The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Orbitofrontal Cortex and Its Contribution to Decision-Making
Abstract
Damage to orbitofrontal cortex (OFC) produces an unusual pattern of deficits. Patients have intact cognitive abilities but are impaired in making everyday decisions. Here we review anatomical, neuropsychological, and neurophysiological evidence to determine the neuronal mechanisms that might underlie these impairments. We suggest that OFC plays a key role in processing reward: It integrates multiple sources of information regarding the reward outcome to derive a value signal. In effect, OFC calculates how rewarding a reward is. This value signal can then be held in working memory where it can be used by lateral prefrontal cortex to plan and organize behavior toward obtaining the outcome, and by medial prefrontal cortex to evaluate the overall action in terms of its success and the effort that was required. Thus, acting together, these prefrontal areas can ensure that our behavior is most efficiently directed towards satisfying our needs.
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Cites
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Neural systems of reinforcement for drug addiction: from actions to habits to compulsion
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The Neural Basis of Decision Making
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Cited by
A framework for studying the neurobiology of value-based decision making
Rangel, A., Camerer, C., & Montague, P. R. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2357 · Cited by 2,184
Inhibition and impulsivity: behavioral and neural basis of response control
Bari, A., & Robbins, T. W. (2013) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.06.005 · Cited by 1,921
Neural Mechanisms for Interacting with a World Full of Action Choices
Cisek, P., & Kalaska, J. F. (2010) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135409 · Cited by 1,543
Visual fixations and the computation and comparison of value in simple choice
Krajbich, I., Armel, C., & Rangel, A. (2010) · Nature Neuroscience · doi:10.1038/nn.2635 · Cited by 1,408
Affective neuroscience of pleasure: reward in humans and animals
Berridge, K. C., & Kringelbach, M. L. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1099-6 · Cited by 1,254
Metadata
- Authors
- Wallis, J. D.
- Venue
- Annual Review of Neuroscience
- Publisher
- Annual Reviews
- Published
- 2007-07-01
- Volume
- 30
- Issue
- 1
- Pages
- 31-56
- ISSN
- 0147-006X (ISSN-L)
- 1545-4126
- OpenAlex
- W2115964617
- Cited by
- 900
- References
- 43
- FWCI
- 2.33
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
