The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.
The RNA Degradosome of Escherichia coli: An mRNA-Degrading Machine Assembled on RNase E
Abstract
The RNA degradosome of Escherichia coli is a multiprotein complex involved in the degradation of mRNA. The principal components are RNase E, PNPase, RhlB, and enolase. RNase E is a large multidomain protein with an N-terminal catalytic region and a C-terminal noncatalytic region that is mostly natively unstructured protein. The noncatalytic region contains sites for binding RNA and for protein-protein interactions with other components of the RNA degradosome. Several recent studies suggest that there are alternative forms of the RNA degradosome depending on growth conditions or other factors. These alternative forms appear to modulate RNase E activity in the degradation of mRNA. RNA degradosome-like complexes appear to be conserved throughout the Proteobacteria, but there is a surprising variability in composition that might contribute to the adaptation of these bacteria to the enormously wide variety of niches in which they live.
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Cites
Intrinsically unstructured proteins
Tompa, P. (2002) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(02)02169-2 · Cited by 2,050
Interaction network containing conserved and essential protein complexes in Escherichia coli
Butland, G., Peregrín-Alvarez, J. M., Li, J., Yang, W., Yang, X., Canadien, V., Starostine, A., Richards, D., Beattie, B., Krogan, N., et al. (2005) · Nature · doi:10.1038/nature03239 · Cited by 1,201
Bernstein, J. A., Khodursky, A. B., Lin, P.-H., Lin-Chao, S., & Cohen, S. N. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.112318199 · Cited by 857
Tanner, N. K., & Linder, P. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00329-x · Cited by 747
Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli
Massé, E., Escorcia, F. E., & Gottesman, S. (2003) · Genes & Development · doi:10.1101/gad.1127103 · Cited by 708
The Small RNA Regulators of Escherichia coli : Roles and Mechanisms
Gottesman, S. (2004) · Annual Review of Microbiology · doi:10.1146/annurev.micro.58.030603.123841 · Cited by 586
A DEAD-box RNA helicase in the Escherichia coli RNA degradosome
Py, B., Higgins, C. F., Krisch, H. M., & Carpousis, A. J. (1996) · Nature · doi:10.1038/381169a0 · Cited by 553
Self-citationMorita, T., Maki, K., & Aiba, H. (2005) · Genes & Development · doi:10.1101/gad.1330405 · Cited by 458
Dead-box proteins: a family affair—active and passive players in RNP-remodeling
Linder, P. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl468 · Cited by 453
Degradation of RNA in bacteria: comparison of mRNA and stable RNA
Deutscher, M. P. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkj472 · Cited by 447
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Strategies to Optimize Protein Expression in E. coli
Francis, D. M., & Page, R. (2010) · Current Protocols in Protein Science · doi:10.1002/0471140864.ps0524s61 · Cited by 272
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Rorbach, J., & Minczuk, M. (2012) · Biochemical Journal · doi:10.1042/bj20112208 · Cited by 118
Substrate Binding and Active Site Residues in RNases E and G
Garrey, S. M., Blech, M., Riffell, J. L., Hankins, J. S., Stickney, L. M., Diver, M., Hsu, Y.-H. R., Kunanithy, V., & Mackie, G. A. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.063263 · Cited by 56
Metadata
- Authors
- Carpousis, A. J.
- Venue
- Annual Review of Microbiology
- Publisher
- Annual Reviews
- Published
- 2007-10-01
- Volume
- 61
- Issue
- 1
- Pages
- 71-87
- ISSN
- 0066-4227 (ISSN-L)
- 1545-3251
- OpenAlex
- W2168702835
- Cited by
- 445
- References
- 62
- FWCI
- 3.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- Carpousis, A. J. (2007). The RNA Degradosome of Escherichia coli: An mRNA-Degrading Machine Assembled on RNase E. Annual Review of Microbiology. https://doi.org/10.1146/annurev.micro.61.080706.093440
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
