The DOI matches its Crossref record.
Impaired muscle glycogen resynthesis after eccentric exercise
Abstract
Eight men performed 10 sets of 10 eccentric contractions of the knee extensor muscles with one leg [eccentrically exercised leg (EL)]. The weight used for this exercise was 120% of the maximal extension strength. After 30 min of rest the subjects performed two-legged cycling [concentrically exercised leg (CL)] at 74% of maximal O2 uptake for 1 h. In the 3 days after this exercise four subjects consumed diets containing 4.25 g CHO/kg body wt, and the remainder were fed 8.5 g CHO/kg. All subjects experienced severe muscle soreness and edema in the quadriceps muscles of the eccentrically exercised leg. Mean (+/- SE) resting serum creatine kinase increased from a preexercise level of 57 +/- 3 to 6,988 +/- 1,913 U/l on the 3rd day of recovery. The glycogen content (mmol/kg dry wt) in the vastus lateralis of CL muscles averaged 90, 395, and 592 mmol/kg dry wt at 0, 24, and 72 h of recovery. The EL muscle, on the other hand, averaged 168, 329, and 435 mmol/kg dry wt at these same intervals. Subjects receiving 8.5 g CHO/kg stored significantly more glycogen than those who were fed 4.3 g CHO/kg. In both groups, however, significantly less glycogen was stored in the EL than in the CL.
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“isolated eccentric exercise (29) or exhaustive running (14) was associated with reduced rates of muscle glycogen restoration during 24 and 72 h of post-exercise recovery”
From Postexercise muscle glycogen resynthesis in humans. (2017) · cites this paper as [29]
In the citing paper
“glycogen synthesis in damaged muscles might be partially overcome by increased amounts of CHO intake during the first 24 h after exercise (29).”
From Postexercise muscle glycogen resynthesis in humans. (2017) · cites this paper as [29]
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Metadata
- Authors
- Costill, D. L., Pascoe, D. D., Fink, W. J., Robergs, R. A., Barr, S. I., & Pearson, D.
- Affiliations
- Ball State University (US)
- ORCID
- Robergs, R. A.
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 1990-07-01
- Volume
- 69
- Issue
- 1
- Pages
- 46-50
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2097845617
- Cited by
- 173
- References
- 0
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 6 · 2020: 5 · 2019: 4 · 2018: 6 · 2017: 7 · 2016: 7 · 2015: 5 · 2014: 5 · 2013: 9 · 2012: 7
- FWCI
- 2.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Applied Physiology (publishedVersion)
- PubMed (publishedVersion)
- QUT ePrints (Queensland University of Technology) (submittedVersion)
- Faculty of Health
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Keywords
- muscle glycogen resynthesis, eccentric exercise, post-exercise recovery, carbohydrate intake, creatine kinase, delayed onset muscle soreness, muscle edema, vastus lateralis, knee extensors
- MeSH terms
- Adult, Dietary Carbohydrates, Glycogen, Humans, Male, Muscle Contraction, Muscles, Time Factors, Exercise
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