ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakage

Hafezi-Moghadam, Ali, Thomas, Kennard L., Wagner, Denisa D.·2007·American Journal of Physiology-Cell Physiology

Cited by (149)

Items 101–149 of 149

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  5. Magnetic resonance imaging biomarkers of exercise‐induced improvement of oxidative stress and inflammation in the brain of old high‐fat‐fed ApoE−/− mice
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  6. Transcriptional regulation of APP by apoE: To boldly go where no isoform has gone before
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  7. In utero exposure to maternal anti–aquaporin-4 antibodies alters brain vasculature and neural dynamics in male mouse offspring
    Simone Mader, Lior Brimberg, An Vo, Joshua J. Strohl, James M. Crawford, Alexandre Bonnin, Joseph Carrión, Delcora Campbell, Tomas S. Huerta, Andrea La Bella et al. · 2022 · Science Translational Medicine
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    Kristen D. Onos, Peter Bor‐Chian Lin, Ravi S. Pandey, Scott A. Persohn, Charles P. Burton, Ethan W. Miner, Kierra Eldridge, Jonathan Nyandu Kanyinda, Kate E. Foley, Gregory W. Carter et al. · 2024 · Alzheimer s & Dementia
  9. Aging disrupts blood–brain and blood-spinal cord barrier homeostasis, but does not increase paracellular permeability
    Mitchell J Cummins, Ethan T Cresswell, Renee J Bevege, Doug William Smith · 2024 · GeroScience
  10. Exercise Does Not Protect against Peripheral and Central Effects of a High Cholesterol Diet Given Ad libitum in Old ApoE−/− Mice
    Di Cataldo, Vanessa, Géloën, Alain, Langlois, Jean-Baptiste, Chauveau, Fabien, Thézé, Benoît, Hubert, Violaine, Wiart, Marlène, Chirico, Erica N., Rieusset, Jennifer, Vidal, Hubert et al. · 2016 · Frontiers in Physiology
  11. Platelet adhesion receptors do not modulate infarct volume after a photochemically induced stroke in mice
    Kim Frederix, Anil Kumar Chauhan, Janka Kisucka, Bing–Qiao Zhao, Erik I. Hoff, Henri M.H. Spronk, Hugo Ten Cate, Denisa D. Wagner · 2007 · Brain Research
  12. Interarm differences in systolic blood pressure and the risk of dementia and subclinical brain injury
    Matthew Paul Pase, Alexa Beiser, Hugo Javier Aparicio, Charles S DeCarli, Ramachandran Srini Vasan, Joanne M. Murabito, Sudha S. Seshadri · 2015 · Alzheimer s & Dementia
  13. Link among apolipoprotein E E4, gait, and cognition in neurodegenerative diseases: ONDRI study
    Ryota Sakurai, Frederico Pieruccini‐Faria, Benjamin F. Cornish, Julia Fraser, Malcolm A. Binns, Derek Beaton, Allison Ann Dilliott, Donna T. Kwan, Joel Ramirez, Brian Tan et al. · 2024 · Alzheimer s & Dementia
  14. An iTRAQ approach to quantitative proteome analysis of cerebrospinal fluid from patients with tuberculous meningitis
    Ou · 2013 · BioScience Trends
  15. A Novel Nonradioactive Method to Evaluate Vascular Barrier Breakdown and Leakage
    George Trichonas, Akrivi Manola, Yuki Morizane, Aristomenis Thanos, Xanthi Koufomichali, Thanos D. Papakostas, Sandra Rocio Montezuma, LUCY H. Y. YOUNG, Joan W. Miller, Evangelos S. Gragoudas et al. · 2010 · Investigative Ophthalmology & Visual Science
  16. Regional Differences in Penetration of the Protein Stabilizer Trimethoprim (TMP) in the Rat Central Nervous System
    Benjamin Victor Ineichen, Serena Di Palma, Endre Laczkó, Shane Antony Liddelow, Susanne Neumann, Martin E. Schwab, Alice C. Mosberger · 2020 · Frontiers in Molecular Neuroscience
  17. Can Control Infections Slow Down the Progression of Alzheimer’s Disease? Talking About the Role of Infections in Alzheimer’s Disease
    Mingchao Shi, Chunrong Li, Xiaoping Tian, Fengna Chu, Jie Zhu · 2021 · Frontiers in Aging Neuroscience
  18. Depressive symptoms in chronic hepatitis C are associated with plasma apolipoprotein E deficiency
    David A. Sheridan, Simon H. Bridge, Mary M.E. Crossey, Daniel Jeffery Felmlee, Howard C. Thomas, R. Dermot G. Neely, Simon David Taylor-Robinson, Margaret F. Bassendine · 2014 · Metabolic Brain Disease
  19. Lumbar spinal cord microglia exhibited increased activation in aging dogs compared with young adult dogs
    Christine M. Toedebusch, Virginia B. Garcia, John C. Snyder, Maria R. Jones, David J. Schulz, Gayle C. Johnson, Eric Villalón, Joan R. Coates, Michael L. Garcia · 2019 · GeroScience
  20. The Spatiotemporal Coupling: Regional Energy Failure and Aberrant Proteins in Neurodegenerative Diseases
    Assunta Virtuoso, Anna Maria Colangelo, Nicola Maggio, Uriel Fennig, Nitai Weinberg, Michèle Papa, Ciro De Luca · 2021 · International Journal of Molecular Sciences
  21. Oral diseases as emerging risk factors for Alzheimer’s disease: A scoping review
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  22. Brain vascular biology
    Yao Yao, Sonali S. Shaligram, Hua Su · 2020 · Handbook of clinical neurology
  23. Characterization of spontaneous hydrocephalus development in the young atherosclerosis-prone mice
    Chuanguo Liu, Guorong Li, Pingping Wang, Yan Wang, Jie Pan · 2017 · Neuroreport
  24. The blood-brain barrier models to study apolipoprotein E genotypes in Alzheimer’s disease
    Irundika H.K. Dias, Rachelle Taiwo, Dan Ma · 2021 · Neural Regeneration Research
  25. APOΕ gene polymorphism and markers of brain damage in the outcomes of severe traumatic brain injury in children
    Elena G. Sorokina, Ж. Б. Семенова, N.S. Averianova, Olga V. Karaseva, E N Arsenieva, V. I. Lukyanov, Valentin Palladievich Reutov, A. Yu. Asanov, L. M. Roshal, Vsevolod G. Pinelis · 2020 · S S Korsakov Journal of Neurology and Psychiatry
  26. Biochemical‐ and Biophysical‐Induced Barriergenesis in the Blood–Brain Barrier: A Review of Barriergenic Factors for Use in In Vitro Models
    Christina L. Schofield, Aleixandre Rodrigo‐Navarro, Matthew John Dalby, Tom Van Agtmael, Manuel Salmerón‐Sánchez · 2021 · Advanced NanoBiomed Research
  27. Silica Nanoparticle Exposure Implicates β-Amyloid (1–42) Inbound and the Accelerating Alzheimer’s Disease Progression in Mice Overexpressing Mutated Forms of Human Amyloid Precursor Protein and Presenilin 1 Genes
    Wei Wei, Hang Sun, Bingwei V. Yang, Chengyu Zhu, Erqun Song, Yang Song · 2024 · Chemical Research in Toxicology
  28. Neutral Lipid Determination in Peripheral Blood Mononuclear Cells: A Useful Tool for Diagnostic and Therapeutic Interventions in Dementia
    Laura Anchisi · 2012 · Journal of Molecular Biomarkers & Diagnosis
  29. Apolipoprotein E Plasma Concentrations Are Predictive of Recurrent Strokes: Insights From the SPARCL Trial
    Kévin Chemello, Alexis F. Guédon, Romuald Techer, Ali K. Jaafar, Sam Guilhen, Michael J. Swietek, Gilles C. Lambert, Antonio Gallo · 2025 · Journal of the American Heart Association
  30. Central nervous system effects of ambient particulate matter: the role of oxidative stress and inflammation
    Michael T. Kleinman · 2014
  31. Apolipoprotein E deficiency exacerbates blood-brain barrier disruption and hyperglycemia-associated hemorrhagic transformation after ischemic stroke
    Changlong Leng, Kuan‐Chia Lin, Mei Zhou, Tao Xiaoqin, Binlian Sun, Xiji Shu, Wei Liu · 2024 · Journal of Stroke and Cerebrovascular Diseases
  32. High-density lipoproteins at the interface between central nervous system and plasma lipoprotein metabolism
    Jérôme Robert, Wai Hang Cheng, Arooj Hayat, Taylor Ward-Able, Cheryl Lea Wellington · 2015 · Clinical Lipidology
  33. CNS Barriers in Neurotrauma
    Adam Chodobski, Brian J. Zink, Joanna Szmydynger‐Chodobska · 2013 · Springer eBooks
  34. Polymorphism of the APOE Gene and Markers of Brain Damage in the Outcomes of Severe Traumatic Brain Injury in Children
    Elena G. Sorokina, Ж. Б. Семенова, N. S. Averianova, Olga V. Karaseva, E N Arsenieva, V. I. Lukyanov, Valentin Palladievich Reutov, A. Yu. Asanov, L. M. Roshal, Vsevolod G. Pinelis · 2020 · Neuroscience and Behavioral Physiology
  35. Targeted inCITE-Seq Analysis Identifies the Loss of Nuclear TDP-43 in Endothelium as a Mediator of Blood Brain Barrier Signaling Pathway Dysfunction in Neurodegeneration
    Omar M. Omar, Amy L. Kimble, Cheemala Ashok, Jordan D. Tyburski, Swati Pandey, Qian Wu, Bo Reese, Evan R. Jellison, Yunfeng Li, Bing Hao et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  36. Pathophysiology of Vascular Cognitive Impairment (II): Amyloid Contribution in Vascular Cognitive Impairment
    Ho Ko, Bonnie Y. K. Lam, Vincent Mok · 2020 · Stroke revisited
  37. Mechanisms of Blood–Retinal Barrier Breakdown in Diabetic Retinopathy
    Ali Hafezi‐Moghadam · 2011 · Springer eBooks
  38. Linking periodontitis and Alzheimer’s disease: systemic inflammation as a shared mechanism
    Claudio Cesari, Giada Belleri, Simone Fabrizi, Francesca Zangari · 2025 · Academia molecular biology and genomics.
  39. The Role of Apolipoprotein E Concentration and Isoform in Amyloid-beta Metabolism In Vivo
    Joseph M. Castellano · 2011 · Open Scholarship Institutional Repository (Washington University in St. Louis)
  40. Implications of cholesterol and cholesterol-lowering therapy in Alzheimer s disease
    Daniel Famer · 2007 · Figshare
  41. Characterization of blood-brain barrier disruption in a focal model of neuromyelitis optica
    Winkler, Anne · 2015
  42. Granzyme B in skin aging, injury and repair
    Paul Hiebert · 2013 · cIRcle (University of British Columbia)
  43. The role of transglutaminases in the development of abdominal aortic aneurysms
    Kathryn Jane Griffin · 2016 · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
  44. Cardiovascular and Retinal Vascular Changes in Preclinical Alzheimer's Disease
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  45. Inside the Oral Microbiome: How Periodontitis May Increase the Risk for Alzheimers Disease
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  46. Effects of aging and long-term dietary restrictions on cholesterol metabolism in the rat forebrain
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  47. APOE4-APP interactions exert early influences on cerebrovascular structure and function: implications for Alzheimer’s disease
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  48. Is there a role for apolipoprotein E in perinatal brain injury?
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