Commentary on viewpoint: Perspective on the future use of genomics in exercise prescription.
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Exercise prescription is the key for dosing and for individualization of acute physical exercises and physical training.
“Furthermore, exercise prescription is the key for dosing (Wasfy and Baggish, 2016; Pontifex et al., 2018) and for individualization of acute physical exercises and physical training (Lightfoot, 2008).”
From Dose-Response Matters! - A Perspective on the Exercise Prescription in Exercise-Cognition Research (2019) · cites this paper as Lightfoot, 2008
All scientific disciplines studying the relationship between physical exercises and/or physical training and the central nervous system are based on an appropriate exercise prescription that specifies exercise and/or training variables.
“Although these different scientific disciplines use different approaches to understand the relationship between physical exercises and/or physical training and the central nervous system, it is undoubted that all of them are based on an appropriate exercise prescription that specifies exercise (e.g., exercise intensity, exercise duration) and/or training variables (e.g., frequency of training ses”
From Dose-Response Matters! - A Perspective on the Exercise Prescription in Exercise-Cognition Research (2019) · cites this paper as Lightfoot, 2008
Analysis of the genetics of participants is helpful in supporting individualization of acute physical exercise and/or physical training by aiding the identification of potential responders and non-responders.
“However, analysis of the genetics of participants is undoubtedly helpful in supporting individualization of acute physical exercise and/or physical training by aiding, for instance, the identification of potential responders and non-responders (Lightfoot, 2008; Pescatello, 2008; Booth and Laye, 2010; Timmons et al., 2010; Timmons, 2011; Pickering and Kiely, 2019a, b).”
From Dose-Response Matters! - A Perspective on the Exercise Prescription in Exercise-Cognition Research (2019) · cites this paper as Lightfoot, 2008
Individualization of acute physical exercises and/or physical training could be achieved by adjusting the exercise prescription, such as exercise intensity, which influences the dose.
“Such an individualization of acute physical exercises and/or physical training could be achieved by adjusting the exercise prescription (e.g., exercise intensity) (Lightfoot, 2008), which influences, in turn, the dose”
From Dose-Response Matters! - A Perspective on the Exercise Prescription in Exercise-Cognition Research (2019) · cites this paper as Lightfoot, 2008
Cites
Sports Participation during Adolescence: A Shift from Environmental to Genetic Factors
STUBBE, J. H., BOOMSMA, D. I., & DE GEUS, E. J. C. (2005) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000158181.75442.8b · Cited by 165 · see citing works
Finkelstein, E. A., Linnan, L. A., Tate, D. F., & Birken, B. E. (2007) · Journal of Occupational & Environmental Medicine · doi:10.1097/jom.0b013e31813c6dcb · Cited by 149 · see citing works
Quantitative trait loci for physical activity traits in mice
Lightfoot, J. T., Turner, M. J., Pomp, D., Kleeberger, S. R., & Leamy, L. J. (2008) · Physiological Genomics · doi:10.1152/physiolgenomics.00241.2007 · Cited by 103 · see citing works
Self-citationPerspective on the future use of genomics in exercise prescription
Roth, S. M. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01000.2007 · Cited by 41 · see citing works
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Garland, T., Schutz, H., Chappell, M. A., Keeney, B. K., Meek, T. H., Copes, L. E., Acosta, W., Drenowatz, C., Maciel, R. C., van Dijk, G., et al. (2011) · Journal of Experimental Biology · doi:10.1242/jeb.048397 · Cited by 444 · see citing works
Dose-Response Matters! - A Perspective on the Exercise Prescription in Exercise-Cognition Research
Herold, F., Müller, P., Gronwald, T., & Müller, N. G. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.02338 · Cited by 196 · see citing works
Perspective of Dose and Response for Individualized Physical Exercise and Training Prescription
Gronwald, T., Törpel, A., Herold, F., & Budde, H. (2020) · Journal of Functional Morphology and Kinesiology · doi:10.3390/jfmk5030048 · Cited by 73 · see citing works
Herold, F., Törpel, A., Hamacher, D., Budde, H., Zou, L., Strobach, T., Müller, N. G., & Gronwald, T. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.682891 · Cited by 73 · see citing works
Genetic architecture of voluntary exercise in an advanced intercross line of mice
Kelly, S. A., Nehrenberg, D. L., Peirce, J. L., Hua, K., Steffy, B. M., Wiltshire, T., de Villena, F. P., Garland, T., & Pomp, D. (2010) · Physiological Genomics · doi:10.1152/physiolgenomics.00028.2010 · Cited by 63 · see citing works
Genetics and sport performance: current challenges and directions to the future
Guilherme, J. P. L. F., Tritto, A. C., North, K. N., Lancha, A. H., & Artioli, G. G. (2014) · Revista Brasileira de Educação Física e Esporte · doi:10.1590/s1807-55092014000100177 · Cited by 57 · see citing works
Commentary: Physical Exercise as Personalized Medicine for Dementia Prevention?
Gronwald, T., & Budde, H. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01358 · Cited by 20 · see citing works
- Authors
- Lightfoot, J. T.
- Affiliations
- University of North Carolina at Charlotte (US)
- Corresponding author
- Lightfoot, J. Timothy
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 2008-04
- Volume
- 104
- Issue
- 4
- Pages
- 1249-1249
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2077330427
- Cited by
- 7
- References
- 4
- Citations by year
- 2021: 1 · 2020: 1 · 2019: 2 · 2014: 1
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Applied Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Physical Performance
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Nutrition, Genetics, and Disease
- Keywords
- exercise prescription, genomics, personalized exercise, genetic variation
- MeSH terms
- Humans, Physical Fitness, Biomarkers, Exercise, Exercise Tolerance, Genomics, Prescriptions
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