The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.
Abstract
Physiological and pharmacological studies of hormones, drugs, and neurotransmitters often generate families of sigmoidal dose-response curves. Optimally efficient data analysis should involve simultaneous description of all curves, rather than fitting each one individually. We have developed a general computerized method to describe the dose-response curves in terms of basal and maximal responses, ED50, and curve shape or steepness. This facile method permits rigorous statistical analysis, provides a basis for pooling of information from separate experiments, and allows one to test which characteristics are shared by various curves.
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Citations
Cites
Rodbard, D. (1974) · Clinical Chemistry · doi:10.1093/clinchem/20.10.1255 · Cited by 1,040
Self-citationApplication of the Logistic Function to Bio-Assay
Berkson, J. (1944) · Journal of the American Statistical Association · doi:10.1080/01621459.1944.10500699 · Cited by 851
A Generalization of the Probit and Logit Methods for Dose Response Curves
Prentice, R. L. (1976) · Biometrics · doi:10.2307/2529262 · Cited by 405
Caron, M. G., Beaulieu, M., Raymond, V., Gagné, B., Drouin, J., Lefkowitz, R. J., & Labrie, F. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38065-1 · Cited by 383
Role of carbohydrate of human chorionic gonadotropin in the mechanism of hormone action
Moyle, W. R., Bahl, O. P., & März, L. (1975) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)40704-7 · Cited by 249
Statistical characterization of the random errors in the radioimmunoassay dose--response variable.
Rodbard, D., Lenox, R. H., Wray, H. L., & Ramseth, D. (1976) · Clinical Chemistry · doi:10.1093/clinchem/22.3.350 · Cited by 234
Self-citationUse of a specific probe for ovalbumin messenger RNA to quantitate estrogen-induced gene transcripts
Harris, S. E., Rosen, J. M., Means, A. R., & O'Malley, B. W. (1975) · Biochemistry · doi:10.1021/bi00681a006 · Cited by 214
Brown, E. M., Fedak, S. A., Woodard, C., & Aurbach, G. D. (1976) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)33731-6 · Cited by 124
Drouin, J., Léan, A. D., RAINVILLE, D., Lachance, R., & Labrie, F. (1976) · Endocrinology · doi:10.1210/endo-98-2-514 · Cited by 117
Rodbard, D. (1974) · Endocrinology · doi:10.1210/endo-94-5-1427 · Cited by 116
Self-citation
Cited by
Roth, B. L. (2016) · Neuron · doi:10.1016/j.neuron.2016.01.040 · Cited by 1,742
Laakso, M., Edelman, S. V., Brechtel, G., & Baron, A. D. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114644 · Cited by 930
Wang, J.-W., David, D. J., Monckton, J. E., Battaglia, F., & Hen, R. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.3632-07.2008 · Cited by 550
Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block
Wang, C., Takeuchi, K., Pinto, L. H., & Lamb, R. A. (1993) · Journal of Virology · doi:10.1128/jvi.67.9.5585-5594.1993 · Cited by 494
In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation
Bouvet, M., Debarnot, C., Imbert, I., Selisko, B., Snijder, E. J., Canard, B., & Decroly, E. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000863 · Cited by 406
Metadata
- Authors
- DeLean, A., Munson, P. J., & Rodbard, D.
- Venue
- American Journal of Physiology-Endocrinology and Metabolism
- Publisher
- American Physiological Society
- Published
- 1978-08-01
- Volume
- 235
- Issue
- 2
- Pages
- E97
- ISSN
- 0193-1849 (ISSN-L)
- 1522-1555
- OpenAlex
- W1936333617
- Cited by
- 2,374
- References
- 12
- FWCI
- 3.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. https://app.cochat.ai/papers/10.1152/ajpendo.1978.235.2.e97
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- DeLean, A., Munson, P. J., & Rodbard, D. (1978). Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. American Journal of Physiology-Endocrinology and Metabolism. https://doi.org/10.1152/ajpendo.1978.235.2.e97
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
