Assessment of intraluminal impedance for the detection of pharyngeal bolus flow during swallowing in healthy adults
Abstract
Intraluminal impedance, a nonradiological method for assessing bolus flow within the gut, may be suitable for investigating pharyngeal disorders. This study evaluated an impedance technique for the detection of pharyngeal bolus flow during swallowing. Patterns of pharyngoesophageal pressure and impedance were simultaneously recorded with videofluoroscopy in 10 healthy volunteers during swallowing of liquid, semisolid, and solid boluses. The timing of bolus head and tail passage recorded by fluoroscopy was correlated with the timing of impedance drop and recovery at each recording site. Bolus swallowing produced a drop in impedance from baseline followed by a recovery to at least 50% of baseline. The timing of the pharyngeal and esophageal impedance drop correlated with the timing of the arrival of the bolus head. In the pharynx, the timing of impedance recovery was delayed relative to the timing of clearance of the bolus tail. In contrast, in the upper esophageal sphincter (UES) and proximal esophagus, the timing of impedance recovery correlated well with the timing of clearance of the bolus tail. Impedance-based estimates of pharyngoesophageal bolus clearance time correlated with true pharyngoesophageal bolus clearance time. Patterns of intraluminal impedance recorded in the pharynx during bolus swallowing are therefore more complex than those in the esophagus. During swallowing, mucosal contact between the tongue base and posterior pharyngeal wall prolongs the duration of pharyngeal impedance drop, leading to overestimation of bolus tail timing. Therefore, we conclude that intraluminal impedance measurement does not accurately reflect the bolus transit in the pharynx but does accurately reflect bolus transit across the UES and below.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Combining pressure measurement with impedance measurement provides an assessment of both motility and flow of luminal content.
“Combining pressure measurement with impedance measurement provides an assessment of both motility and flow of luminal content.5”
From Artificial neural network classification of pharyngeal high‐resolution manometry with impedance data (2013) · cites this paper as [5]
Videofluoroscopy is traditionally considered the gold standard for evaluating aspiration but requires radiation exposure and is a fairly poor predictor of aspiration pneumonia.
“Videofluoroscopy has traditionally been considered the gold standard for evaluating aspiration, but requires radiation exposure and is a fairly poor predictor of aspiration pneumonia.5,13,14”
From Artificial neural network classification of pharyngeal high‐resolution manometry with impedance data (2013) · cites this paper as [5]
While impedance may not reliably measure pharyngeal bolus transit time, it can provide information on the presence or absence of pharyngeal bolus residue.
“While impedance may not reliably measure pharyngeal bolus transit time,5 it can provide information on the presence or absence of pharyngeal bolus residue.7-8”
From Artificial neural network classification of pharyngeal high‐resolution manometry with impedance data (2013) · cites this paper as [5]
Cites
Sifrim, D. A., Holloway, R. H., Silny, J., Xin, Z., Tack, J. F., Lerut, A., & Janssens, J. (2001) · Gastroenterology · doi:10.1053/gast.2001.24841 · Cited by 400 · see citing works
Tutuian, R. I., & Castell, D. O. (2004) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2004.30035.x · Cited by 259 · see citing works
Relevance of ineffective oesophageal motility during oesophageal acid clearance
Simrén, M., Silny, J., Holloway, R., et al. (2003) · Gut · doi:10.1136/gut.52.6.784 · Cited by 231 · see citing works
Sifrim, D. A., Silny, J., Holloway, R. H., et al. (1999) · Gut · doi:10.1136/gut.44.1.47 · Cited by 228 · see citing works
Composition of the postprandial refluxate in patients with gastroesophageal reflux disease
Sifrim, D. A., Holloway, R. H., Silny, J., et al. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.03598.x · Cited by 217 · see citing works
Fass, J., Silny, J., Braun, J., Heindrichs, U., Dreuw, B., Schumpelick, V., & Rau, G. (1994) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529409092496 · Cited by 114 · see citing works
Shay, S. S., Bomeli, S. R., & Richter, J. E. (2002) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00470.2001 · Cited by 81 · see citing works
Space-time pressure structure of pharyngo-esophageal segment during swallowing
Williams, R. B. H., Pal, A., Brasseur, J. G., & Cook, I. J. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.281.5.g1290 · Cited by 72 · see citing works
Self-citationTutuian, R. I., Elton, J. P., Castell, D. O., et al. (2003) · Neurogastroenterology & Motility · doi:10.1046/j.1365-2982.2003.00387.x · Cited by 54 · see citing works
Impedance characteristics of normal oesophageal motor function
Nguyen, H. N., Domingues, G. R., Winograd, R., Koppitz, P., Lammert, F., Silny, J., & Matern, S. (2003) · European Journal of Gastroenterology & Hepatology · doi:10.1097/01.meg.0000059161.46867.2b · Cited by 32 · see citing works
Is ineffective peristalsis really ineffective?
Nguyen, N. Q., Rigda, R., Tippett, M., et al. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)80801-6 · Cited by 3 · see citing works
Approval of Enteryx for GERD recommended by FDA panel
(2003) · Gastroenterology · doi:10.1016/s0016-5085(03)00660-7 · Cited by 2 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
A Method to Objectively Assess Swallow Function in Adults With Suspected Aspiration
Omari, T. I., Dejaeger, E., van Beckevoort, D., Goeleven, A., Davidson, G. P., Dent, J., Tack, J., & Rommel, N. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.02.051 · Cited by 142 · see citing works
Self-citationArtificial neural network classification of pharyngeal high‐resolution manometry with impedance data
Hoffman, M. R., Mielens, J. D., Omari, T. I., Rommel, N., Jiang, J. J., & McCulloch, T. M. (2013) · The Laryngoscope · doi:10.1002/lary.23655 · Cited by 34 · see citing works
Self-citation
- Authors
- Omari, T. I., Rommel, N., Szczesniak, M. M., Fuentealba, S., Dinning, P. G., Davidson, G. P., & Cook, I. J.
- Affiliations
- Women's and Children's Hospital (AU)
- UNSW Sydney (AU)
- The University of Adelaide (AU)
- Venue
- American Journal of Physiology-Gastrointestinal and Liver Physiology
- Publisher
- American Physiological Society
- Published
- 2006-01
- Volume
- 290
- Issue
- 1
- Pages
- G183-G188
- ISSN
- 0193-1857 (ISSN-L)
- 1522-1547
- OpenAlex
- W2110684931
- Cited by
- 53
- References
- 12
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 2 · 2021: 4 · 2019: 3 · 2018: 4 · 2017: 5 · 2016: 2 · 2015: 4 · 2014: 4 · 2013: 5 · 2012: 6
- FWCI
- 4.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Physiology-Gastrointestinal and Liver Physiology (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Flinders Academic Commons (Flinders University) (submittedVersion)
- Topics
- Health Sciences › Health Professions › Speech and Hearing › Dysphagia Assessment and Management
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- intraluminal impedance, swallowing, upper esophageal sphincter, pharyngeal disorders, videofluoroscopy
- MeSH terms
- Adult, Deglutition, Esophagus, Female, Health, Humans, Male, Manometry, Pharyngeal Diseases, Pharynx, Pressure
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
