Cited by 173Muscle metabolism and nutritionExercise and Physiological ResponsesCardiovascular and exercise physiology

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Impaired muscle glycogen resynthesis after eccentric exercise

Costill, D. L., Pascoe, D. D., Fink, W. J., Robergs, R. A., Barr, S. I., Pearson, D.·1990·Journal of Applied Physiology

DOI 10.1152/jappl.1990.69.1.46

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Abstract

Eight men performed 10 sets of 10 eccentric contractions of the knee extensor muscles with one leg [eccentrically exercised leg (EL)]. The weight used for this exercise was 120% of the maximal extension strength. After 30 min of rest the subjects performed two-legged cycling [concentrically exercised leg (CL)] at 74% of maximal O2 uptake for 1 h. In the 3 days after this exercise four subjects consumed diets containing 4.25 g CHO/kg body wt, and the remainder were fed 8.5 g CHO/kg. All subjects experienced severe muscle soreness and edema in the quadriceps muscles of the eccentrically exercised leg. Mean (+/- SE) resting serum creatine kinase increased from a preexercise level of 57 +/- 3 to 6,988 +/- 1,913 U/l on the 3rd day of recovery. The glycogen content (mmol/kg dry wt) in the vastus lateralis of CL muscles averaged 90, 395, and 592 mmol/kg dry wt at 0, 24, and 72 h of recovery. The EL muscle, on the other hand, averaged 168, 329, and 435 mmol/kg dry wt at these same intervals. Subjects receiving 8.5 g CHO/kg stored significantly more glycogen than those who were fed 4.3 g CHO/kg. In both groups, however, significantly less glycogen was stored in the EL than in the CL.

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Method
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Background
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Background
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Background
Carbohydrates and exercise
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Method
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Self-citation
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Authors: Costill, D. L., Pascoe, D. D., Fink, W. J., Robergs, R. A., Barr, S. I., & Pearson, D.
Affiliations: Ball State University (US)
ORCID: Robergs, R. A.
Venue: Journal of Applied Physiology
Publisher: American Physiological Society
Published: 1990-07-01
Volume: 69
Issue: 1
Pages: 46-50
ISSN: 0161-7567 (ISSN-L)
8750-7587
1522-1601
DOI: 10.1152/jappl.1990.69.1.46
OpenAlex: W2097845617
Cited by: 173
References: 0
Citations by year: 2026: 2 · 2025: 2 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 6 · 2020: 5 · 2019: 4 · 2018: 6 · 2017: 7 · 2016: 7 · 2015: 5 · 2014: 5 · 2013: 9 · 2012: 7
FWCI: 2.08
Type: journal article
Language: en
Open access: closed
Locations: Journal of Applied Physiology (publishedVersion)
PubMed (publishedVersion)
QUT ePrints (Queensland University of Technology) (submittedVersion)
Faculty of Health
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Keywords: muscle glycogen resynthesis, eccentric exercise, post-exercise recovery, carbohydrate intake, creatine kinase, delayed onset muscle soreness, muscle edema, vastus lateralis, knee extensors
MeSH terms: Adult, Dietary Carbohydrates, Glycogen, Humans, Male, Muscle Contraction, Muscles, Time Factors, Exercise

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Impaired muscle glycogen resynthesis after eccentric exercise

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