Physiological characterization of gastric emptying using high-resolution antropyloroduodenal manometry
Open accessAbstract
High-resolution antropyloroduodenal manometry (HR-ADM) allows precise characterization of antral, pyloric, and duodenal motility, although its association with gastric emptying (GE) has been poorly investigated. Concurrent HR-ADM with GE measurement showed a lower frequency of antral postprandial contractions and an increased frequency of postprandial pylorospasms in patients with delayed GE. HR-ADM could, therefore, be useful in the future to better select patients for treatments targeting the pylorus.
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Advanced techniques, including antroduodenal‐jejunal manometry, wireless motility capsule, gastric ultrasound, and high‐resolution electrogastrography (EGG), may provide additional pathophysiological insight, particularly in complex or mixed‐pattern cases.
“Advanced techniques, including antroduodenal‑jejunal manometry [71–75], wireless motility capsule [76–79], gastric ultrasound [80–82], and high‑resolution electrogastrography (EGG) [83–87] may provide additional pathophysiological insight, particularly in complex or mixed‑pattern cases.”
From Diabetic gastroparesis: pathophysiology and impact on insulin timing choices (2026) · cites this paper as [73]
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Cites
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Shin, A. (2024) · The Lancet Gastroenterology & Hepatology · doi:10.1016/s2468-1253(24)00231-0 · Cited by 30 · see citing works
GASTROINTESTINAL MANIFESTATIONS OF SYSTEMIC SCLEROSIS: CURRENT APPROACHES AND EMERGING THERAPIES
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Varghese, C., & O’Grady, G. (2025) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2025.2549376 · Cited by 7 · see citing works
Electromechanical coupling across the gastroduodenal junction
Simmonds, S., Huizinga, J., Taberner, A., Du, P., & Angeli-Gordon, T. (2025) · Acta Physiologica · doi:10.1111/apha.70008 · Cited by 5 · see citing works
“135 In a mixed population of IBS and/or functional dyspepsia and non-specified patients, normal motor patterns were observed with some quantitative differences, such as fewer contractions propagating from the antrum into the duodenum, though no abnormal pyloric activities were reported.”
Chartier, M., Duboc, H., Moszkowicz, D., Dior, M., le Gall, M., Coffin, B., & Soliman, H. (2024) · Clinics And Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2024.102481 · Cited by 3 · see citing works
Self-citationDiabetic gastroparesis: pathophysiology and impact on insulin timing choices
Galeano, F., Tumminia, A., Oteri, V., Le Moli, R., Piticchio, T., Scilletta, S., Di Marco, M., Di Pino, A., & Frasca, F. (2026) · Endocrine · doi:10.1007/s12020-026-04693-6
Wang, X.-K., Camilleri, M., & Liu, Z.-M. (2026) · Neurogastroenterology and Motility · doi:10.1111/nmo.70454
“However, the procedure requires intubation and specialized expertise limited to few tertiary centers [14, 109, 111, 114].”
Tailored Prokinetic Therapy in Gastroparesis Using Gastric Emptying and Contractility
Ziyang, J. K., Kuo, B., & Surjanhata, B. (2026) · Neurogastroenterology and Motility · doi:10.1111/nmo.70463
“The role of the antropyloroduodenal coordination is crucial [20].”
Amoyel, M., Lebtahi, R., Poghosyan, T., le Gall, M., & Soliman, H. (2026) · Comprehensive Physiology · doi:10.1002/cph4.70275
Self-citationOsgood, P. T., Hoffmann, N. V., Wechsler, J., Pantazopoulos, R. S., & Fortunato, J. E. (2026) · Neurogastroenterology and Motility · doi:10.1111/nmo.70303
“While impaired pyloric relaxation is also often demonstrated in adults, impaired post-prandial antral contractions may also contribute to delayed GE and symptomatology [40], a finding not observed within our pediatric cohort.”
Ultrasound-based assessment of impaired gastric emptying in patients with hepatitis B cirrhosis
Li, H., Luo, Y.-H., Zhang, Q., Dong, L.-H., Liu, H., Yue, W.-S., Zhu, Q.-R., & Huang, D. (2025) · Clinical and Experimental Medicine (Testo stampato) · doi:10.1007/s10238-025-01650-x
“These challenges stem from several factors, such as the high cost of equipment and examination, the invasive nature, the time-consuming aspect, and the complexity of result interpretation [4, 13–16].”
- Authors
- Soliman, H., Wuestenberghs, F., Desprez, C., Leroi, A.-M., Melchior, C., & Gourcerol, G.
- Affiliations
- Inserm (FR)
- Corresponding author
- Soliman, Heithem
- ORCID
- Venue
- American Journal of Physiology-Gastrointestinal and Liver Physiology
- Publisher
- American Physiological Society
- Published
- 2024-01-01
- Volume
- 326
- Issue
- 1
- Pages
- G16-G24
- ISSN
- 0193-1857 (ISSN-L)
- 1522-1547
- OpenAlex
- W4387909012
- Cited by
- 15
- References
- 0
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 4
- FWCI
- 4.28
- Type
- journal article
- Language
- en
- Open access
- Licence
- public-domain
- Locations
- American Journal of Physiology-Gastrointestinal and Liver Physiology (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, public-domain)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
- Keywords
- gastric emptying, antral motility, pyloric motility, duodenal motility, pylorospasm, delayed gastric emptying
- MeSH terms
- Duodenum, Gastric Emptying, Gastrointestinal Motility, Humans, Manometry, Pyloric Antrum, Pylorus
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