Prostanoid Receptors: Subtypes and Signaling

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

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Prostanoid Receptors: Structures, Properties, and Functions

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International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.

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G Protein-coupled Receptors

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G-protein-coupled receptor heterodimerization modulates receptor function

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The probable arrangement of the helices in G protein‐coupled receptors.

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Prostacyclin Synthase Expression Is Decreased in Lungs from Patients with Severe Pulmonary Hypertension

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Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

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Cloning and expression of cDNA for a human thromboxane A2 receptor

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Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3

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Gq-Dependent Signaling Upregulates COX2 in Glomerular Podocytes

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PGE2 inhibits spermatogonia differentiation in zebrafish: interaction with Fsh and an androgen

Crespo, D., Lemos, M. S., Zhang, Y., Safian, D., Norberg, B., Bogerd, J., & Schulz, R. W. (2019) · Journal of Endocrinology · doi:10.1530/joe-19-0309 · Cited by 25

Complex and Controversial Roles of Eicosanoids in Fungal Pathogenesis

Ruiz, S., Zamith‐Miranda, D., Takács, T., Gácser, A., Nosanchuk, J. D., & Guimaraes, A. J. (2021) · Journal of Fungi · doi:10.3390/jof7040254 · Cited by 25

Primate Granulosa Cell Response via Prostaglandin E2 Receptors Increases Late in the Periovulatory Interval1

Markosyan, N., Dozier, B. L., Lattanzio, F. A., & Duffy, D. M. (2006) · Biology of Reproduction · doi:10.1095/biolreprod.106.053769 · Cited by 25

Function of prostaglandin E2 EP receptors in the acute outcome of rodent hypoxic ischemic encephalopathy

Taniguchi, H., Anacker, C., Suarez-Mier, G. B., Wang, Q., & Andreasson, K. I. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.09.005 · Cited by 25

Molecular Pathways Linking Oxylipins to Nociception in Rats

Domenichiello, A. F., Sapio, M. R., Loydpierson, A. J., Maric, D., Goto, T., Horowitz, M. S., Keyes, G. S., Yuan, Z., Majchrzak‐Hong, S. F., Mannes, A. J., et al. (2020) · Journal of Pain · doi:10.1016/j.jpain.2020.09.001 · Cited by 24

Cyclic AMP‐mediated chloride secretion is induced by prostaglandin F2αin human isolated colon

Collins, D., Hogan, A. M., Mm, S., Baird, A. W., & Winter, D. C. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00464.x · Cited by 24

RhoGDI deficiency induces constitutive activation of Rho GTPases and COX-2 pathways in association with breast cancer progression

Bozza, W. P., Zhang, Y., Hallett, K., Rosado, L. A. R., & Zhang, B. (2015) · Oncotarget · doi:10.18632/oncotarget.5416 · Cited by 24

What you eat is what you are – A role for polyunsaturated fatty acids in neuroinflammation induced depression?

Pascoe, M. C., Crewther, S. G., Carey, L. M., & Crewther, D. P. (2011) · Clinical Nutrition · doi:10.1016/j.clnu.2011.03.013 · Cited by 24

MicroRNA and AU-rich element regulation of prostaglandin synthesis

Moore, A. E., Young, L. E., & Dixon, D. A. (2011) · Cancer and Metastasis Reviews · doi:10.1007/s10555-011-9300-5 · Cited by 24

Endogenous bioactive lipids and the regulation of conventional outflow facility

Wan, Z., Woodward, D. F., & Stamer, W. D. (2008) · Expert Review of Ophthalmology · doi:10.1586/17469899.3.4.457 · Cited by 24

Nerve Growth Factor Mediates a Switch in Intracellular Signaling for PGE2-Induced Sensitization of Sensory Neurons from Protein Kinase A to Epac

Vasko, M. R., Malty, R. H., Guo, C., Duarte, D. B., Zhang, Y. H., & Nicol, G. D. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104529 · Cited by 24

Prostaglandin E2 Stimulates the Production of Vascular Endothelial Growth Factor through the E-Prostanoid–2 Receptor in Cultured Human Lung Fibroblasts

Nakanishi, M., Sato, T., Li, Y., Nelson, A. J., Farid, M., Michalski, J., Kanaji, N., Wang, X., Basma, H., Patil, A., et al. (2011) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2010-0115oc · Cited by 24

Cyclooxygenase 2 Promotes Parathyroid Hyperplasia in ESRD

Zhang, Q., Qiu, J., Li, H., Lu, Y., Wang, X., Yang, J., Wang, S., Zhang, L., Gu, Y., Hao, C., et al. (2011) · Journal of the American Society of Nephrology · doi:10.1681/asn.2010060594 · Cited by 24

Role of EP2and EP4receptors in airway microvascular leak induced by prostaglandin E2

Jones, V. C., Birrell, M. A., Maher, S. A., Griffiths, M., Grace, M. S., O’Donnell, V. B., Clark, S., & Belvisi, M. G. (2015) · British Journal of Pharmacology · doi:10.1111/bph.13400 · Cited by 24

Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells.

Wise, H. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.02.018 · Cited by 26

Adenylyl Cyclase 6 Overexpression Decreases the Permeability of Endothelial Monolayers via Preferential Enhancement of Prostacyclin Receptor Function

Bundey, R. A., & Insel, P. A. (2006) · Molecular Pharmacology · doi:10.1124/mol.106.028035 · Cited by 24

Identification by site-directed mutagenesis of amino acids contributing to ligand-binding specificity or signal transduction properties of the human FP prostanoid receptor

Neuschäfer‐Rube, F., Engemaier, E., Koch, S., Böer, U., & Püschel, G. P. (2003) · Biochemical Journal · doi:10.1042/bj20021429 · Cited by 24

Regulation of Calcium Channels and Exocytosis in Mouse Adrenal Chromaffin Cells by Prostaglandin EP3 Receptors

Jewell, M. L., BREYER, R. M., & Currie, K. (2011) · Molecular Pharmacology · doi:10.1124/mol.110.068569 · Cited by 24

A prostaglandin E2 receptor subtype EP1-selective antagonist, ONO-8711, suppresses 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis

Makita, H., Mutoh, M., Maruyama, T., Yonemoto, K., Kobayashi, A., Fujitsuka, H., Toida, M., Shibata, T., Miyamoto, S., Yasui, Y., et al. (2006) · Carcinogenesis · doi:10.1093/carcin/bgl178 · Cited by 24

Prostaglandin EP1 Receptor Down-regulates Expression of Cyclooxygenase-2 by Facilitating Its Proteasomal Degradation

Haddad, A., Flint-Ashtamker, G., Minzel, W., Sood, R., Rimon, G., & Barki‐Harrington, L. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.304220 · Cited by 23

The distribution of the prostaglandin E receptor type 2 (EP2) in the detrusor of the guinea pig

Rahnama’i, M. S., Biallosterski, B. T., Wachter, S. D., Kerrebroeck, P. V., & van Koeveringe, G. A. (2012) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2012.08.005 · Cited by 23

The prostaglandin E2 receptor, EP2, regulates survivin expression via an EGFR/STAT3 pathway in UVB‐exposed mouse skin

Chun, K., & Langenbach, R. J. (2011) · Molecular Carcinogenesis · doi:10.1002/mc.20728 · Cited by 23

Platelet Shape Change

Aslan, J. E. (2017) · Springer eBooks · doi:10.1007/978-3-319-47462-5_24 · Cited by 23

Risk management profile of etoricoxib: an example of personalized medicine

Patrignani, P. (2008) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s3209 · Cited by 23

Intravenously Administered Vasodilatory Prostaglandins Increase Retinal and Choroidal Blood Flow in Rats

Mori, A., Saito, M., Sakamoto, K., Nakahara, T., & Ishii, K. (2007) · Journal of Pharmacological Sciences · doi:10.1254/jphs.fp0061061 · Cited by 23

Prostaglandin D2 Induces IL-8 and GM-CSF by Bronchial Epithelial Cells in a CRTH2-Independent Pathway

Chiba, T., Kanda, A., Ueki, S., Ito, W., Kamada, Y., Oyamada, H., Saito, N., Kayaba, H., & Chihara, J. (2006) · International Archives of Allergy and Immunology · doi:10.1159/000095436 · Cited by 23

Prevention of rat cortical neurons from prostaglandin E2-induced apoptosis by glycogen synthase kinase-3 inhibitors

Takadera, T., & Ohyashiki, T. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.02.014 · Cited by 23

Peroxisome Proliferator-Activated Receptor-γ Suppresses Cyclooxygenase-2 Expression in Human Prostate Cells

Sabichi, A. L., Subbarayan, V., Llansa, N., Lippman, S. M., & Menter, D. G. (2004) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.1704.13.11 · Cited by 23

Translational profiling of mouse dopaminoceptive neurons reveals region-specific gene expression, exon usage, and striatal prostaglandin E2 modulatory effects

Montalban, E., Giralt, A., Taing, L., Schut, E. H. S., Supiot, L. F., Castell, L., Nakamura, Y., de Pins, B., Pelosi, A., Goutebroze, L., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01439-4 · Cited by 24

Neural Controls of Prostaglandin 2 Pyrogenic, Tachycardic, and Anorexic Actions Are Anatomically Distributed

Skibicka, K. P., Alhadeff, A. L., Leichner, T. M., & Grill, H. J. (2011) · Endocrinology · doi:10.1210/en.2010-1309 · Cited by 22

Matrix Metalloproteinase-Dependent Microsomal Prostaglandin E Synthase-1 Expression in Macrophages: Role of TNF-α and the EP4 Prostanoid Receptor

Khan, K. M. F., Kothari, P., Du, B., Dannenberg, A. J., & Falcone, D. J. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1102383 · Cited by 22

Identification of Drugs that Regulate Dermal Stem Cells and Enhance Skin Repair

Naska, S., Yuzwa, S. A., Johnston, A. P. W., Paul, S., Smith, K. M., Paris, M., Sefton, M. V., Datti, A., Miller, F. D., & Kaplan, D. R. (2015) · Stem Cell Reports · doi:10.1016/j.stemcr.2015.12.002 · Cited by 22

The prostaglandin transporter (PGT) as a potential mediator of ovulation

Yerushalmi, G., Markman, S., Yung, Y., Maman, E., Aviel‐Ronen, S., Orvieto, R., Adashi, E. Y., & Hourvitz, A. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aad2709 · Cited by 22

Prostaglandin E2 stimulates urokinase‐type plasminogen activator receptor via EP2 receptor‐dependent signaling pathways in human AGS gastric cancer cells

Lian, S., Xia, Y., Ung, T. T., Khoi, P. N., Yoon, H. J., Lee, S. G., Kim, K. K., & Jung, Y. D. (2016) · Molecular Carcinogenesis · doi:10.1002/mc.22524 · Cited by 22

Lipopolysaccharide induces proinflammatory cytokines and chemokines in experimental otitis media through the prostaglandin D2 receptor (DP)-dependent pathway

Eguchi, M., Kariya, S., Okano, M., Higaki, T., Makihara, S., Fujiwara, T., Nagata, K., Hirai, H., Narumiya, S., Nakamura, M., et al. (2010) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2010.04292.x · Cited by 22

PGF2α-associated vascular smooth muscle hypertrophy is ROS dependent and involves the activation of mTOR, p70S6k, and PTEN

Rice, K. M., Uddemarri, S., Desai, D. H., Morrison, R. G., Harris, R. T., Wright, G. L., & Blough, E. R. (2007) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2007.10.009 · Cited by 24

EP2 receptor stimulation promotes calcium responses in astrocytes via activation of the adenylyl cyclase pathway

Cesare, A. D., Piccolo, P. D., Zacchetti, D., & Grohovaz, F. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-006-6262-9 · Cited by 22

Bystanders or not? Microglia and lymphocytes in aging and stroke

Chauhan, A., & Nguyen, J. (2022) · Neural Regeneration Research · doi:10.4103/1673-5374.360345 · Cited by 21

Differential expression of E‐prostanoid receptors in human hepatocellular carcinoma

Breinig, M., Rieker, R. J., Eiteneuer, E. M., Wertenbruch, T., Haugg, A. M., Helmke, B. M., Schirmacher, P., & Kern, M. A. (2007) · International Journal of Cancer · doi:10.1002/ijc.23098 · Cited by 21

Inhibition of Phosphodiesterase Type 3 Dilates the Rat Ductus Arteriosus Without Inducing Intimal Thickening

Ichikawa, Y., Yokoyama, U., Iwamoto, M., Oshikawa, J., Okumura, S., Sato, M., Yokota, S., Masuda, M., Asou, T., & Ishikawa, Y. (2012) · Circulation Journal · doi:10.1253/circj.cj-12-0215 · Cited by 21

Generation of ROS by CAY10598 leads to inactivation of STAT3 signaling and induction of apoptosis in human colon cancer HCT116 cells

Chae, I. G., Kim, D.-H., Kundu, J. K., Jeong, C., Kundu, J. K., & Chun, K. (2014) · Free Radical Research · doi:10.3109/10715762.2014.951838 · Cited by 21

Regulatory roles of PGE2 in LPS-induced tissue damage in bovine endometrial explants

Deng, Y., Liu, B., Mao, W., Shen, Y., Fu, C., Gao, L., Zhang, S., Wu, J., Li, Q., Li, T., et al. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.03.044 · Cited by 22

G-Protein-Coupled Receptors and Ischemic Stroke: a Focus on Molecular Function and Therapeutic Potential

Vahidinia, Z., Joghataei, M. T., Beyer, C., Karimian, M., & Tameh, A. A. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02435-5 · Cited by 22

Myeloid-Derived Suppressor Cells Dampen Airway Inflammation Through Prostaglandin E2 Receptor 4

van Geffen, C., Deißler, A., Beer‐Hammer, S., Nürnberg, B., Handgretinger, R., Renz, H. E., Hartl, D., & Kolahian, S. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.695933 · Cited by 21

Prostaglandin E2 Represses Interleukin 1 Beta-Induced Inflammatory Mediator Output from Pregnant Human Myometrial Cells Through the EP2 and EP4 Receptors1

Mosher, A. A., Rainey, K. J., Giembycz, M. A., Wood, S. L., & Slater, D. M. (2012) · Biology of Reproduction · doi:10.1095/biolreprod.112.100099 · Cited by 21

Mechanisms underlying the relaxation response induced by bradykinin in the epithelium‐intact guinea‐pig trachea in vitro

Schlemper, V., Medeiros, R., Ferreira, J., Campos, M. M., & Calixto, J. Β. (2005) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706222 · Cited by 21

Interactions between prostaglandins, leukotrienes and HIV-1: Possible implications for the central nervous system

Bertin, J. O., Barat, C., Méthot, S., & Tremblay, M. J. (2012) · Retrovirology · doi:10.1186/1742-4690-9-4 · Cited by 21

Expression of Prostaglandin PGE 2 Receptors under Conditions of Aging and Stress and the Protective Effect of the EP2 Agonist Butaprost on Retinal Ischemia

Osborne, N. N., Li, G., Ji, D., da Costa, B. L. A., Fawcett, R. J., Kang, K. D., & Rittenhouse, K. D. (2009) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.08-3185 · Cited by 21

E-Ring 8-Isoprostanes Are Agonists at EP2- and EP4-Prostanoid Receptors on Human Airway Smooth Muscle Cells and Regulate the Release of Colony-Stimulating Factors by Activating cAMP-Dependent Protein Kinase

Clarke, D. L., Belvisi, M. G., Hardaker, E. L., Newton, R. C., & Giembycz, M. A. (2004) · Molecular Pharmacology · doi:10.1124/mol.104.006486 · Cited by 21

A Prostacyclin Receptor Antagonist Inhibits the Sensitized Release of Substance P from Rat Sensory Neurons

Nakae, K., Saito, K., Iino, T., Yamamoto, N., Wakabayashi, M., Yoshikawa, S., Matsushima, S., Miyashita, H., Sugimoto, H., Kiba, A., et al. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.091967 · Cited by 21

Comparison of Pharmacokinetics and Vasodilatory Effect of Nebulized and Infused Iloprost in Experimental Pulmonary Hypertension: Rapid Tolerance Development

SCHERMULY, R. T., Schulz, A., Ghofrani, H. A., Breitenbach, S. C., Weißmann, N., Hildebrand, M. S., Kurz, J., Grimminger, F., & Seeger, W. (2006) · Journal of Aerosol Medicine · doi:10.1089/jam.2006.19.353 · Cited by 21

Discovery of novel biaryl heterocyclic EP1 receptor antagonists

Hall, A., Bit, R. A., Brown, S. H., Chaignot, H. M., Chessell, I. P., Coleman, T., Giblin, G. M. P., Hurst, D. N., Kilford, I. R., Lewell, X. Q., et al. (2006) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2006.02.014 · Cited by 21

SC-19220, Antagonist of Prostaglandin E2 Receptor EP1, Inhibits Osteoclastogenesis by RANKL

Tsujisawa, T., Inoue, H., & Nishihara, T. (2005) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.041011 · Cited by 23

Discovery of novel aminothiadiazole amides as selective EP3 receptor antagonists

Hilfiker, M. A., Wang, N., Hou, X., Du, Z., Pullen, M. A., Nord, M., Nagilla, R., Fries, H. E., Wu, C. W., Sulpizio, A. C., et al. (2009) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2009.05.074 · Cited by 20

The Cell Biology of Vasopressin Action

Brown, D., & Fenton, R. A. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4160-6193-9.10011-9 · Cited by 20

Role of the COX2-PGE2 axis in S. pneumoniae-induced exacerbation of experimental fibrosis

Bormann, T., Maus, R., Stolper, J., Jonigk, D. D., Welte, T., Gauldie, J., Kolb, M. R. J., & Maus, U. A. (2020) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00024.2020 · Cited by 20

Characterization of airborne PAHs and metals associated with PM10 fractions collected from an urban area of Sri Lanka and the impact on airway epithelial cells.

Abayalath, N., Malshani, I., Ariyaratne, R., Zhao, S., Zhong, G., Zhang, G., Manipura, A., SIRIBADDANA, A. A., Karunaratne, P., & Kodithuwakku, S. P. (2021) · Chemosphere · doi:10.1016/j.chemosphere.2021.131741 · Cited by 20

Lipid Signalling in the Pathology of Autism Spectrum Disorders

Wong, C. T., & Crawford, D. A. (2013) · Springer eBooks · doi:10.1007/978-1-4614-4788-7_68 · Cited by 24

Sex hormone effects in non-pregnant rat and human myometrium

Vedernikov, Y. P., Hartke, J. R., de Long, M. A., Saade, G. R., & Garfield, R. E. (2003) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/s0301-2115(02)00415-3 · Cited by 20

Identification and optimization of novel 1,3,4-oxadiazole EP1 receptor antagonists

Hall, A., Brown, S. H., Chowdhury, A., Giblin, G. M. P., Gibson, M., Healy, M. P., Livermore, D. G., Wilson, R. J. M., Naylor, A., Rawlings, D. A., et al. (2007) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2007.06.014 · Cited by 20

Phosphatidylinositol transfer protein α regulates growth and apoptosis of NIH3T3 cells

Schenning, M., van Tiel, C. M., van Manen, D., Stam, J. C., Gadella, B. M., WIRTZ, K. W. A., & Snoek, G. T. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m400127-jlr200 · Cited by 20

Structures of human prostaglandin F2α receptor reveal the mechanism of ligand and G protein selectivity

Lv, X., Gao, K., Nie, J., Zhang, X., Zhang, S., Ren, Y., Sun, X., Li, Q., Huang, J., Liu, L., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-43922-8 · Cited by 19

EP2 receptor mediated cAMP release is augmented by PGF2α activation of the FP receptor via the calcium-calmodulin pathway

Abera, A. B., Sales, K. J., Catalano, R. D., Katz, A. A., & Jabbour, H. N. (2009) · Cellular Signalling · doi:10.1016/j.cellsig.2009.09.012 · Cited by 19

Characterization of the effects of vasoactive substances on the bulbus arteriosus of the eel, Anguilla rostrata

Evans, D. H., Harrie, A. C., & Kozlowski, M. S. (2003) · Journal of Experimental Zoology Part A Comparative Experimental Biology · doi:10.1002/jez.a.10238 · Cited by 19

Dissociation between the translocation and the activation of Akt in fMLP-stimulated human neutrophils—effect of prostaglandin E2

Burelout, C., Naccache, P. H., & Bourgoin, S. G. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0406256 · Cited by 19

Analgesic and anti‐inflammatory properties of novel, selective, and potent EP4 receptor antagonists

Chandrasekhar, S., Yu, X., Harvey, A. K., Oskins, J. L., Lin, C., Wang, X.-S., Blanco, M.-J., Fisher, M. J., Kuklish, S. L., Schiffler, M. A., et al. (2017) · Pharmacology Research & Perspectives · doi:10.1002/prp2.316 · Cited by 19

Genetic and molecular biology of bladder cancer among Iranian patients

Mojarrad, M., & Moghbeli, M. (2020) · Molecular Genetics & Genomic Medicine · doi:10.1002/mgg3.1233 · Cited by 19

A short guide to the nomenclature of seven-transmembrane spanning receptors for lipid mediators

Howlett, A. C. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.05.003 · Cited by 19

Bone Biomechanical Properties in EP4 Knockout Mice

Akhter, M. P., Cullen, D. M., & Pan, L. C. (2006) · Calcified Tissue International · doi:10.1007/s00223-005-0186-5 · Cited by 19

Parathyroid Hormone Induces E4bp4 Messenger Ribonucleic Acid Expression Primarily through Cyclic Adenosine 3′,5′-Monophosphate Signaling in Osteoblasts

Ozkurt, I. C., Pirih, F. Q. M., & Tetradis, S. (2004) · Endocrinology · doi:10.1210/en.2003-1436 · Cited by 19

Inhibition of prostaglandin synthesis and actions contributes to the beneficial effects of calcitriol in prostate cancer

Krishnan, A. V., Srinivas, S., & Feldman, D. (2009) · Dermato-Endocrinology · doi:10.4161/derm.1.1.7106 · Cited by 19

Possible cross‐regulation of the E prostanoid receptors

Tober, K. L., Thomas‐Ahner, J. M., Maruyama, T., & Oberyszyn, T. M. (2007) · Molecular Carcinogenesis · doi:10.1002/mc.20347 · Cited by 19

Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength

Zhang, M., Feigenson, M., Sheu, T., Awad, H. A., Schwarz, E. M., Jonason, J. H., Loiselle, A. E., & O’Keefe, R. J. (2014) · Bone · doi:10.1016/j.bone.2014.11.018 · Cited by 19

Rebamipide retards CCl4-induced hepatic fibrosis in rats: Possible role for PGE2

Zakaria, S., & El‐Sisi, A. E. (2016) · Journal of Immunotoxicology · doi:10.3109/1547691x.2015.1128022 · Cited by 19

Prostaglandin E2 EP4 Receptor Activation Attenuates Neuroinflammation and Early Brain Injury Induced by Subarachnoid Hemorrhage in Rats

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Molecular cloning and characterization of chicken prostaglandin E receptor subtypes 2 and 4 (EP2 and EP4)

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