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Vitamin B 12 -Folate Interrelationships
Abstract
The studies discussed in this review support the view that biochemical and clinical symptoms common to both folate and vitamin B12 deficiency are due to the induction of a functional folate deficiency, which in turn is induced by cobalamin deprivation. The interrelationship between these two vitamins is best explained by the methyl trap hypothesis stating that vitamin B12 deficiency can lead to lowered levels of methionine synthetase, which results in a functional folate deficiency by trapping an increased proportion of folate as the 5-methyl derivative. In addition, as 5-methyl-H4PteGlu is a poor substrate for folylpolyglutamate synthetase, there is a decreased synthesis of folylpolyglutamates and consequently a decreased retention of folates by tissues. The real folate deficiency that ensues because of decreased tissue folate levels is probably as important physiologically as the functional deficiency caused by the methyl trap. The sparing effect of methionine can be explained by adenosylmethionine inhibition of methylenetetrahydrofolate reductase, which would prevent the buildup of 5-methyl-H4PteGlun. A deficiency in vitamin B12 would not, in itself, be sufficient to cause a disturbance in folate metabolism. The deficiency would have to result in lowered methyltransferase levels before any such disturbance would be manifest.
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“Vitamin B-12 is also important for intracellular energy production and the generation of methionine, which is needed to produce neurotransmitters and myelin (7).”
From Vitamin B-12 status in infancy is positively associated with development and cognitive functioning 5 y later in Nepalese children (2017) · cites this paper as [7]
Citations
Cites
Deranged DNA Synthesis by Bone Marrow from Vitamin B12‐Deficient Humans*
Metz, J., Kelly, A., Swett, V. C., Waxman, S., & Herbert, V. D. (1968) · British Journal of Haematology · doi:10.1111/j.1365-2141.1968.tb00364.x · Cited by 227
The regulation of folate and methionine metabolism
Krebs, H. A., Hems, R., & Tyler, B. (1976) · Biochemical Journal · doi:10.1042/bj1580341 · Cited by 221
METHANOL POISONING: ROLE OF FORMATE METABOLISM IN THE MONKEY
McMartin, K. E., Martin-Amat, G., MAKAR, A. B., & Tephly, T. R. (1977) · Elsevier eBooks · doi:10.1016/b978-0-12-691402-3.50045-7 · Cited by 131
The effect of methotrexate on levels of dUTP in animal cells.
Goulian, M., Bleile, B., & Tseng, B. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)70353-6 · Cited by 125
Amos, R. J., Hinds, C., AMESS, J. A. L., & Mollin, D. L. (1982) · The Lancet · doi:10.1016/s0140-6736(82)90808-x · Cited by 98
Inactivation of Methionine Synthetase by Nitrous Oxide in Mice
Koblin, D. D., Watson, J. E., Deady, J. E., Stokstad, E. L. R., & Eger, E. I. (1981) · Anesthesiology · doi:10.1097/00000542-198104000-00012 · Cited by 89
Ayusawa, D., Shimizu, K., Koyama, H., Takeishi, K., & Seno, T. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44196-2 · Cited by 86
Congenital defects in folate utilization
Arakawa, T. (1970) · The American Journal of Medicine · doi:10.1016/0002-9343(70)90009-4 · Cited by 83
MacKenzie, R. E., & Baugh, C. M. (1980) · Biochimica et Biophysica Acta (BBA) - Enzymology · doi:10.1016/0005-2744(80)90054-6 · Cited by 78
Methanol poisoning and formate oxidation in nitrous oxide-treated rats.
Eells, J. T., MAKAR, A. B., Noker, P. E., & Tephly, T. R. (1981) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)32491-2 · Cited by 66
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Voss, K. A., Riley, R. T., & Waes, J. G. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-382032-7.10053-0 · Cited by 10
Metabolism of Methionine and Methionine Hydroxy Analogue by Porcine Kidney Fibroblasts
Schreiner, C. L., & Jones, E. E. (1987) · Journal of Nutrition · doi:10.1093/jn/117.9.1541 · Cited by 10
Vallet, J. L., Smith, T. P. L., Sonstegard, T. S., Pearson, P., Christenson, R. K., & Klemcke, H. G. (1999) · Biology of Reproduction · doi:10.1095/biolreprod61.2.372 · Cited by 10
Dolutegravir and Folic Acid Interaction during Neural System Development in Zebrafish Embryos
Zizioli, D., Quirós-Roldán, E., Ferretti, S., Mignani, L., Tiecco, G., Monti, E., Castelli, F., & Zanella, I. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25094640 · Cited by 9
1 H and 13 C NMR and FTIR Spectroscopic Analysis of Formic Acid Dissociation Dynamics in Water
Telfah, A., Al‐Bataineh, Q. M., Al‐Essa, K., Al‐Sawalmih, A., Telfah, M., Gogiashvili, M., Bahti, A., Majer, G., & Hergenröder, R. (2024) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.4c04701 · Cited by 9
Kirsch, S. H., Herrmann, W., Kruse, V., Eckert, R., Gräber, S., Geisel, J., & Obeid, R. (2014) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2014-0540 · Cited by 9
Elimination of human folypolyglutamate synthetase alters programming and plasticity of somatic cells
Srivastava, A. C., Thompson, Y., Singhal, J., Stellern, J., Srivastava, A., Du, J., O'Connor, T. R., & Riggs, A. D. (2019) · The FASEB Journal · doi:10.1096/fj.201901721r · Cited by 9
Merrill, A. H., Foltz, A. T., & McCormick, D. B. (1991) · Springer eBooks · doi:10.1007/978-1-4757-9561-5_12 · Cited by 9
Lewis, S. M., Ullrey, D. E., Barnard, D. E., & Knapka, J. J. (2006) · Elsevier eBooks · doi:10.1016/b978-012074903-4/50012-1 · Cited by 8
Inhibition of Cellular Uptake of Folate by Blocking Synthesis of the Membrane Folate Receptor
Wolf, G. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1998.tb01700.x · Cited by 8
Kim, J. G., & Vallet, J. L. (2004) · Biology of Reproduction · doi:10.1095/biolreprod.104.031088 · Cited by 8
Vitamin B12 supplementation for growth, development, and cognition in children
Leal, C. G., Molina, X. E. P., Venkatramanan, S., Williams, J. L., Kuriyan, R., Crider, K. S., & Finkelstein, J. L. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd015264 · Cited by 7
Jungert, A., & Neuhäuser‐Berthold, M. (2018) · European Journal of Clinical Nutrition · doi:10.1038/s41430-018-0367-8 · Cited by 7
Is folic acid supplementation to food benefit or risk for human health?
Bjelaković, G., Stojanović, I. R., Jevtović−Stoimenov, T., Bjelaković, L., Kamenov, Β., Pavlovic, D. D., Kocic, G. M., Sokolovic, D. T., Bašić, J., & Bjelakovic, G. B. (2013) · Pteridines · doi:10.1515/pterid-2013-0024 · Cited by 7
Li, P., Huang, L., Zheng, Y., Pan, X., Peng, R., Jiang, Y., Finnell, R. H., Li, H., Qiao, B., & Wang, H.-Y. (2017) · Oncotarget · doi:10.18632/oncotarget.19377 · Cited by 7
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Chen, X., Yang, J., Zhang, H., Huang, Y., Cao, Y., Yan, S., Zong, G., Zheng, Y., Wang, X., & Yuan, C. (2022) · European Journal of Nutrition · doi:10.1007/s00394-022-02825-y · Cited by 7
Jungert, A., Zenke‐Philippi, C., & Neuhäuser‐Berthold, M. (2020) · Nutrition Journal · doi:10.1186/s12937-020-00576-2 · Cited by 7
Heyden, K. E., Malysheva, O., MacFarlane, A. J., Brody, L. C., & Field, M. S. (2024) · Journal of Nutrition · doi:10.1016/j.tjnut.2024.09.021 · Cited by 6
Scoping review of micronutrient imbalances, clinical manifestations, and interventions
English, K. J., Uwibambe, C., Daniels, P., & Dzukey, E. (2025) · World Journal of Methodology · doi:10.5662/wjm.v15.i4.107664 · Cited by 7
Analysis of spermatogenesis and fertility in adult mice with a hypomorphic mutation in the Mtrr gene
Blake, G. E. T., Hall, J. F., Petkovic, G., & Watson, E. D. (2019) · Reproduction Fertility and Development · doi:10.1071/rd19064 · Cited by 6
Amplification of ribosomal DNA in the nucleolus of vitamin B12-deficient Euglena cells
Bertaux, O., Mederic, C., & Valencia, R. (1991) · Experimental Cell Research · doi:10.1016/0014-4827(91)90507-q · Cited by 6
Nakao, M., Nozomi, K. O. N. O., ADACHI, S., Ebara, S., Adachi, T., Miura, T., Yamaji, R., Inui, H., & Nakano, Y. (2006) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.52.168 · Cited by 6
Adverse Metabolic Consequences of Nutritional Support: Micronutrients
Husami, T., & Abumrad, N. N. (1986) · Surgical Clinics of North America · doi:10.1016/s0039-6109(16)44040-5 · Cited by 6
Min, H., & Kim, M. (2009) · Journal of Nutrition and Health · doi:10.4163/kjn.2009.42.5.423 · Cited by 5
Voss, K. A., Riley, R. T., Gardner, N. M., & Waes, J. G. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804239-7.00047-0 · Cited by 5
SECOND-TRIMESTER BIOCHEMICAL SCREENING
Evans, M. I., O’Brien, J. E., Dvorin, E., Harrison, H. H., & Bui, T. (2001) · Clinics in Perinatology · doi:10.1016/s0095-5108(05)70084-1 · Cited by 5
Brasil, F. B., Amarante, L. H., & de Oliveira, M. R. (2017) · Revista Brasileira de Saúde Materno Infantil · doi:10.1590/1806-93042017000100002 · Cited by 5
[6S]-5-Methyltetrahydrofolate enhances folate status in rats fed growing-up milk
Pérez-Conesa, D., Haro‐Vicente, J. F., Romero, F., & Ros, G. (2009) · European Journal of Nutrition · doi:10.1007/s00394-009-0022-1 · Cited by 5
The effect of methionine on methotrexate metabolism in rat hepatocytes in monolayer culture
Rhee, M. S., Johnson, T. B., Priest, D. G., & Galivan, J. H. (1989) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/0167-4889(89)90198-5 · Cited by 5
Evans, M. I., Krivchenia, E. L., & Yaron, Y. (2002) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1053/beog.2002.0330 · Cited by 5
Metabolism and Urinary Excretion of Folates in Hypothyroid Rats.
Nair, C. P. P., Viswanathan, G., & NORONHA, J. M. (1992) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.13.87 · Cited by 5
Boden, G. H., Scapa, E. F., Kanno, K., Cohen, D. E., Brosnan, M. E., Brosnan, J. T., Pessayre, D., Roy‐Chowdhury, N., Lu, Y., Roy‐Chowdhury, J., et al. (2007) · Wiley eBooks · doi:10.1002/9780470691861.ch2c · Cited by 5
El-Mallah, C. A., Yarparvar, A., Galetti, V., Obeid, O., Boutros, M., Safadi, G., ZeinEddine, R., Ezzeddine, N. E. H., Kouzeiha, M., Kobayter, D., et al. (2025) · Nutrients · doi:10.3390/nu17050804 · Cited by 6
Vitamin B12 supplementation for growth, development, and cognition in children
Larvie, D. Y., Leal, C. G., Venkatramanan, S., Molina, X. E. P., Steel, L. B., Kuriyan, R., & Finkelstein, J. L. (2026) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd015264.pub2 · Cited by 4
Waes, J. G. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-89773-0.00047-3 · Cited by 4
Taneja, S., Chowdhury, R., Kvestad, I., Bhandari, N., & Strand, T. A. (2022) · British Journal Of Nutrition · doi:10.1017/s0007114522002343 · Cited by 4
Association of vitamin deficiency with the progression of anaemia
Urwa, H., Waheed, A., Naz, H., Shoaib, A. M., Saleem, K. M., & Muhammad, W. (2024) · The Egyptian Journal of Haematology · doi:10.4103/ejh.ejh_80_23 · Cited by 4
Coding sequence, genomic organization and expression of a folate binding protein gene in the rat
Sadasivan, E., Meng, Y., & Rothenberg, S. P. (2000) · Gene · doi:10.1016/s0378-1119(00)00262-6 · Cited by 4
Badiga, S., Siddiqui, N. R., Macaluso, M., Johanning, G. L., & Piyathilake, C. J. (2016) · Nutrition and Cancer · doi:10.1080/01635581.2016.1152388 · Cited by 4
Günter, T., & Demir, F. E. O. (2018) · Journal of Biological Education · doi:10.1080/00219266.2018.1469538 · Cited by 4
Goyal, A., Kumawat, M., Vashisth, M., Gill, P., Sing, I., & Dhaulakhandi, D. B. (2021) · Asian Journal of Neurosurgery · doi:10.4103/ajns.ajns_372_20 · Cited by 4
Structure of the genes for porcine endometrial secreted and membrane folate binding proteins
Vallet, J. L., Smith, T. P. L., Sonstegard, T. S., Heaton, M. P., & Fahrenkrug, S. C. (2001) · Domestic Animal Endocrinology · doi:10.1016/s0739-7240(01)00100-x · Cited by 4
E. L. Robert Stokstad (1913–1995)
Barry, S., & Carpenter Kenneth, J. (1997) · Journal of Nutrition · doi:10.1093/jn/127.2.199 · Cited by 4
A review on the relations between the vitamin status and cognitive performances
Franchi, F., Baio, G., Bolognesi, A. G., Braghieri, C., Luchetti, L., & Anzivino, F. (1998) · Archives of Gerontology and Geriatrics · doi:10.1016/s0167-4943(98)80030-7 · Cited by 4
Folate requirements and metabolism in alcoholic liver disease
Halsted, C. H. (1994) · Nutrition Research · doi:10.1016/s0271-5317(05)80302-1 · Cited by 4
3 Megaloblastic anaemia in the elderly
Parry, T. E. (1987) · Baillière s Clinical Haematology · doi:10.1016/s0950-3536(87)80005-7 · Cited by 4
Protozoological Approaches to the Cellular Basis of Mammalian Stress Repair
Hutner, S. H., & Marcus, S. L. (1987) · International review of cytology · doi:10.1016/s0074-7696(08)61704-0 · Cited by 4
Ginoudis, A., Ιωαννίδου, Ά., Pardali, D., Tsikna, A., & Polizopoulou, Z. S. (2024) · Metabolites · doi:10.3390/metabo14120657 · Cited by 3
Mshanga, N., Kassim, N., Sonto, S., Martin, H., Pirani, M., Moore, S. G., Auma, C. I., Kimanya, M. E., & Gong, Y. Y. (2025) · Maternal and Child Nutrition · doi:10.1111/mcn.70068 · Cited by 3
Rapid induction of vitamin B12 deficiency in Caenorhabditis elegans cultured in axenic medium
Tegegne, S., Jois, M., Flavel, M., Callahan, D. L., & Benheim, D. (2018) · Journal of Nutrition & Intermediary Metabolism · doi:10.1016/j.jnim.2018.08.001 · Cited by 3
One-carbon metabolism is required for epigenetic stability in the mouse placenta
Senner, C. E., Dong, Z., Prater, M., Branco, M. R., & Watson, E. D. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1209928 · Cited by 3
Solvik, B. S., Bakken, K. S., McCann, A., Ueland, P. M., Henjum, S., & Strand, T. A. (2024) · Journal of Nutritional Science · doi:10.1017/jns.2024.54 · Cited by 3
Amino acid changes in plasma and liver of cobalt‐deficient cattle
Stangl, G. I., Schwarz, F. J., & Kirchgeßner, M. (1998) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/j.1439-0396.1998.tb00498.x · Cited by 3
Placental expression of the membrane form of folate binding protein during pregnancy in swine
Kim, J. G., & Vallet, J. L. (2007) · Theriogenology · doi:10.1016/j.theriogenology.2007.01.016 · Cited by 3
Fumonisin, Folate, and Neural Tube Defects
Waes, J. G. (2010) · Elsevier eBooks · doi:10.1016/b978-0-08-046884-6.01519-0 · Cited by 3
Ozkilic, A., Çetin, A., Bayoğlu, B., Balcı, H., & Cengiz, M. (2016) · Turkish Journal of Biochemistry · doi:10.1515/tjb-2016-0151 · Cited by 3
Making Sense of Laboratory Tests of Folate Status: Folate Requirements to Sustain Normality
Herbert, V. D. (1989) · Springer eBooks · doi:10.1007/978-3-642-74364-1_8 · Cited by 3
Reuber, S., Kreuzer, M., & Kirchgeßner, M. (1993) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/j.1439-0396.1993.tb00302.x · Cited by 3
Neurotropic B vitamins effects: overview
Vertkin, A. L., Knorring, G. Y., & Aliev, Z. K. (2023) · Russian Medical Inquiry · doi:10.32364/2587-6821-2023-7-10-6 · Cited by 2
Bai, F., Wang, L., Liu, H., He, Y., & Wang, H. (2025) · Clinical Rheumatology · doi:10.1007/s10067-025-07606-6 · Cited by 2
Zerback, T., Koeder, C., Weder, S., Sputtek, A., Eckert, G. P., & Keller, M. (2025) · European Journal of Nutrition · doi:10.1007/s00394-025-03814-7 · Cited by 2
Kvestad, I., Ulak, M., McCann, A., Chandyo, R. K., Hysing, M., Schwinger, C., Ranjitkar, S., Ueland, P. M., Basnet, S., & Strand, T. A. (2025) · Journal of Nutrition · doi:10.1016/j.tjnut.2025.101305 · Cited by 2
Hanley‐Cook, G., Bastos-Moreira, Y., Martens, D. S., Dailey-Chwalibóg, T., Toe, L. C., de Kok, B., Ouédraogo, L. O., Argaw, A., Tesfamariam, K., Kolsteren, P. W., et al. (2024) · Food Science and Human Wellness · doi:10.26599/fshw.2024.9250304 · Cited by 3
Mickelson, B., Herfel, T. M., Booth, J. L., & Wilson, R. P. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814338-4.00009-x · Cited by 2
Armstrong, P., & Spence, A. A. (1991) · Baillière s Clinical Anaesthesiology · doi:10.1016/s0950-3501(05)80198-9 · Cited by 2
Genetic Contributions to Individual Differences in Memory Performance
Nilsson, L., Broeckhoven, C. V., & Adolfsson, R. (2001) · European Psychologist · doi:10.1027//1016-9040.6.4.264 · Cited by 2
Nutritional Complications and Emergencies
Szomstein, S., & Nguyen, D. (2016) · Springer eBooks · doi:10.1007/978-3-319-27114-9_22 · Cited by 2
Shane, B., & Stover, P. J. (2023) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2023.03.008 · Cited by 2
Functional profiling reveals a non-enzymatic role of NUDT5 in repressing purine de novo synthesisPreprint
Lin, J.-M. G., Nguyễn, A. T., Marques, A.-S. M. C., Scrofani, L., Daum, D., Bauer, L. G., Cheng, C., D’Angelo, L., Sánchez-Ávila, J., Bueschl, C., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.16.643506 · Cited by 2
Hemingway, D. C., & Howson, D. W. (2023) · InnovAiT Education and inspiration for general practice · doi:10.1177/17557380231179986 · Cited by 1
Fumonisin, Folate and Other Methyl Donors and Neural Tube Defects
Sant, K. E., Anderson, O. S., & Waes, J. B. G. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95488-4.00200-x · Cited by 1
Xie, X., Li, Z., Xiao, Q., Xiong, H. F., & Yuan, M. (2026) · Scientific Reports · doi:10.1038/s41598-026-38288-y · Cited by 1
Ayoub, G., & Brown, C. J. (2026) · Cells · doi:10.3390/cells15161453 · Cited by 1
Masking of vitamin B12 deficiency associated neuropathyby folic acid
van, A. J., Opperhuizen, A., & Ehjm, J. (2005) · Rivm (National Institute for Public Health and the Environment) · Cited by 1
Hematological Disorders Following Bariatric Surgery
Qiu, H., Green, R., & Chen, M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-804011-9.00046-7 · Cited by 1
Úbeda, N., Partearroyo, T., & Varela‐Moreiras, G. (2019) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831/a000537 · Cited by 1
Bioactive Agents as a Novel Therapy of Hyperhomocysteinemia
Khan, A. A., & Ashraf, M. (2021) · Springer eBooks · doi:10.1007/978-3-030-57839-8_19 · Cited by 1
Okeke, F. C., Capalino, D. F., Matarese, L. E., & Mullin, G. E. (2015) · Wiley eBooks · doi:10.1002/9781118512074.ch30 · Cited by 1
Blake, G. E. T., Zhao, X., Yung, H. W., Burton, G. J., Ferguson-Smith, A. C., Hamilton, R. S., & Watson, E. D. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.21.109256 · Cited by 2
Assessment of the B-Vitamin Status: Some Biochemical and Clinical Aspects
van den Berg, H. (1989) · Springer eBooks · doi:10.1007/978-1-4613-0753-2_55 · Cited by 1
Byrne, A. J. (2008) · Memorial University Research Repository (Memorial University)
Nelson, C. (2021) · Digital Commons - USU (Utah State University) · doi:10.26076/64f1-925f
Aguilera-Eguía, R. A., Castro-Arredondo, F. C., Campos-Carrión, P. F., & Ibacache-Palma, A. (2015) · Revista Española de Nutrición Humana y Dietética · doi:10.14306/renhyd.19.4.166
Iron Deficiency and Megaloblastic Anemias
Solomon, L. R. (1992) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-75865-2_6
Diseases of Nutrient De.ciencies
Golden, B. E. (2009) · CRC Press eBooks · doi:10.1201/9781420077544.ch10
Obitz, K. (2015) · Qucosa (Saxon State and University Library Dresden)
Jadavji, N. M. (2013) · eScholarship@McGill (McGill) · doi:10.82308/49571
Fumonisin, Folate and other Methyl Donors and Neural Tube Defects
Sant, K. E., Anderson, O. S., & van Waes, J. G. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.64292-7 · Cited by 1
Cognitive Decline and Dementia in Some Chronic Disorders
Nagaratnam, N., & Cheuk, G. (2018) · Springer eBooks · doi:10.1007/978-3-319-96998-5_28
The Role of the Mrj Co-chaperone During Early Mouse Embryonic Development
Watson, E. D. (2008) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/13949
Methionine synthase supports tumor tetrahydrofolate poolsPreprint
Wang, J. Z., Ghergurovich, J. M., Yang, L., & Rabinowitz, J. D. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.09.05.284521
Tajuddin, Q. M., Mukhopadhyay, M., & Bandyopadhyay, S. N. (2020) · INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH · doi:10.36106/ijsr/5809598
Bagley, P. J., & Shane, B. (2010) · CRC Press eBooks · doi:10.1201/b14669-38
McMartin, K. E. (2005) · Nutrition in exercise and sport · doi:10.1201/9781420037913.ch8
MAMMALIAN FOLYLPOLY-λ-GLUTAMATE SYNTHETASE
(2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1987.tb06084.x
Hahn, A., & Wolters, M. (2012) · Wiley eBooks · doi:10.1002/9783527653058.ch5
(EFSA), E. F. S. A. (2015) · EFSA Supporting Publications · doi:10.2903/sp.efsa.2015.en-845
Metadata
- Authors
- Shane, B., & Stokstad, E. L. R.
- ORCID
- Shane, Barry
- Venue
- Annual Review of Nutrition
- Publisher
- Annual Reviews
- Published
- 1985-07
- Volume
- 5
- Issue
- 1
- Pages
- 115-141
- ISSN
- 0199-9885 (ISSN-L)
- 1545-4312
- OpenAlex
- W2146178648
- Cited by
- 311
- References
- 38
- Citations by year
- 2026: 4 · 2025: 14 · 2024: 10 · 2023: 7 · 2022: 7 · 2021: 7 · 2020: 12 · 2019: 14 · 2018: 13 · 2017: 8 · 2016: 10 · 2015: 12 · 2014: 6 · 2013: 16 · 2012: 5
- FWCI
- 4.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01am008171-22)
- National Cancer Institute (CA-00697, CA 22717)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Folate and B Vitamins Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Porphyrin Metabolism and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Metabolism and Genetic Disorders
- Keywords
- vitamin B12, folic acid, vitamin B12 deficiency, methionine synthase, 5-methyltetrahydrofolate, folylpolyglutamate synthetase, folate retention, adenosylmethionine, methylenetetrahydrofolate reductase, folate metabolism, methyltransferase
- MeSH terms
- Amino Acids, Animals, Bone Marrow, Folic Acid, Folic Acid Deficiency, Formates, Formiminoglutamic Acid, Histidine, Homeostasis, Humans, Liver, Megaloblasts, Methionine, Methylation, Nitrous Oxide, Peptide Synthases, Pteroylpolyglutamic Acids, Purines, Serine, 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase, Thymidine Monophosphate, Thymidylate Synthase, Thyroid Gland, Vitamin B 12, Vitamin B 12 Deficiency
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