauvart, M., De Groote, V. N., & Michiels, J. (2011) · Journal of Medical Microbiology · doi:10.1099/jmm.0.030932-0 · Cited by 425
Metadata
- Authors
- Chao, M. C., & Rubin, E. J.
- Venue
- Annual Review of Microbiology
- Publisher
- Annual Reviews
- Published
- 2010-10-13
- Volume
- 64
- Issue
- 1
- Pages
- 293-311
- ISSN
- 0066-4227 (ISSN-L)
- 1545-3251
- OpenAlex
- W2152206032
- Cited by
- 214
- References
- 9
- FWCI
- 2.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chao, M. C., & Rubin, E. J. (2010). Letting Sleeping dos Lie: Does Dormancy Play a Role in Tuberculosis? Annual Review of Microbiology. https://doi.org/10.1146/annurev.micro.112408.134043
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
