The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
The Role of Notch in Promoting Glial and Neural Stem Cell Fates
Abstract
▪ Abstract The Notch signaling pathway has long been known to influence cell fate in the developing nervous system. However, this pathway has generally been thought to inhibit the specification of certain cell types in favor of others, or to simply maintain a progenitor pool. Recently, this view has been challenged by numerous studies suggesting that Notch may play an instructive role in promoting glial development. This work has inspired a new look at the role of Notch signaling in specifying cell fate. It has also prompted further consideration of the emerging view that in some contexts glia may be multipotent progenitors. This review examines the role of Notch during gliogenesis in both fruit flies and vertebrates, as well as evidence in vertebrates that some glia may be stem cells.
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Cites
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898
Specification of Cerebral Cortical Areas
Rakic, P. (1988) · Science · doi:10.1126/science.3291116 · Cited by 3,127 · cited 1×
“These cells have traditionally been thought to provide a migratory scaffold along which newly generated neurons migrate from the VZ to postmitotic areas (Rakic 1988, 1995).”
BackgroundIsolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage
Malatesta, P., Hartfuss, E., & Götz, M. (2000) · Development · doi:10.1242/dev.127.24.5253 · Cited by 1,157
Cited by
The Glial Nature of Embryonic and Adult Neural Stem Cells
Kriegstein, A., & Alvarez-Buylla, A. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135600 · Cited by 2,475
Adult neurogenesis: from precursors to network and physiology
Abrous, D. N., Koehl, M., & Le Moal, M. (2005) · Physiological Reviews · doi:10.1152/physrev.00055.2003 · Cited by 971
Astrocytes and disease: a neurodevelopmental perspective
Molofsky, A. V., Krenick, R., Ullian, E., Tsai, H.-H., Deneen, B., Richardson, W. D., Barres, B. A., & Rowitch, D. H. (2012) · Genes & Development · doi:10.1101/gad.188326.112 · Cited by 682
Notch Pathway Inhibition Depletes Stem-like Cells and Blocks Engraftment in Embryonal Brain Tumors
Fan, X., Matsui, W., Khaki, L., Stearns, D., Chun, J., Li, Y.-M., & Eberhart, C. G. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-0858 · Cited by 615
Notch signaling in the mammalian central nervous system: insights from mouse mutants
Yoon, K., & Gaiano, N. (2005) · Nature Neuroscience · doi:10.1038/nn1475 · Cited by 587
Self-citation
Metadata
- Authors
- Gaiano, N., & Fishell, G.
- Venue
- Annual Review of Neuroscience
- Publisher
- Annual Reviews
- Published
- 2002-03
- Volume
- 25
- Issue
- 1
- Pages
- 471-490
- ISSN
- 0147-006X (ISSN-L)
- 1545-4126
- OpenAlex
- W2097546542
- Cited by
- 602
- References
- 3
- FWCI
- 2.32
- Type
- journal article
- Language
- en
- Open access
- closed
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