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Adenomyosis and leiomyoma: differential diagnosis with MR imaging.
Abstract
To assess the capability of magnetic resonance (MR) imaging to enable differentiation of adenomyosis from leiomyoma, a prospective study was performed in 21 premenopausal patients with a strong clinical suggestion of adenomyosis. Histologic findings from hysterectomy (19 patients) and biopsy specimens (two patients) showed that eight patients had adenomyosis (three focal, five diffuse) and 12 had leiomyomas (five of the 12 also had microscopic foci of adenomyosis); one patient had a normal uterus. All eight cases of adenomyosis were correctly diagnosed from MR images. On T2-weighted MR images, diffuse adenomyosis appeared as a thickening of the junctional zone, whereas focal adenomyosis appeared as a low-signal-intensity mass poorly marginated from the adjacent myometrium. Ten of the 12 leiomyomas were correctly diagnosed from MR images. In the other two cases of leiomyoma, differentiation between focal adenomyosis and leiomyoma was not possible. Microscopic foci of adenomyosis were not demonstrated with MR imaging.
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Citations
Cited by
Pathophysiology of adenomyosis
Ferenczy, A. (1998) · Human Reproduction Update · doi:10.1093/humupd/4.4.312 · Cited by 508
The FIGO classification of causes of abnormal uterine bleeding in the reproductive years
Munro, M. G., Critchley, H. O. D., & Fraser, I. S. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.03.079 · Cited by 409
Uterine Adenomyosis: Endovaginal US and MR Imaging Features with Histopathologic Correlation
Reinhold, C., Tafazoli, F., Mehio, A., Wang, L., Atri, M., Siegelman, E. S., & Rohoman, L. (1999) · RadioGraphics · doi:10.1148/radiographics.19.suppl_1.g99oc13s147 · Cited by 297
Magnetic resonance imaging and transvaginal ultrasonography for the diagnosis of adenomyosis
Dueholm, M., Lundorf, E., Hansen, E. S., Sørensen, J. S., Ledertoug, S., & Olesen, F. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(01)01962-8 · Cited by 273
Prevalence and risk factors of adenomyosis at hysterectomy
Bergholt, T., Eriksen, L., Berendt, N., Jacobsen, M., & Hertz, J. B. (2001) · Human Reproduction · doi:10.1093/humrep/16.11.2418 · Cited by 227
Metadata
- Authors
- Mark, A. S., Hricak, H., Heinrichs, L. W., Hendrickson, M. R., Winkler, M. L., Bachica, J. A., & Stickler, J. E.
- Venue
- Radiology
- Published
- 1987-05
- Volume
- 163
- Issue
- 2
- Pages
- 527-529
- ISSN
- 0033-8419 (ISSN-L)
- 1527-1315
- OpenAlex
- W2165290782
- Cited by
- 187
- References
- 0
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- closed
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- Mark, A. S., Hricak, H., Heinrichs, L. W., Hendrickson, M. R., Winkler, M. L., Bachica, J. A., & Stickler, J. E. (1987). Adenomyosis and leiomyoma: differential diagnosis with MR imaging. Radiology. https://doi.org/10.1148/radiology.163.2.3562836
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