The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Long-term potentiation of horizontal connections provides a mechanism to reorganize cortical motor maps
Abstract
1. Field potential recordings were used in rat motor cortex (MI) slice preparations to investigate the potential for activity-dependent modifications in the effectiveness of synaptic connections formed by layer II/III horizontal projections. 2. Long-term potentiation (LTP) of synaptic efficacy in MI horizontal pathways could be produced at short (0.5 mm) and long (1.0 mm) distances by theta burst stimulation (TBS), but only during local, transient application of the gamma-aminobutyric acid-A (GABAA) receptor antagonist, bicuculline methiodide (bic) immediately before TBS. Mean increase of the field potential amplitude measured 25–35 min after LTP induction ranged between 24 and 34%. Cooperative effects of conjoint TBS of two horizontal pathways on LTP induction were observed. 3. These results demonstrate that persistent changes in the functional interactions of cortical neurons can arise by activity-dependent mechanisms within the local horizontal connections and suggest a likely mechanism to recognize cortical representation patterns.
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Cites
Dynamics of the Hippocampal Ensemble Code for Space
Wilson, M. A., & McNaughton, B. L. (1993) · Science · doi:10.1126/science.8351520 · Cited by 2,350
Seitz, R. J., & Roland, P. E. (1992) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1992.tb00862.x · Cited by 321 · cited 1×
“…blood flow and lowering of movement stimulation thresholds in human motor cortex that accompany motor learning (Grafton et al. 1992; Pascual-Leone et al. 1993; Seitz and Roland 1992) suggest that neuronal activity is markedly increased in cortical motor circuits in association with skill learning.”
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Cited by
Physiological basis of transcranial direct current stimulation
Stagg, C. J., & Nitsche, M. A. (2011) · The Neuroscientist · doi:10.1177/1073858410386614 · Cited by 1,719
Plasticity and Primary Motor Cortex
Sanes, J. N., & Donoghue, J. P. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.393 · Cited by 1,202
Self-citationVirtual Environments for Motor Rehabilitation: Review
Holden, M. K. (2005) · CyberPsychology & Behavior · doi:10.1089/cpb.2005.8.187 · Cited by 1,154
Plasticity of motor systems after incomplete spinal cord injury
Raineteau, O., & Schwab, M. E. (2001) · Nature Reviews Neuroscience · doi:10.1038/35067570 · Cited by 803
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Ridding, M. C., & Rothwell, J. C. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2169 · Cited by 687
Metadata
- Authors
- Hess, G., & Donoghue, J. P.
- Venue
- Journal of Neurophysiology
- Publisher
- American Physiological Society
- Published
- 1994-06-01
- Volume
- 71
- Issue
- 6
- Pages
- 2543-2547
- ISSN
- 0022-3077 (ISSN-L)
- 1522-1598
- OpenAlex
- W2431771327
- Cited by
- 376
- References
- 2
- FWCI
- 2.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hess, G., & Donoghue, J. P. (1994). Long-term potentiation of horizontal connections provides a mechanism to reorganize cortical motor maps. Journal of Neurophysiology. https://doi.org/10.1152/jn.1994.71.6.2543
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
