The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Signaling in Muscle Atrophy and Hypertrophy
Abstract
Muscle performance is influenced by turnover of contractile proteins. Production of new myofibrils and degradation of existing proteins is a delicate balance, which, depending on the condition, can promote muscle growth or loss. Protein synthesis and protein degradation are coordinately regulated by pathways that are influenced by mechanical stress, physical activity, availability of nutrients, and growth factors. Understanding the signaling that regulates muscle mass may provide potential therapeutic targets for the prevention and treatment of muscle wasting in metabolic and neuromuscular diseases.
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Self-citationAutophagy is required to maintain muscle mass.
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Metadata
- Authors
- Sandri, M.
- Venue
- Physiology
- Publisher
- American Physiological Society
- Published
- 2008-06
- Volume
- 23
- Issue
- 3
- Pages
- 160-170
- ISSN
- 0886-1714 (ISSN-L)
- 1548-9213
- 1548-9221
- OpenAlex
- W2165370562
- Cited by
- 827
- References
- 25
- FWCI
- 16.01
- Type
- journal article
- Language
- en
- Open access
- closed
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