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Cited by 38Lymphatic System and DiseasesLymphatic Disorders and TreatmentsParasitic Diseases Research and Treatment

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Adaptation of mesenteric lymphatic vessels to prolonged changes in transmural pressure

Open access
Dongaonkar, R. M., Nguyen, T. L., Quick, C. M., Hardy, J., Laine, G. A., Wilson, E., Stewart, R. H.·2013·American Journal of Physiology-Heart and Circulatory Physiology
DOI 10.1152/ajpheart.00677.2012PMC PMC3726955
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Abstract

In vitro studies have revealed that acute increases in transmural pressure increase lymphatic vessel contractile function. However, adaptive responses to prolonged changes in transmural pressure in vivo have not been reported. Therefore, we developed a novel bovine mesenteric lymphatic partial constriction model to test the hypothesis that lymphatic vessels exposed to higher transmural pressures adapt functionally to become stronger pumps than vessels exposed to lower transmural pressures. Postnodal mesenteric lymphatic vessels were partially constricted for 3 days. On postoperative day 3, constricted vessels were isolated, and divided into upstream (UP) and downstream (DN) segment groups, and instrumented in an isolated bath. Although there were no differences between the passive diameters of the two groups, both diastolic diameter and systolic diameter were significantly larger in the UP group than in the DN group. The pump index of the UP group was also higher than that in the DN group. In conclusion, this is the first work to report how lymphatic vessels adapt to prolonged changes in transmural pressure in vivo. Our results suggest that vessel segments upstream of the constriction adapt to become both better fluid conduits and lymphatic pumps than downstream segments.

Overview

Integrity signals

Registry

Crossref · 10.1152/ajpheart.00677.2012

Cites

45 of 45 references verified0 citation errors · 0 not checkable

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Citations

Cites

Research works printed but not linked: 5

  1. Campbell T, 1973, Q J Exp Physiol Cogn Med Sci, 207
  2. Gashev AA, 2001, Lymphology, 34, 124
  3. Mawhinney HJ, 1971, J Physiol, 219, 34P
  4. McHale N, 1975, J Physiol, 244, 70
  5. Mulvany MJ, 1996, Hypertension, 28, 505

Cited by

See all 38

Metadata

Authors
Dongaonkar, R. M., Nguyen, T. L., Quick, C. M., Hardy, J., Laine, G. A., Wilson, E., & Stewart, R. H.
Affiliations
  • Texas A&M University (US)
  • Texas A&M Health Science Center (US)
Corresponding author
Quick, C. M.
ORCID
Venue
American Journal of Physiology-Heart and Circulatory Physiology
Publisher
American Physiological Society
Published
2013-07-15
Volume
305
Issue
2
Pages
H203-H210
ISSN
  • 0363-6135 (ISSN-L)
  • 1522-1539
DOI
10.1152/ajpheart.00677.2012
PMC
PMC3726955
OpenAlex
W2123317934
Cited by
38
References
45
Citations by year
2026: 1 · 2025: 1 · 2024: 4 · 2023: 2 · 2022: 2 · 2021: 4 · 2020: 3 · 2019: 3 · 2018: 3 · 2017: 1 · 2016: 3 · 2015: 2 · 2014: 4 · 2013: 5
FWCI
2.50
Type
journal article
Language
en
Open access
Locations
  • American Journal of Physiology-Heart and Circulatory Physiology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Heart, Lung, and Blood Institute (R01HL092916, HL-092916)
Topics
  • Health Sciences › Medicine › Oncology › Lymphatic System and Diseases
  • Health Sciences › Medicine › Surgery › Lymphatic Disorders and Treatments
  • Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
Keywords
mesenteric lymphatics, transmural pressure, vascular adaptation, lymphatic vessel diameter, bovine model
MeSH terms
Adaptation, Physiological, Animals, Cattle, Constriction, Lymphedema, Mesentery, Muscle Contraction, Pressure, Time Factors, Lymphatic Vessels

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.