The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Epithelial Cells and Their Neighbors I. Role of intestinal myofibroblasts in development, repair, and cancer
Abstract
Intestinal myofibroblasts are α-smooth muscle actin-positive stromal cells that exist as a syncytium with fibroblasts and mural cells in the lamina propria of the gut. Through expression and secretion of cytokines, chemokines, growth factors, prostaglandins, and basal lamina/extracellular matrix molecules, as well as expression of adhesion molecules and receptors for many of the same soluble factors and matrix, myofibroblasts mediate information flow between the epithelium and the mesenchymal elements of the lamina propria. With the use of these factors and receptors, they play a fundamental role in intestinal organogenesis and in the repair of wounding or disease. Intestinal neoplasms enlist and conscript myofibroblast factors and matrix molecules to promote neoplastic growth, carcinoma invasion, and distant metastases.
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Cites
Bone-marrow-derived myofibroblasts contribute to the cancer-induced stromal reaction
Ishii, G., Sangai, T., Oda, T., Aoyagi, Y., Hasebe, T., Kanomata, N., Endoh, Y., Okumura, C., Okuhara, Y., Magae, J., et al. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)01544-4 · Cited by 281
Decorin prevents metastatic spreading of breast cancer
Reed, C. C., Waterhouse, A., Kirby, S., Kay, P., Owens, R. T., McQuillan, D. J., & Iozzo, R. V. (2005) · Oncogene · doi:10.1038/sj.onc.1208329 · Cited by 209
Cited by
Stromal myofibroblasts are drivers of invasive cancer growth
De Wever, O., Demetter, P., Mareel, M., & Bracke, M. (2008) · International Journal of Cancer · doi:10.1002/ijc.23925 · Cited by 722
Cancer associated fibroblasts (CAFs) in tumor microenvironment
Xing, F. (2010) · Frontiers in Bioscience · doi:10.2741/3613 · Cited by 682
Hedgehog Signaling in Development and Homeostasis of the Gastrointestinal Tract
van den Brink, G. R. (2007) · Physiological Reviews · doi:10.1152/physrev.00054.2006 · Cited by 301
Deng, L., Jiang, N., Zeng, J., Wang, Y., & Cui, H. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.733270 · Cited by 51
Fotsitzoudis, C., Koulouridi, A., Messaritakis, I., Konstantinidis, T., Gouvas, N., Tsiaoussis, J., & Souglakos, J. (2022) · Cancers · doi:10.3390/cancers14184394 · Cited by 46
Metadata
- Authors
- Powell, D. W., Adegboyega, P. A., Di Mari, J. F., & Mifflin, R. C.
- Venue
- American Journal of Physiology-Gastrointestinal and Liver Physiology
- Publisher
- American Physiological Society
- Published
- 2005-07
- Volume
- 289
- Issue
- 1
- Pages
- G2-G7
- ISSN
- 0193-1857 (ISSN-L)
- 1522-1547
- OpenAlex
- W2107217007
- Cited by
- 223
- References
- 2
- FWCI
- 6.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Epithelial Cells and Their Neighbors I. Role of intestinal myofibroblasts in development, repair, and cancer. https://app.cochat.ai/papers/10.1152/ajpgi.00075.2005
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- Powell, D. W., Adegboyega, P. A., Di Mari, J. F., & Mifflin, R. C. (2005). Epithelial Cells and Their Neighbors I. Role of intestinal myofibroblasts in development, repair, and cancer. American Journal of Physiology-Gastrointestinal and Liver Physiology. https://doi.org/10.1152/ajpgi.00075.2005
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