The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
RAB3 AND SYNAPTOTAGMIN: The Yin and Yang of Synaptic Membrane Fusion
Abstract
▪ Abstract Synaptic vesicle exocytosis occurs in consecutive steps: docking, which specifically attaches vesicles to the active zone; priming, which makes the vesicles competent for Ca 2+-triggered release and may involve a partial fusion reaction; and the final Ca 2+-regulated step that completes fusion. Recent evidence suggests that the critical regulation of the last step in the reaction is mediated by two proteins with opposite actions: synaptotagmin, a Ca 2+-binding protein that is essential for Ca 2+-triggered release and probably serves as the Ca 2+-sensor in fusion, and rab3, which limits the number of vesicles that can be fused as a function of Ca 2+ in order to allow a temporally limited, repeatable signal.
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Cites
The GTPase superfamily: conserved structure and molecular mechanism
Bourne, H. R., Sanders, D. A., & McCormick, F. (1991) · Nature · doi:10.1038/349117a0 · Cited by 3,392
Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse
Geppert, M., Goda, Y., Hammer, R. E., Li, C., Rosahl, T. W., Stevens, C. F., & Südhof, T. C. (1994) · Cell · doi:10.1016/0092-8674(94)90556-8 · Cited by 1,483
Self-citationSweeney, S. T., Broadie, K., Keane, J., Niemann, H., & O'Kane, C. J. (1995) · Neuron · doi:10.1016/0896-6273(95)90290-2 · Cited by 938
A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.
Davletov, B. A., & Südhof, T. C. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74326-9 · Cited by 480
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Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909
The synapsins: Key actors of synapse function and plasticity
Cesca, F., Baldelli, P., Valtorta, F., & Benfenati, F. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.04.006 · Cited by 654
RIM Binding Proteins (RBPs) Couple Rab3-Interacting Molecules (RIMs) to Voltage-Gated Ca2+ Channels
Hibino, H., Pironkova, R., Onwumere, O., Vologodskaia, M., Hudspeth, A. J., & Lesage, F. (2002) · Neuron · doi:10.1016/s0896-6273(02)00667-0 · Cited by 309
The RIM/NIM Family of Neuronal C2 Domain Proteins
Wang, Y., Sugita, S., & Südhof, T. C. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m909008199 · Cited by 243
Self-citationStatins and the Brain: More than Lipid Lowering Agents?
Fracassi, A., Marangoni, M., Rosso, P., Pallottini, V., Fioramonti, M., Siteni, S., & Segatto, M. (2018) · Current Neuropharmacology · doi:10.2174/1570159x15666170703101816 · Cited by 116
Metadata
- Authors
- Geppert, M., & Südhof, T. C.
- Venue
- Annual Review of Neuroscience
- Publisher
- Annual Reviews
- Published
- 1998-03
- Volume
- 21
- Issue
- 1
- Pages
- 75-95
- ISSN
- 0147-006X (ISSN-L)
- 1545-4126
- OpenAlex
- W2108632260
- Cited by
- 254
- References
- 4
- FWCI
- 1.98
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
