The DOI matches its Crossref record.
A genome scan for QTL influencing milk production and health traits in dairy cattle
Abstract
Heyen, D. W., J. I. Weller, M. Ron, M. Band, J. E. Beever, E. Feldmesser, Y. Da, G. R. Wiggans, P. M. VanRaden, and H. A. Lewin. A genome scan for QTL influencing milk production and health traits in dairy cattle. Physiol. Genomics 1: 165–175, 1999.—A genome scan was conducted in the North American Holstein-Friesian population for quantitative trait loci (QTL) affecting production and health traits using the granddaughter design. Resource families consisted of 1,068 sons of eight elite sires. Genome coverage was estimated to be 2,551 cM (85%) for 174 genotyped markers. Each marker was tested for effects on milk yield, fat yield, protein yield, fat percentage, protein percentage, somatic cell score, and productive herd life using analysis of variance. Joint analysis of all families identified marker effects on 11 chromosomes that exceeded the genomewide, suggestive, or nominal significance threshold for QTL effects. Large marker effects on fat percentage were found on chromosomes 3 and 14, and multimarker regression analysis was used to refine the position of these QTL. Half-sibling families from Israeli Holstein dairy herds were used in a daughter design to confirm the presence of the QTL for fat percentage on chromosome 14. The QTL identified in this study may be useful for marker-assisted selection and for selection of a refined set of candidate genes affecting these traits.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Grisart, B., Coppieters, W., Farnir, F., Karim, L., Ford, C., Berzi, P., Cambisano, N., Mni, M., Reid, S., Simon, P., et al. (2002) · Genome Research · doi:10.1101/gr.224202 · Cited by 965
Grisart, B., Farnir, F., Karim, L., Cambisano, N., Kim, J.-J., Kvasz, A., Mni, M., Simon, P., Frère, J.-M., Coppieters, W., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308518100 · Cited by 447
Genetic dissection of phenotypic diversity in farm animals
Andersson, L. (2001) · Nature Reviews Genetics · doi:10.1038/35052563 · Cited by 425
Winter, A., Krämer, W., Werner, F. A. O., Kollers, S., Kata, S., Durstewitz, G., Buitkamp, J., Womack, J. E., Thaller, G., & Fries, R. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.142293799 · Cited by 403
Quantitative trait loci mapping in dairy cattle: review and meta-analysis
Khatkar, M. S., Thomson, P. C., Tammen, I., & Raadsma, H. W. (2004) · Genetics Selection Evolution · doi:10.1186/1297-9686-36-2-163 · Cited by 310
Metadata
- Authors
- HEYEN, D. W., WELLER, J. I., RON, M., BAND, M., BEEVER, J. E., FELDMESSER, E., DA, Y., WIGGANS, G. R., VanRADEN, P. M., & LEWIN, H. A.
- Venue
- Physiological Genomics
- Publisher
- American Physiological Society
- Published
- 1999-11-11
- Volume
- 1
- Issue
- 3
- Pages
- 165-175
- ISSN
- 1094-8341 (ISSN-L)
- 1531-2267
- OpenAlex
- W2164559559
- Cited by
- 219
- References
- 0
- FWCI
- 5.74
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A genome scan for QTL influencing milk production and health traits in dairy cattle. https://app.cochat.ai/papers/10.1152/physiolgenomics.1999.1.3.165
- The paper
- HEYEN, D. W., WELLER, J. I., RON, M., BAND, M., BEEVER, J. E., FELDMESSER, E., DA, Y., WIGGANS, G. R., VanRADEN, P. M., & LEWIN, H. A. (1999). A genome scan for QTL influencing milk production and health traits in dairy cattle. Physiological Genomics. https://doi.org/10.1152/physiolgenomics.1999.1.3.165
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
