The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Sodium-Calcium Exchange: A Molecular Perspective
Abstract
▪ Abstract Plasma membrane Na+-Ca 2+ exchange is an essential component of Ca 2+ signaling pathways in several tissues. Activity is especially high in the heart where the exchanger is an important regulator of contractility. An expanding exchanger superfamily includes three mammalian Na+-Ca 2+ exchanger genes and a number of alternative splicing products. New information indicates that the exchanger protein has nine transmembrane segments. The exchanger, which transports Na+ and Ca 2+, is also regulated by these substrates. Some molecular information is available on regulation by Na+ and Ca 2+ and by PIP 2 and phosphorylation. Altered expression of the exchanger in pathophysiological states may contribute to various cardiac phenotypes. Use of transgenic approaches is beginning to improve our knowledge of exchanger function.
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Cited by
Calcium Cycling and Signaling in Cardiac Myocytes
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SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans
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Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death
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Calcium Absorption Across Epithelia
Hoenderop, J. G. J., Nilius, B., & Bindels, R. J. M. (2005) · Physiological Reviews · doi:10.1152/physrev.00003.2004 · Cited by 936
Metadata
- Authors
- Philipson, K. D., & Nicoll, D. A.
- Venue
- Annual Review of Physiology
- Publisher
- Annual Reviews
- Published
- 2000-03
- Volume
- 62
- Issue
- 1
- Pages
- 111-133
- ISSN
- 0066-4278 (ISSN-L)
- 1545-1585
- OpenAlex
- W2125155338
- Cited by
- 548
- References
- 55
- FWCI
- 3.37
- Type
- journal article
- Language
- en
- Open access
- closed
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