The ACE2/angiotensin-(1-7)/MAS Axis of the renin-angiotensin system: focus on angiotensin-(1-7)

Santos, Robson Augusto Souza, Sampaio, Walkyria Oliveira, Alzamora, Andreia C., Motta-Santos, Daisy, Alenina, Natalia, Bader, Michael, Campagnole-Santos, Maria Jose·2018·Physiological Reviews

DOI 10.1152/physrev.00023.2016

Cites (642)

Items 201–400 of 642

Angiotensin type 2 receptor (AT2R) and receptor Mas: a complex liaison
Daniel Campos Villela, Julia Leonhardt, Neal Patel, Jason P. Joseph, Sebastian Kirsch, Anders Hallberg, Thomas Unger, Michael Bäder, Robson A.S. Santos, Colin Sumners et al. · 2014 · Clinical Science
Angiotensin1‐9 antagonises pro‐hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor
Mónica Flores‐Muñoz, Nicola J. Smith, C. Haggerty, Graeme Milligan, Stuart A. Nicklin · 2010 · The Journal of Physiology
Modulation of phospholipase A2 activity and sodium transport by angiotensin-(1-7)
Sheila Andreatta‐Van Leyen, Michael F. Romero, Mahesh C. Khosla · 1993 · Kidney International
Angiotensin-(1–7) Attenuates Neointimal Formation After Stent Implantation in the Rat
Bas Langeveld, Wiek H. van Gilst, René A. Tio, Felix Zijlstra, Anton J.M. Roks · 2004 · Hypertension
Cardiovascular effects produced by microinjection of angiotensins and angiotensin antagonists into the ventrolateral medulla of freely moving rats
Marco Antônio Peliky Fontes, Marli Cardoso Martins‐Pinge, V Naves · 1997 · Brain Research
Oral Formulation of Angiotensin-(1–7) Improves Lipid Metabolism and Prevents High-Fat Diet–Induced Hepatic Steatosis and Inflammation in Mice
John David Feltenberger, João Marcus Oliveira Andrade, Alanna Fernandes Paraíso, Lucas Oliveira Barros, Aristides Batista Maia Filho, Rubén D. Sinisterra, Frederico B. De Sousa, André Luiz Sena Guimarães, Alfredo Maurício Batista de Paula, Maria José Campagnole‐Santos et al. · 2013 · Hypertension
Expression and localization of the renin-angiotensin system in the rat pancreas
Po Sing Leung, WP Chan, T.P. Wong, Conrad Sernia · 1999 · Journal of Endocrinology
Angiotensin (1–7) and its receptor Mas are expressed in the human testis: implications for male infertility
Augusto Barbosa Reis, Fabiano Conde Araujo, Virgínia Mara Pereira · 2010 · Journal of Molecular Histology
Angiotensin-Converting Enzyme Inhibition Attenuates Lipopolysaccharide-Induced Lung Injury by Regulating the Balance Between Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 and Inhibiting Mitogen-Activated Protein Kinase Activation
Yingchuan Li, Zhen Zeng, Yachun Li · 2015 · Shock
Angiotensin-(1-7) improves oxygenation, while reducing cellular infiltrate and fibrosis in experimental Acute Respiratory Distress Syndrome
Vanessa Zambelli, Giacomo Bellani, Roberto Borsa, Federico Pozzi, Alice Grassi, Margherita Scanziani, Vittoria Castiglioni, Serge Masson, Alessandra Decio, John Gerard Laffey et al. · 2015 · Intensive Care Medicine Experimental
Angiotensin-Converting Enzyme 2 Is a Critical Determinant of Angiotensin II–Induced Loss of Vascular Smooth Muscle Cells and Adverse Vascular Remodeling
Vaibhav B. Patel, Jiuchang Zhong, Fan Dong, Ratnadeep Basu, Jude S. Morton, Nirmal Parajuli, Michael Sean McMurtry, Sandra Thomas Davidge, Zamaneh Kassiri, Gavin Y. Oudit · 2014 · Hypertension
A ngiotensin‐(1‐7) attenuates airway remodelling and hyperresponsiveness in a model of chronic allergic lung inflammation
Giselle Santos Magalhães, Maria da Glória Rodrigues‐Machado, Daisy Motta‐Santos, A R Silva, Marcelo Vidigal Caliari, Luana Oliveira Prata, Soraia Carvalho Abreu, Patrícia R. M. Rocco, Lucíola S. Barcelos, Robson A.S. Santos et al. · 2015 · British Journal of Pharmacology
Neuronal over-expression of ACE2 protects brain from ischemia-induced damage
Ji Chen, Yuhui Zhao, Shuzhen Chen, Jinju Wang, Xiang Xiao, Xiaotang Ma, Madhuri Penchikala, Huijing Xia, Eric D. Lazartigues, Bin Zhao et al. · 2014 · Neuropharmacology
Angiotensin-(1–7), an alternative metabolite of the renin–angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat
John Samuel Lubel, Chandana B. Herath, Jorge Tchongue, Josephine Grace, Zhiyuan Jia, Karen Spencer, David J. CASLEY, Peter F Crowley, William Sievert, Louise M. Burrell et al. · 2009 · Clinical Science
Activation of Local Chorionic Villi Angiotensin II Levels But Not Angiotensin (1-7) in Preeclampsia
Lauren Anton, David Merrill, Liomar A. A. Neves, Kathryn Stovall, Patricia E. Gallagher, Debra I. Diz, Cheryl Moorefield, Courtney Gruver, Carlos Maria Ferrario, K. Bridget Brosnihan · 2008 · Hypertension
Angiotensin-(1–7) Inhibitory Mechanism of Norepinephrine Release in Hypertensive Rats
Mariela Mercedes Gironacci, María S. Valera, Irène Yujnovsky · 2004 · Hypertension
Exercise training normalizes ACE and ACE2 in the brain of rabbits with pacing-induced heart failure
Sumit Kar, Lie Gao, Irving H. Zucker · 2010 · Journal of Applied Physiology
Angiotensin-(1–7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic mice
Yixuan Shi, Chao‐Sheng Lo, Ranjit Singh Padda · 2014 · Clinical Science
Mesenchymal Stem Cells Overexpressing Angiotensin-Converting Enzyme 2 Rescue Lipopolysaccharide-Induced Lung Injury
Hongli He, Ling Liu, Qihong Chen, Airan Liu, Shixia Cai, Yi Yang, Xiaomin Lu, Haibo Qiu · 2015 · Cell Transplantation
Role of Angiotensin-(1-7) in the Modulation of the Baroreflex in Renovascular Hypertensive Rats
Raquel Rodrigues Britto, Robson A.S. Santos, Cristiane R. Fagundes-Moura · 1997 · Hypertension
Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated <i>MuRF1</i> Expression
Du Bois, Philipp, Pablo Tortola, Cristina, Lodka, Doerte, Kny, Melanie, Schmidt, Franziska, Song, Kunhua, Schmidt, Sibylle, Bassel-Duby, Rhonda, Olson, Eric N., Fielitz, Jens · 2015 · Circulation Research
Up-regulation of the Angiotensin II Type 1 Receptor by the MAS Proto-oncogene Is Due to Constitutive Activation of Gq/G11 by MAS
Meritxell Canals, Laura Jenkins, Elaine Kellett · 2006 · Journal of Biological Chemistry
Bradykinin B2 receptor knockout mice are protected from thrombosis by increased nitric oxide and prostacyclin
Zia Shariat‐Madar, Fakhri Mahdi, Mark Warnock · 2006 · Blood
An evolving story of angiotensin-II-forming pathways in rodents and humans
Carlos Maria Ferrario, Sarfaraz Ahmad, Sayaka Nagata, Stephen Simington, Jasmina Varagić, Neal D. Kon, Louis J. Dell’Italia · 2013 · Clinical Science
Angiotensin-(1-7) Reduces Fibrosis in Orthotopic Breast Tumors
Katherine Loree Cook, Linda J. Metheny‐Barlow, Elisabeth Ann Tallant, Patricia E. Gallagher · 2010 · Cancer Research
Agonists of MAS oncogene and angiotensin II type 2 receptors attenuate cardiopulmonary disease in rats with neonatal hyperoxia-induced lung injury
Gerry T. M. Wagenaar, El Houari Laghmani, Melissa Fidder, Rozemarijn M. A. Sengers, Yvonne P. de Visser, Louwe de Vries, Rick Rink, Anton J.M. Roks, Gert Folkerts, Frans J. Walther · 2013 · American Journal of Physiology-Lung Cellular and Molecular Physiology
Changes in the Baroreflex Control of Heart Rate Produced by Central Infusion of Selective Angiotensin Antagonists in Hypertensive Rats
Djenane Ramalho de Oliveira, Robson A.S. Santos, Gláucia F.P. Santos · 1996 · Hypertension
Increased circulating angiotensin-(1–7) protects white adipose tissue against development of a proinflammatory state stimulated by a high-fat diet
Sérgio Henrique Sousa Santos, Luciana Rodrigues Fernandes, Camila Santos Pereira, André Luiz Sena Guimarães, Alfredo Maurício Batista de Paula, Maria José Campagnole‐Santos, Jacqueline Isaura Alvarez-Leite, Michael Bäder, Robson A.S. Santos · 2012 · Regulatory Peptides
Immunocytochemical localization of angiotensin-(1–7) in the rat forebrain
Christine H. Block, Robson A.S. Santos, K. Bridget Brosnihan, Carlos Maria Ferrario · 1988 · Peptides
Angiotensin metabolites can stimulate receptors of the Mas-related genes family
Florian Gembardt, S. Grajewski, Martin Vahl, Heinz‐Peter Schultheiss, Thomas Walther · 2008 · Molecular and Cellular Biochemistry
Captopril and Enalapril Improve Cognition and Depressed Mood in Hypertensive Patients
Braszko,, J.J., Karwowska-Polecka,, W., Halicka,, D., Gard,, P.R. · 2003 · Journal of Basic and Clinical Physiology and Pharmacology
Comparative effects of angiotensin-(1-7) and angiotensin II on piglet pial arterioles.
W Meng, David W. Busija · 1993 · Stroke
Characterization of a New Selective Antagonist for Angiotensin-(1–7), d -Pro 7 -Angiotensin-(1–7)
Robson A.S. Santos, Andréa Siqueira Haibara, Maria José Campagnole‐Santos et al. · 2003 · Hypertension
Angiotensin-(1-7) and the Rat Aorta: Modulation by the Endothelium
Yen le Tran, Christine M. Forster · 1997 · Journal of Cardiovascular Pharmacology
Gonadotropin Stimulation Increases the Expression of Angiotensin-(1–7) and Mas Receptor in the Rat Ovary
Pereira, Virgínia M., Reis, Fernando M., Santos, Robson A. S., Cassali, Geovanni D., Santos, Sérgio H. S., Honorato-Sampaio, Kinulpe, dos Reis, Adelina M. · 2009 · Reproductive Sciences
Angiotensin-Converting Enzyme 2 Deficiency Is Associated With Impaired Gestational Weight Gain and Fetal Growth Restriction
Manish S. Bharadwaj, William B. Strawn, Leanne Groban, Liliya M. Yamaleyeva, Mark C. Chappell, Carina Horta, Katie Atkins, Luciana Barbosa Firmes, Susan B. Gurley, K. Bridget Brosnihan · 2011 · Hypertension
Angiotensin-(1-7) potentiates the coronary vasodilatatory effect of bradykinin in the isolated rat heart
Alvair P. Almeida, B.C. Frábregas, Marcos Magalhães Madureira · 2000 · Brazilian Journal of Medical and Biological Research
Angiotensin‐(1–7) induces cerebral ischaemic tolerance by promoting brain angiogenesis in a M as/ eNOS ‐dependent pathway
Teng Jiang, Jin‐Tai Yu, Xi‐Chen Zhu, Qiao-Quan Zhang, Meng‐Shan Tan, Lei Cao, Hui-Fu Wang, Jie Lu, Qing Gao, Yingdong Zhang et al. · 2014 · British Journal of Pharmacology
Protective arms of the renin–angiotensin‐system in neurological disease
Colin Sumners, Masatsugu Horiuchi, Robert E. Widdop, Claudia A. McCarthy, Thomas Unger, U. Muscha Steckelings · 2013 · Clinical and Experimental Pharmacology and Physiology
Physiological genomic analysis of the brain renin-angiotensin system
Robin L. Davisson · 2003 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
The association of thirst, sodium appetite and vasopressin release with c-fos expression in the forebrain of the rat after intracerebroventricular injection of angiotensin II, angiotensin-(1–7) or carbachol
Julie M. Mahon, Matthew J. Allen, Joe Herbert · 1995 · Neuroscience
Angiotensin-Converting Enzyme 2 (ACE2) Activator Diminazene Aceturate Ameliorates Endotoxin-Induced Uveitis in Mice
Yiguo Qiu, Pollob Kumar Shil, Ping Zhu · 2014 · Investigative Ophthalmology & Visual Science
Oral administration of angiotensin-(1–7) ameliorates type 2 diabetes in rats
Sérgio Henrique Sousa Santos, Jorge Fernando Giani, Valeria Burghi, Johanna Gabriela Miquet, Fatimunnisa Qadri, Janaina F Braga, Mihail Todiraş, Katarina Kotnik, Natalia V. Alenina, Fernando Pablo Dominici et al. · 2013 · Journal of Molecular Medicine
Angiotensin-(1–7)/Mas axis integrity is required for the expression of object recognition memory
Thiago Luiz do Nascimento Lazaroni, Ana Cláudia S. Raslan, Walkíria Ramos Peliky Fontes, Marilene L. Oliveira, Michael Bäder, Natalia V. Alenina, Márcio Flávio Dutra Moraes, Robson A.S. Santos, Grace Schenatto Pereira · 2011 · Neurobiology of Learning and Memory
Angiotensin-(1-7) inhibits the migration and invasion of A549 human lung adenocarcinoma cells through inactivation of the PI3K/Akt and MAPK signaling pathways
Huanying Wan · 2011 · Oncology Reports
Lifetime Overproduction of Circulating Angiotensin-(1-7) Attenuates Deoxycorticosterone Acetate-Salt Hypertension-Induced Cardiac Dysfunction and Remodeling
Nivia M Santiago, Priscila S. Guimarães, Raquel A. Sirvente, Laser Antônio Machado Oliveira, Maria Cláudia Irigoyen, Robson A.S. Santos, Maria José Campagnole‐Santos · 2010 · Hypertension
Impaired Heart Rate Baroreflex in Older Rats
Atsushi Sakima, David B. Averill, Patricia E. Gallagher, Sherry Oden Kasper, Ellen N. Tommasi, Carlos Maria Ferrario, Debra I. Diz · 2005 · Hypertension
Angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas axis activates Akt signaling to ameliorate hepatic steatosis
Xi Cao, Fangyuan Yang, Tingting Shi, Mingxia Yuan, Xin Zhong, Rong-Rong Xie, Sen Li, Hongbing Li, Jin‐Kui Yang · 2016 · Scientific Reports
Modulation of the baroreflex control of heart rate by angiotensin-(1–7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats
Gláucia Z. Chaves, Sordaini Maria Caligiorne, Robson A.S. Santos · 2000 · Journal of Hypertension
Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2−/− mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation
Chao Fang, Evi X. Stavrou, Alec A. Schmaier, Nadja Grobe, Mariana Morris, Andrew Chen, Marvin T. Nieman, Gregory N. Adams, Gretchen A. Larusch, Yihua Zhou et al. · 2013 · Blood
Activation of the ACE2/Ang-(1–7)/Mas pathway reduces oxygen–glucose deprivation-induced tissue swelling, ROS production, and cell death in mouse brain with angiotensin II overproduction
Jian Zheng, G. Li, Shuzhen Chen, Ji Chen Bihl, J. Buck, Yulan Zhu, H. Xia, Eric D. Lazartigues, Y. Chen, James E. Olson · 2014 · Neuroscience
Angiotensin-(1-7) improves the post-ischemic function in isolated perfused rat hearts
Anderson Jose Ferreira, Robson A.S. Santos, Alvair P. Almeida · 2002 · Brazilian Journal of Medical and Biological Research
Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells
Elisandra Gava, A. Samad-Zadeh, Joe Zimpelmann, Nasim Bahramifarid, Gregory Thomas Kitten, Robson A.S. Santos, Rhian M. Touyz, Kevin D. Burns · 2009 · Nephrology Dialysis Transplantation
Angiotensin-(1–7) decreases skeletal muscle atrophy induced by angiotensin II through a Mas receptor-dependent mechanism
Cisternas, Franco, Morales, María Gabriela, Meneses, Carla, Simon, Felipe, Brandan, Enrique, Abrigo, Johanna, Vazquez, Yaneisi, Cabello-Verrugio, Claudio · 2015 · Clinical Science
Pathways of angiotensin‐(1–7) metabolism in the kidney
Mark C. Chappell, Alicia Jones Allred, Carlos Maria Ferrario · 2001 · Nephrology Dialysis Transplantation
Angiotensin-(1–7) activates growth-stimulatory pathways in human mesangial cells
Joseph Zimpelmann, Kevin D. Burns · 2008 · American Journal of Physiology-Renal Physiology
Beneficial Effects on Skeletal Muscle of the Angiotensin II Type 1 Receptor Blocker Irbesartan in Experimental Heart Failure
Luciano Dalla Libera, Barbara Ravara, Annalisa Angelini · 2001 · Circulation
Mas receptor mediates cardioprotection of angiotensin‐(1‐7) against Angiotensin II‐induced cardiomyocyte autophagy and cardiac remodelling through inhibition of oxidative stress
Li Lin, Xuebo Liu, Jianfeng Xu, Liqing Weng, Jun Tao Ren, Junbo Ge, Yunzeng Zou · 2015 · Journal of Cellular and Molecular Medicine
Angiotensin(1–7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H 2 O 2 -activated NLRP3 inflammasome/IL-1β/Smad circuit
Lili Zhang, Shan Huang, Xiaoxin Ma, Wenyong Zhang, Dan Wang, Siyi Jin, Yanping Zhang, Yang Li, Xu Li · 2016 · Free Radical Biology and Medicine
AVE 0991, a non‐peptide mimic of angiotensin‐(1–7) effects, attenuates pulmonary remodelling in a model of chronic asthma
Maria da Glória Rodrigues‐Machado, Giselle Santos Magalhães, J A Cardoso, Lucas Miranda Kangussu, A Murari, Marcelo Vidigal Caliari, Marilene L. Oliveira, Denise Carmona Cara, M L M Noviello, Fúlvia D. Marques et al. · 2013 · British Journal of Pharmacology
The renin–angiotensin system: peptides and enzymes beyond angiotensin II
Timothy L. Reudelhuber · 2005 · Current Opinion in Nephrology & Hypertension
Endothelial dysfunction through genetic deletion or inhibition of the G protein-coupled receptor Mas: a new target to improve endothelial function
Concepción Peiró, Susana Vallejo, Florian Gembardt · 2007 · Journal of Hypertension
Circulating Rather Than Cardiac Angiotensin-(1-7) Stimulates Cardioprotection After Myocardial Infarction
Yong Wang, Cheng Qian, Anton J.M. Roks, Dirk Westermann, Sarah-Mai Schumacher, Felicitas Escher, Regien G. Schoemaker, Timothy L. Reudelhuber, Wiek H. van Gilst, Heinz‐Peter Schultheiß et al. · 2010 · Circulation Heart Failure
A new strategy for treating hypertension by blocking the activity of the brain renin–angiotensin system with aminopeptidase A inhibitors
Ji Gao, Yannick Marc, Xavier Iturrioz, Vincent Leroux, Fabrice Balavoine, Catherine Llorens‐Cortés · 2014 · Clinical Science
Angiotensin-(1–7) attenuates diabetic nephropathy in Zucker diabetic fatty rats
Jorge Fernando Giani, Valeria Burghi, Luciana Cecilia Veiras, Analía Lorena Tomat, Marina Cecilia Muñoz, Gabriel Cao, Daniel Turyn, Jorge Eduardo Toblli, Fernando Pablo Dominici · 2012 · American Journal of Physiology-Renal Physiology
Effects of angiotensin II and angiotensin-(1-7) on the release of [3H]norepinephrine from rat atria.
Mariela Mercedes Gironacci, Edda Adler‐Graschinsky, C. Peña · 1994 · Hypertension
Immunohistochemical localization of the angiotensin-(1–7) receptor Mas in the murine forebrain
M. Freund, Thomas Walther, Oliver von Bohlen und Halbach · 2012 · Cell and Tissue Research
Infusion of angiotensin-(1–7) reduces glomerulosclerosis through counteracting angiotensin II in experimental glomerulonephritis
Jiandong Zhang, Nancy A. Noble, Wayne A. Border, Yufeng Huang · 2009 · American Journal of Physiology-Renal Physiology
Angiotensin II-induced pro-fibrotic effects require p38MAPK activity and transforming growth factor beta 1 expression in skeletal muscle cells
María Gabriela Morales, Yaneisi Vázquez, María José Acuña, Juan Carlos Aristizábal Rivera, Felipe Simón, José Diego Salas, Joel Álvarez‐Ruf, Enrique Brandan, Claudio Cabello‐Verrugio · 2012 · The International Journal of Biochemistry & Cell Biology
Use of a Biological Peptide Pump to Study Chronic Peptide Hormone Action in Transgenic Mice
Jorge P. van Kats, Danielle Méthot, Pierre Paradis · 2001 · Journal of Biological Chemistry
Interactions Between Angiotensin-(1-7), Kinins, and Angiotensin II in Kidney and Blood Vessels
Robson A.S. Santos, Kátia Tomagnini Passaglio, João Bosco Pesquero · 2001 · Hypertension
Autoradiographic localization of mas proto-oncogene mRNA in adult rat brain using in situ hybridization
Bernd Bunnemann, Kjell Fuxé, Rainer Metzger, John J. Mullins, Trevor Jackson, Michael R. Hanley, Detlev Ganten · 1990 · Neuroscience Letters
Cardiovascular effects produced by micro-injection of angiotensin-(1–7) on vasopressor and vasodepressor sites of the ventrolateral medulla
L.C.S. Silva, Marco Antônio Peliky Fontes, Maria José Campagnole‐Santos · 1993 · Brain Research
Central administration of angiotensin-(1–7) stimulates nitric oxide release and upregulates the endothelial nitric oxide synthase expression following focal cerebral ischemia/reperfusion in rats
Yingdong Zhang, Jie Lu, Jingping Shi, Xingjian Lin, Jingde Dong, Shugang Zhang, Yan Liu, Qiang Tong · 2008 · Neuropeptides
Angiotensin-(1–7) causes endothelium-dependent relaxation in canine middle cerebral artery
Kristian Feterik, Leslie Smith, Zvonimir S. Katušić · 2000 · Brain Research
Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy via the Mas receptor
Morales, María Gabriela, Abrigo, Johanna, Acuña, María José, Santos, Robson A., Bader, Michael, Brandan, Enrique, Simon, Felipe, Olguin, Hugo, Cabrera, Daniel, Cabello-Verrugio, Claudio · 2016 · Disease Models & Mechanisms
Genetic Deletion of ACE2 Induces Vascular Dysfunction in C57BL/6 Mice: Role of Nitric Oxide Imbalance and Oxidative Stress
Luíza Antas Rabelo, Mihail Todiraş, Valéria Nunes-Souza, Fatimunnisa Qadri, István András Szijártó, Maik Gollasch, Josef Martin Penninger, Michael Bäder, Robson A.S. Santos, Natalia V. Alenina · 2016 · PLoS ONE
Angiotensin-(1–7) stimulates water transport in rat inner medullary collecting duct: evidence for involvement of vasopressin V2 receptors
Antônio J. Magaldi, Kátia R. César, Magali de Araújo · 2003 · Pflügers Archiv - European Journal of Physiology
Oral administration of an angiotensin-converting enzyme 2 activator ameliorates diabetes-induced cardiac dysfunction
Tatiane Moisés Murça, Patrícia L. Moraes, C.A. Capuruço, Sérgio Henrique Sousa Santos, Marcos Barrouin Melo, Robson A.S. Santos, Vinayak Shenoy, Michael J. Katovich, Mohan K. Raizada, Anderson José Ferreira · 2012 · Regulatory Peptides
Estrogen regulation of the brain renin-angiotensin system in protection against angiotensin II-induced sensitization of hypertension
Baojian Xue, Zhongming Zhang, Terry G. Beltz, Fang Guo, Meredith Hay, Alan Kim Johnson · 2014 · American Journal of Physiology-Heart and Circulatory Physiology
Evidence that angiotensin‐(1–7) is an intermediate of gonadotrophin‐induced oocyte maturation in the rat preovulatory follicle
Honorato‐Sampaio, Kinulpe, Pereira, Virginia M., Santos, Robson A. S., Reis, Adelina M. · 2012 · Experimental Physiology
Injections of angiotensin‐converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats
Debra I. Diz, Maria Antonia Garcia-Espinosa, Stephen Gegick, Ellen N. Tommasi, Carlos Maria Ferrario, Elisabeth Ann Tallant, Mark C. Chappell, Patricia E. Gallagher · 2008 · Experimental Physiology
The ACE2/Ang-(1–7)/Mas axis can inhibit hepatic insulin resistance
Xi Cao, Fangyuan Yang, Xin Zhong, Rong-Rong Xie, Jin-Kui Yang · 2014 · Molecular and Cellular Endocrinology
Angiotensin-(1-7) Induces Bradykinin-Mediated Hypotensive Responses in Anesthetized Rats
Asad Abbas, Gabriela J. Gorelik, Luis A. Carbini · 1997 · Hypertension
Reduced plasma levels of angiotensin-(1-7) and renin activity in preeclamptic patients are associated with the angiotensin I- converting enzyme deletion/deletion genotype
Elizabeth Portugal Pimenta Velloso, Renata Lúcia Pereira Vieira, Antônio Carlos Vieira Cabral, Evanguedes Kalapothakis, Robson A.S. Santos · 2007 · Brazilian Journal of Medical and Biological Research
Angiotensin-(1–7): A Novel Peptide in the Ovary
Amilton Paulo Raposo Costa, Christiane R. Fagundes-Moura, Virgínia Mara Pereira, Leonardo F. Silva, Maria Aparecida Ribeiro Vieira, Robson A.S. Santos, Adelina Martha dos Reis · 2003 · Endocrinology
Angiotensin 1-7 as Means to Prevent the Metabolic Syndrome
Yonit Marcus, Gabi Shefer, Keren Sasson, Förtüne Kohen, Rona Limor, Orit Pappo, Nava Nevo, Inbal Eti Biton, Michal Yacobi Bach, Tamara Berkutzki et al. · 2012 · Diabetes
Time-Resolved Quantitative Phosphoproteomics: New Insights into Angiotensin-(1–7) Signaling Networks in Human Endothelial Cells
Thiago Verano‐Braga, Veit Schwämmle, Marc Sylvester · 2012 · Journal of Proteome Research
Chronic angiotensin (17) injection accelerates STZ-induced diabetic renal injury1
Ying Shao, Ming He, Li ZHOU, Tai Yao, Yü Huang, Limin Lü · 2008 · Acta Pharmacologica Sinica
Selective increase of angiotensin(1–7) and its receptor in hearts of spontaneously hypertensive rats subjected to physical training
Ary Gomes Filho, Anderson Jose Ferreira, Sérgio Henrique Sousa Santos · 2008 · Experimental Physiology
Brain endo-oligopeptidase B: a post-proline cleaving enzyme that inactivates angiotensin I and II.
Lewis Joel Greene, Augusto César Cropanese Spadaro, Antonio Roberto Martins, W D P Jesus, Antônio Carlos Martins de Camargo · 1982 · Hypertension
Antiglaucomatous Effects of the Activation of Intrinsic Angiotensin-Converting Enzyme 2
Giselle Foureaux, José Carlos Nogueira, B. S. Nogueira et al. · 2013 · Investigative Ophthalmology & Visual Science
Deletion of angiotensin-converting enzyme 2 promotes the development of atherosclerosis and arterial neointima formation
Sahara, Makoto, Ikutomi, Masayasu, Morita, Toshihiro, Minami, Yoshiyasu, Nakajima, Toshiaki, Hirata, Yasunobu, Nagai, Ryozo, Sata, Masataka · 2014 · Cardiovascular Research
Angiotensin-(1–7) infusion is associated with increased blood pressure and adverse cardiac remodelling in rats with subtotal nephrectomy
Elena Velkoska, Rachael G. Dean, Karen Griggs, Luke James Burchill, Louise M. Burrell · 2010 · Clinical Science
Role of ACE2 in diastolic and systolic heart failure
Wang Wang, Sreedhar Bodiga, Subhash K. Das, Jennifer Lo, Vaibhav B. Patel, Gavin Y. Oudit · 2011 · Heart Failure Reviews
Ablation of angiotensin (1-7) receptor Mas in C57Bl/6 mice causes endothelial dysfunction
Luíza Antas Rabelo, Ping Xu, Mihail Todiraş · 2008 · Journal of the American Society of Hypertension
Angiotensin-(1–7) reduces proteinuria and diminishes structural damage in renal tissue of stroke-prone spontaneously hypertensive rats
Jorge Fernando Giani, Marina Cecilia Muñoz, Romina A. Pons · 2010 · American Journal of Physiology-Renal Physiology
Angiotensin-(1-7): a novel vasodilator of the coronary circulation.
K. Bridget Brosnihan, P Li, Elisabeth Ann Tallant · 1998 · PubMed
Angiotensin(1–7) potentiates bradykinin-induced vasodilatation in man
Shinichiro Ueda, Satoko Masumori‐Maemoto, Atsushi Wada, Masao Ishii, K. Bridget Brosnihan, Satoshi Umemura · 2001 · Journal of Hypertension
Involvement of the Gi/o/cGMP/PKG pathway in the AT2-mediated inhibition of outer cortex proximal tubule Na+-ATPase by Ang-(1–7)
Lucienne S. Lara, Fabíola Cavalcante, Flavia Axelband, Aloa Machado De Souza, Aníbal Gil Lopes, Celso Caruso‐Neves · 2006 · Biochemical Journal
Beneficial Effects of the Activation of the Angiotensin-(1–7) Mas Receptor in a Murine Model of Adriamycin-Induced Nephropathy
Kátia Daniela da Silveira, Lívia Corrêa Barroso, Angelica Thomas Vieira, Daniel Cisalpino, Cristiano Xavier Lima, Michael Bäder, Rosa Maria Esteves Arantes, Robson A.S. Santos, Ana Cristina Simões e Silva, Mauro Martins Teixeira · 2013 · PLoS ONE
Angiotensin-(1–7) binding at angiotensin II receptors in the rat brain
Brian P. Rowe, David L. Saylor, Robert Charles Speth, Dale R. Absher · 1995 · Regulatory Peptides
Angiotensin-(1–7) improves cardiac remodeling and inhibits growth-promoting pathways in the heart of fructose-fed rats
Jorge Fernando Giani, Marina Cecilia Muñoz, Marcos Alejandro Mayer, Luciana Cecilia Veiras, Cristina Teresa Arranz, Carlos Alberto Taira, Daniel Turyn, Jorge Eduardo Toblli, Fernando Pablo Dominici · 2010 · American Journal of Physiology-Heart and Circulatory Physiology
Association Between the Natriuretic Action of Angiotensin-(1-7) and Selective Stimulation of Renal Prostaglandin I2Release
Sean D. Hilchey, Caroline P. Bell‐Quilley · 1995 · Hypertension
Angiotensin‐converting enzyme 2 gene targeting studies in mice: mixed messages
Susan B. Gurley, Thomas M. Coffman · 2008 · Experimental Physiology
Angiotensin-(1-7) stimulates the phosphorylation of Akt in rat extracardiac tissues in vivo via receptor Mas
Marina Cecilia Muñoz, Jorge Fernando Giani, Fernando Pablo Dominici · 2010 · Regulatory Peptides
Effects of Angiotensin-(1-7) on Forearm Circulation in Normotensive Subjects and Patients With Essential Hypertension
Shota Sasaki, Yukihito Higashi, Keigo Nakagawa, Hideo Matsuura, Goro Kajiyama, Tetsuya Oshima · 2001 · Hypertension
Angiotensin-(1–7) central administration induces anxiolytic-like effects in elevated plus maze and decreased oxidative stress in the amygdala
Walther Bild, Alin Stelian Ciobica · 2012 · Journal of Affective Disorders
Expression of an angiotensin-(1-7)-producing fusion protein in rats induced marked changes in regional vascular resistance
Giancarla Aparecida Botelho Santos, Walkyria Oliveira Sampaio, Timothy L. Reudelhuber, Michael Bäder, Maria José Campagnole‐Santos, Robson A.S. Santos · 2007 · American Journal of Physiology-Heart and Circulatory Physiology
Angiotensin-(1–7) in the Rostral Ventrolateral Medulla Modulates Enhanced Cardiac Sympathetic Afferent Reflex and Sympathetic Activation in Renovascular Hypertensive Rats
Peng Li, Hai‐Jian Sun, Baiping Cui, Ye‐Bo Zhou, Ying Han · 2013 · Hypertension
ACE2 deficiency reduces β-cell mass and impairs β-cell proliferation in obese C57BL/6 mice
Robin Shoemaker, Frederique B. Yiannikouris, Sean Eric Thatcher, Lisa Ann Cassis · 2015 · American Journal of Physiology-Endocrinology and Metabolism
Angiotensin-(1–7) attenuates angiotensin II-induced cardiac hypertrophy via a Sirt3-dependent mechanism
Lirong Guo, Ankang Yin, Qi Zhang, Tiecheng Zhong, Stephen T. O’Rourke, Chengwen Sun · 2017 · American Journal of Physiology-Heart and Circulatory Physiology
Effects of angiotensin analogues and angiotensin receptor antagonists on paraventricular neurones
Philipp Ambühl, Dominik Felix, Hans Imboden · 1992 · Regulatory Peptides
Angiotensin-(1-7) attenuates the anxiety and depression-like behaviors in transgenic rats with low brain angiotensinogen
Lucas Miranda Kangussu, Ana Flávia Almeida-Santos, Michael Bäder, Natalia V. Alenina, Marco Antônio Peliky Fontes, Robson A.S. Santos, Daniele Cristina de Aguiar, Maria José Campagnole‐Santos · 2013 · Behavioural Brain Research
ACE2 deficiency increases NADPH-mediated oxidative stress in the kidney
Jan A Wysocki, David I. Ortiz-Melo, Natalie K Mattocks, Katherine H. Xu, Jessica Prescott, Karla Evora, Minghao Ye, Matthew A. Sparks, Syed K. Haque, DANIEL C. BATLLE et al. · 2014 · Physiological Reports
Newly Discovered Components and Actions of the Renin–Angiotensin System
Robert M. Carey · 2013 · Hypertension
Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology
Yanfei Qi, Vinayak Shenoy, Fong Wong, Hongwei Li, Aqeela Afzal, J Mocco, Colin Sumners, Mohan K. Raizada, Michael J. Katovich · 2011 · Experimental Physiology
Centrally administered angiotensin‐(1–7) increases the survival of stroke‐prone spontaneously hypertensive rats
Robert William Regenhardt, Adam P. Mecca, Fiona A. Desland, Phillip F. Ritucci‐Chinni, Jacob A. Ludin, David Greenstein, Cristina Bañuelos, Jennifer L. Bizon, Mary K. Reinhard, Colin Sumners · 2013 · Experimental Physiology
The Mas receptor mediates modulation of insulin signaling by angiotensin-(1–7)
Marina Cecilia Muñoz, Jorge Fernando Giani, Valeria Burghi, Marcos Alejandro Mayer, Andrea Carranza, Carlos Alberto Taira, Fernando Pablo Dominici · 2012 · Regulatory Peptides
[7-D-ALA]-angiotensin-(1–7): Selective antagonism of angiotensin-(1–7) in the rat paraventricular nucleus
Philipp Ambühl, Dominik Felix, Mahesh C. Khosla · 1994 · Brain Research Bulletin
Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury
Qiuhua Chen, Yi Yang, Yingzi Huang, Chun Shui Pan, Ling Liu, Haibo Qiu · 2013 · Journal of Surgical Research
Intrapulmonary Activation of the Angiotensin-Converting Enzyme Type 2/Angiotensin 1-7/G-Protein-Coupled Mas Receptor Axis Attenuates Pulmonary Hypertension in Ren-2 Transgenic Rats Exposed to Chronic Hypoxia
Václav Hampl, Jan Herget, Jana Bı́bová, Alena Baňasová, Zuzana Husková, Z. Vaňourková, Šárka Jíchová, Petr Kujal, Zdeňka Vernerová, Janusz Sadowski et al. · 2015 · Physiological Research
The Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas receptor axis: A potential target for treating thrombotic diseases
Rodrigo A. Fraga‐Silva, Danielle Da Silva, Fabrizio Montecucco, François Mach, Nikolaos Stergiopulos, Rafaela da Silva, Robson A.S. Santos · 2012 · Thrombosis and Haemostasis
Chronic infusion of angiotensin-(1-7) into the lateral ventricle of the brain attenuates hypertension in DOCA-salt rats
Priscila S. Guimarães, Nivia M Santiago, Carlos Henrique Xavier, Elizabeth Portugal Pimenta Velloso, Marco Antônio Peliky Fontes, Robson A.S. Santos, Maria José Campagnole‐Santos · 2012 · American Journal of Physiology-Heart and Circulatory Physiology
Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats
Marco Antônio Peliky Fontes, Ovidiu Constantin Baltatu, Sordaini Maria Caligiorne · 2000 · Physiological Genomics
Renoprotective Effects of AVE0991, a Nonpeptide Mas Receptor Agonist, in Experimental Acute Renal Injury
Lívia Corrêa Barroso, Kátia Daniela da Silveira, Cristiano Xavier Lima, Valdinéria Oliveira Borges, Michael Bäder, Milene Alvarenga Rachid, Robson A.S. Santos, Danielle G. Souza, Ana Cristina Simões e Silva, Mauro Martins Teixeira · 2012 · International Journal of Hypertension
Beneficial Effects of Long‐Term Administration of an Oral Formulation of Angiotensin‐(1–7) in Infarcted Rats
Fúlvia D. Marques, Marcos Barrouin Melo, Leandro Eziquiel de Souza, Maria Cláudia Irigoyen, Rubén D. Sinisterra, Frederico B. De Sousa, Sílvia Q. Savergnini, Vinícius B. A. Braga, Anderson Jose Ferreira, Robson A.S. Santos · 2012 · International Journal of Hypertension
Angiotensin‐(1–7) through AT2receptors mediates tyrosine hydroxylase degradation via the ubiquitin–proteasome pathway
Marı́a A. Lopez Verrilli, Carlos Jose Pirola, Mariano M. Pascual, Fernando Pablo Dominici, Daniel Turyn, Mariela Mercedes Gironacci · 2009 · Journal of Neurochemistry
Effect of Angiotensin-(1-7) and Bradykinin in Patients With Heart Failure Treated With an ACE Inhibitor
Andrew P. Davie, John J.V. McMurray · 1999 · Hypertension
Central and peripheral actions of angiotensin-(1-7).
Robson A.S. Santos, Maria José Campagnole‐Santos · 1994 · PubMed
ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice
Kai Yan Mak, Ruth Antoinette D. Chin, Sharon C. Cunningham, Miriam R. Habib, Joseph Torresi, Alexandra F. Sharland, Ian E. Alexander, Peter Angus, Chandana B. Herath · 2015 · Molecular Therapy
Angiotensin-(1–7) counteracts the effects of Ang II on vascular smooth muscle cells, vascular remodeling and hemorrhagic stroke: Role of the NFкB inflammatory pathway
Ji Chen Bihl, Cheng Zhang, Yuhui Zhao, Xiang Xiao, Xiaotang Ma, Yusen Chen, Shuzhen Chen, Bin Zhao, Yusen Chen · 2015 · Vascular Pharmacology
Blockade of Endogenous Angiotensin-(1–7) in the Hypothalamic Paraventricular Nucleus Reduces Renal Sympathetic Tone
Ana Quênia Gomes da Silva, Robson A.S. Santos, Marco Antônio Peliky Fontes · 2005 · Hypertension
Protective axis of the renin–angiotensin system in the brain
Mariela Mercedes Gironacci, Flavia M. Cerniello, Nadia A. Longo Carbajosa, Jorge Goldstein, Bruno D. Cerrato · 2014 · Clinical Science
An orally active angiotensin-(1–7) inclusion compound and exercise training produce similar cardiovascular effects in spontaneously hypertensive rats
Mariane Bertagnolli, Karina Rabello Casali, Frederico B. De Sousa, Katya Rigatto, Lenice Kappes Becker, Sérgio Henrique Sousa Santos, Lucinara Dadda Dias, Graziela Hünning Pinto, Daniela Ravizzoni Dartora, Beatriz D'Agord Schaan et al. · 2013 · Peptides
Evidence that the vasodilator angiotensin-(1–7)-Mas axis plays an important role in erectile function
Andrey C. da Costa Gonçalves, Rômulo Leite, Rodrigo A. Fraga-Silva, Sérgio Veloso Brant Pinheiro, Augusto Barbosa Reis, Fernando Marcos dos Reis, Rhian M. Touyz, Robert Clinton Webb, Natalia V. Alenina, Michael Bäder et al. · 2007 · American Journal of Physiology-Heart and Circulatory Physiology
Targeting the ACE2–Ang-(1–7) pathway in cardiac fibroblasts to treat cardiac remodeling and heart failure
Michikado Iwata, Randy T. Cowling, Seon Ju Yeo, Barry Greenberg · 2010 · Journal of Molecular and Cellular Cardiology
Neurophysiological responses to angiotensin-(1-7).
D. Felix, M. C. Khosla, Karen L. Barnes, Hans Imboden, B Montani, Carlos Maria Ferrario · 1991 · Hypertension
Activation of the Neuroprotective Angiotensin-Converting Enzyme 2 in Rat Ischemic Stroke
Douglas M. Bennion, Emily Haltigan, Alexander Irwin, Lauren L. Donnangelo, Robert William Regenhardt, David J. Pioquinto, Daniel Lee Purich, Colin Sumners · 2015 · Hypertension
Isoproterenol-induced impairment of heart function and remodeling are attenuated by the nonpeptide angiotensin-(1-7) analogue AVE 0991
Anderson Jose Ferreira, Thauana Luiza de Oliveira, M. Castro · 2007 · Life Sciences
The expression of angiotensin-converting enzyme 2–angiotensin-(1–7)–Mas receptor axis are upregulated after acute cerebral ischemic stroke in rats
Jie Lu, Teng Jiang, Liang Wu, Li Gao, Yao Wang, Feng Zhou, Shugang Zhang, Yingdong Zhang · 2013 · Neuropeptides
Angiotensin (1-7) re-establishes impulse conduction in cardiac muscle during ischaemia-reperfusion. The role of the sodium pump
Walmor C. De Mello · 2004 · Journal of the Renin-Angiotensin-Aldosterone System
Effects of angiotensin-(1-7) and other bioactive components of the renin–angiotensin system on vascular resistance and noradrenaline release in rat kidney
Johannes Stegbauer, Oliver Vonend, Vitus Oberhauser · 2003 · Journal of Hypertension
Endotoxin-induced skeletal muscle wasting is prevented by angiotensin-(1–7) through a p38 MAPK-dependent mechanism
Morales, María Gabriela, Olguín, Hugo, Di Capua, Gabriella, Brandan, Enrique, Simon, Felipe, Cabello-Verrugio, Claudio · 2015 · Clinical Science
Angiotensin Converting Enzyme 2/Ang‐(1–7)/Mas Axis Protects Brain from Ischemic Injury with a Tendency of Age‐dependence
Jiaolin Zheng, Guang‐Ze Li, Shu‐Zhen Chen, Jinju Wang, James E. Olson, Huijing Xia, Eric D. Lazartigues, Yulan Zhu, Yanfang Chen · 2014 · CNS Neuroscience & Therapeutics
The angiotensin-(1–7)/Mas axis reduces myonuclear apoptosis during recovery from angiotensin II-induced skeletal muscle atrophy in mice
Carla Meneses, María Gabriela Morales, Johanna Ábrigo, Felipe Simón, Enrique Brandan, Claudio Cabello‐Verrugio · 2014 · Pflügers Archiv - European Journal of Physiology
The renin-angiotensin system during acute myocardial ischemia in dogs.
Robson A.S. Santos, José M. Brum, K. Bridget Brosnihan, Carlos Maria Ferrario · 1990 · Hypertension
Brain-Selective Overexpression of Angiotensin-Converting Enzyme 2 Attenuates Sympathetic Nerve Activity and Enhances Baroreflex Function in Chronic Heart Failure
Liang Xiao, Lie Gao, Eric D. Lazartigues, Irving H. Zucker · 2011 · Hypertension
Angiotensin-(1–7) upregulates cardiac nitric oxide synthase in spontaneously hypertensive rats
María A. Costa, Marı́a A. Lopez Verrilli, Karina A. Gómez, Pablo Nakagawa, Clara Peña, Cristina Teresa Arranz, Mariela Mercedes Gironacci · 2010 · American Journal of Physiology-Heart and Circulatory Physiology
Angiotensin-(1–7) prevents diabetes-induced attenuation in PPAR-γ and catalase activities
Gursev S. Dhaunsi, Mariam H.M. Yousif, Saghir Akhtar, Mark C. Chappell, Debra I. Diz, Ibrahim F. Benter · 2010 · European Journal of Pharmacology
The mas oncogene enhances angiotensin-induced [Ca2+]i responses in cells with pre-existing angiotensin II receptors
Clara Ambroz, Adrian J. L. Clark, Kevin J. Catt · 1991 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
The role of angiotensin‐(1–7) receptor Mas in spermatogenesis in mice and rats
Marcelo C. Leal, Sérgio Veloso Brant Pinheiro, Anderson Jose Ferreira, Robson A.S. Santos, Leonardo Santos Bordoni, Natalia V. Alenina, Michael Bäder, Luiz R. França · 2009 · Journal of Anatomy
The angiotensin-(1–7) receptor agonist AVE0991 is cardioprotective in diabetic rats
Linda Ebermann, Frank Spillmann, Melanie Sidiropoulos, Felicitas Escher, Silvia Heringer‐Walther, Heinz‐Peter Schultheiß, Carsten Tschöpe, Thomas Walther · 2008 · European Journal of Pharmacology
Effect of angiotensin-(1-7) on reperfusion arrhythmias in isolated rat hearts
Liomar A. A. Neves, Alvair P. Almeida, M. C. Khosla · 1997 · Brazilian Journal of Medical and Biological Research
Angiotensin-(1–7)-induced activation of ERK1/2 is cAMP/protein kinase A-dependent in glomerular mesangial cells
George C. Liu, Gavin Y. Oudit, Fei Fang · 2011 · American Journal of Physiology-Renal Physiology
Angiotensin-(1-7) Attenuates Kidney Injury Due to Obstructive Nephropathy in Rats
Chang Seong Kim, In Jin Kim, Eun Hui Bae · 2015 · PLoS ONE
ACE2 Is Augmented in Dystrophic Skeletal Muscle and Plays a Role in Decreasing Associated Fibrosis
Cecilia A Riquelme, María José Acuña, Javiera Torrejón, Daniela L. Rebolledo, Daniel Cabrera, Robson A.S. Santos, Enrique Brandan · 2014 · PLoS ONE
Impairment of the angiotensin-converting enzyme 2–angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension
Marcela Bürgelová, Zdeňka Vaňourková, Monika Thumová, Pavel Dvořák, Martin Opočenský, Herbert J. Kramer, Michal Želízko, Jan Malý, Michael Bäder, Luděk Červenka · 2009 · Journal of Hypertension
Baroreflex Improvement in SHR After ACE Inhibition Involves Angiotensin-(1-7)
Silvia Heringer‐Walther, Érica N. Batista, Thomas Walther · 2001 · Hypertension
Effects of ACE2 deficiency on physical performance and physiological adaptations of cardiac and skeletal muscle to exercise
Daisy Motta‐Santos, Robson A.S. Santos, Marilene L. Oliveira, Fatimunnisa Qadri, Marko Poglitsch, Valentina Mosienko, Lenice Kappes Becker, Maria José Campagnole‐Santos, Josef Martin Penninger, Natalia V. Alenina et al. · 2016 · Hypertension Research
Angiotensin 1–7: A peptide for preventing and treating metabolic syndrome
Sérgio Henrique Sousa Santos, João Marcus Oliveira Andrade · 2014 · Peptides
Adenoviral Delivery of Angiotensin-(1-7) or Angiotensin-(1-9) Inhibits Cardiomyocyte Hypertrophy via the Mas or Angiotensin Type 2 Receptor
Mónica Flores‐Muñoz, Bruno M.D.C. Godinho, Abdulaziz Almalik, Stuart A. Nicklin · 2012 · PLoS ONE
The angiotensin-converting enzyme 2/angiotensin (1–7)/Mas axis protects the function of pancreatic β cells by improving the function of islet microvascular endothelial cells
Chunli Lu, YING WANG, Yuan Li, Yang Li, Xiaoya Li · 2014 · International Journal of Molecular Medicine
Effects of Angiotensin Metabolites in the Coronary Vascular Bed of the Spontaneously Hypertensive Rat
Els Moltzer, Anna V.A. Verkuil, Richard van Veghel · 2009 · Hypertension
Renin–angiotensin system inhibitors and fibrosis in chronic liver disease: a systematic review
Gaeun Kim, Ju‐Young Kim, Yoo Li Lim · 2016 · Hepatology International
Angiotensin-(1-7) is a potent antidiuretic peptide in rats.
Robson A.S. Santos, Nilo C.V. Baracho · 1992 · PubMed
Effect of Intrarenal Infusion of Angiotensin–(1–7) in the Dog
Joram Heller, Holly Kramer, Jaroslav Maly · 2000 · Kidney & Blood Pressure Research
Effects of genetic deletion of angiotensin-(1–7) receptor Mas on cardiac function during ischemia/reperfusion in the isolated perfused mouse heart
Carlos H. Castro, Robson A.S. Santos, Anderson Jose Ferreira, Michael Bäder, Natalia V. Alenina, Alvair P. Almeida · 2006 · Life Sciences
Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea
Ana Quênia Gomes da Silva, Marco Antônio Peliky Fontes, Nancy Lapp Kanagy · 2010 · Brain Research
Anti-hypertensive Effects of Diminazene Aceturate: An Angiotensin- Converting Enzyme 2 Activator in Rats
Marilda L.A. De Maria, Liliane Diniz de Araújo, Rodrigo A. Fraga-Silva, Letícia A.S. Pereira, Heder José Ribeiro, Gustavo Batista Menezes, Vinayak Shenoy, Mohan K. Raizada, Anderson Jose Ferreira · 2015 · Protein and Peptide Letters
Attenuation of isoproterenol-induced cardiac fibrosis in transgenic rats harboring an angiotensin-(1-7)-producing fusion protein in the heart
Anderson Jose Ferreira, Carlos H. Castro, Sílvia Guatimosim et al. · 2010 · Therapeutic Advances in Cardiovascular Disease
Ang-(1–7) exerts protective role in blood–brain barrier damage by the balance of TIMP-1/MMP-9
Ji-Tao Wu, Duo Zhao, Shuang Wu, Dan Wang · 2014 · European Journal of Pharmacology
Differential Virological and Immunological Outcome of Severe Acute Respiratory Syndrome Coronavirus Infection in Susceptible and Resistant Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2
Naoko Yoshikawa, Tomoki Yoshikawa, Terence E. Hill, Cheng Huang, Douglas M. Watts, Shinji Makino, Gregg N. Milligan, Teh‐Sheng Chan, Clarence J. Peters, Chien-Te Kent Tseng · 2009 · Journal of Virology
Differential actions of angiotensin II and angiotensin-(1-7) on transmitter release.
Debra I. Diz, Nancy T. Pirro · 1992 · Hypertension
Angiotensin‐(1–7) administration benefits cardiac, renal and progenitor cell function in db/db mice
Anna Papinska, Nicholas M. Mordwinkin, Christopher J. Meeks, Sachin Suresh Jadhav, Kathleen E. Rodgers · 2015 · British Journal of Pharmacology
Degeneration of Cone Photoreceptors Induced by Expression of the Mas1 Protooncogene
Xiaoping Xu, Alexander B. Quiambao, Luisa Roveri, Machelle T. Pardue, Jeffrey L. Marx, P. Röhlich, Neal S. Peachey, Muayyad R. Al‐Ubaidi · 2000 · Experimental Neurology
Chronic infusion of angiotensin-(1–7) reduces heart angiotensin II levels in rats
Ana Cristina R. Mendes, Anderson Jose Ferreira, Sérgio Veloso Brant Pinheiro, Robson A.S. Santos · 2004 · Regulatory Peptides
[7-D-ALA]-Angiotensin 1-7 Blocks Renal Actions of Angiotensin 1-7 in the Anesthetized Rat
Volker Vallon, Nils Heyne, Kerstin Richter · 1998 · Journal of Cardiovascular Pharmacology
Angiotensin-(1-7) and Baroreflex Function in Nucleus Tractus Solitarii of (mRen2)27 Transgenic Rats
Debra I. Diz, Maria Antonia Garcia-Espinosa, Patricia E. Gallagher, Detlev Ganten, Carlos Maria Ferrario, David B. Averill · 2008 · Journal of Cardiovascular Pharmacology
Angiotensin-(1–7) and nitric oxide synthase in the hypothalamo-neurohypophysial system
Jarosław Całka, Christine H. Block · 1993 · Brain Research Bulletin
Beneficial versus harmful effects of Angiotensin (1-7) on impulse propagation and cardiac arrhythmias in the failing heart
Walmor C. De Mello, Carlos Maria Ferrario, Jewell A. Jessup · 2007 · Journal of the Renin-Angiotensin-Aldosterone System
Angiotensin-(1-7) Reduces Norepinephrine Release Through a Nitric Oxide Mechanism in Rat Hypothalamus
Mariela Mercedes Gironacci, Marcelo Sergio Vatta, Martin Rodriguez–Fermepin, Belisario Enrique Fernández, Clara Peña · 2000 · Hypertension
Angiotensin-(1–7) and angiotension II in the rostral ventrolateral medulla modulate the cardiac sympathetic afferent reflex and sympathetic activity in rats
Limin Zhou, Zhen Shi, Juan Gao · 2010 · Pflügers Archiv - European Journal of Physiology
Angiotensin-(1–7) abrogates mitogen-stimulated proliferation of cardiac fibroblasts
LaTronya T. McCollum, Patricia E. Gallagher, Elisabeth Ann Tallant · 2012 · Peptides
Angiotensin‐(1‐7)‐Mediated Signaling in Cardiomyocytes
Enéas Ricardo de Morais Gomes, Robson A.S. Santos, Sílvia Guatimosim · 2012 · International Journal of Hypertension
The role of angiotensin(1–7) in renal vasculature of the rat
Els A. van der Wouden, Peter Ochodnický, Richard Pe van Dokkum · 2006 · Journal of Hypertension
Angiotensin-(1-7) Inhibits Angiotensin II–Induced Signal Transduction
Zhiming Zhu, Jian Zhong, Shanjun Zhu, Daoyan Liu, Markus van der Giet, Martin Tepel · 2002 · Journal of Cardiovascular Pharmacology
Angiotensin-(1–1) Suppresses Hepatocellular Carcinoma Growth and Angiogenesis via Complex Interactions of Angiotensin II Type 1 Receptor, Angiotensin II Type 2 Receptor and Mas Receptor
Yanping Liu, Bin Li, Ximing Wang, Guishuang Li, Rui Shang, Jianmin Yang, Jiali Wang, Meng Zhang, Yuguo Chen, Yun Zhang et al. · 2015 · Molecular Medicine
The Effect of the Thioether‐Bridged, Stabilized Angiotensin‐(1–7) Analogue Cyclic Ang‐(1–7) on Cardiac Remodeling and Endothelial Function in Rats with Myocardial Infarction
Matej Durik, Richard van Veghel, Anneke Kuipers, Rick Rink, Marijke Haas Jimoh Akanbi, Gert N. Moll, A.H. Jan Danser, Anton J.M. Roks · 2011 · International Journal of Hypertension
Effect of Intratubular Application of Angiotensin 1-7 on Nephron Function
Volker Vallon, Kerstin Richter, Nils Heyne · 1997 · Kidney & Blood Pressure Research
Activation of angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas axis attenuates the cardiac reactivity to acute emotional stress
Augusto Martins Lima, Carlos Henrique Xavier, Anderson Jose Ferreira · 2013 · American Journal of Physiology-Heart and Circulatory Physiology
Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice
Atsushi Shiota, Koichi I. Yamamoto, Mitsuru Ohishi, Yuji Tatara, Miyuki Ohnishi, Yoshihiro Maekawa, Yoshihiro Iwamoto, Masao Takeda, Hiromi Rakugi · 2010 · Hypertension Research
High sucrose intake in rats is associated with increased ACE2 and angiotensin-(1–7) levels in the adipose tissue
Michella Soares Coêlho, Karen Lucasechi Lopes, Raphael Ribeiro de Aquino Freitas et al. · 2010 · Regulatory Peptides
Modulation of the action of insulin by angiotensin-(1–7)
Fernando Pablo Dominici, Valeria Burghi, Marina Cecilia Muñoz, Jorge Fernando Giani · 2014 · Clinical Science
Angiotensin-(1–7) modulates the ouabain-insensitive Na+-ATPase activity from basolateral membrane of the proximal tubule
Celso Caruso‐Neves, Lucienne S. Lara, L.B.A. Rangel · 2000 · Biochimica et Biophysica Acta (BBA) - Biomembranes
Reduction of angiotensin A and alamandine vasoactivity in the rabbit model of atherogenesis: differential effects of alamandine and A ng(1‐7)
Belthrand Habiyakare, Hiba Alsaadon, Michael L. Mathai · 2014 · International Journal of Experimental Pathology
Early Training-Induced Reduction of Angiotensinogen in Autonomic Areas—The Main Effect of Exercise on Brain Renin-Angiotensin System in Hypertensive Rats
Laiali Jurdi El Chaar, Tatiana Pereira Alves, Álvaro Martins Batista, Lisete Compagno Michelini · 2015 · PLoS ONE
Immunohistochemical localization of angiotensin II in the mouse pancreas
Po Sing Leung, Hsiao Chang Chan, P.Y.D. Wong · 1998 · The Histochemical Journal
Angiotensin-(1–7) treatment mitigates right ventricular fibrosis as a distinctive feature of diabetic cardiomyopathy
Panpan Hao, Jianmin Yang, Mingxiang Zhang, Kai Zhang, Yuguo Chen, Cheng Zhang, Yun Zhang · 2015 · American Journal of Physiology-Heart and Circulatory Physiology
Angiotensin-(1-7) improves cognitive function in rats with chronic cerebral hypoperfusion
Wei Xie, Donglin Zhu, Li Ji, Minjie Tian, Chang Xu, Jingping Shi · 2014 · Brain Research