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Cited by 763

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Measurement of Intracellular Calcium

Takahashi, Akiyuki, Camacho, Patricia, Lechleiter, James D., Herman, Brian·1999·Physiological Reviews

Abstract

To a certain extent, all cellular, physiological, and pathological phenomena that occur in cells are accompanied by ionic changes. The development of techniques allowing the measurement of such ion activities has contributed substantially to our understanding of normal and abnormal cellular function. Digital video microscopy, confocal laser scanning microscopy, and more recently multiphoton microscopy have allowed the precise spatial analysis of intracellular ion activity at the subcellular level in addition to measurement of its concentration. It is well known that Ca 2+regulates numerous physiological cellular phenomena as a second messenger as well as triggering pathological events such as cell injury and death. A number of methods have been developed to measure intracellular Ca 2+. In this review, we summarize the advantages and pitfalls of a variety of Ca 2+indicators used in both optical and nonoptical techniques employed for measuring intracellular Ca 2+concentration.

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Crossref · 10.1152/physrev.1999.79.4.1089

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Metadata

Authors
Takahashi, A., Camacho, P., Lechleiter, J. D., & Herman, B.
Venue
Physiological Reviews
Published
1999-01-10
Volume
79
Issue
4
Pages
1089-1125
ISSN
  • 0031-9333 (ISSN-L)
  • 1522-1210
OpenAlex
W2154540873
Cited by
763
References
5
FWCI
2.02
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Measurement of Intracellular Calcium. https://app.cochat.ai/papers/10.1152/physrev.1999.79.4.1089
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Takahashi, A., Camacho, P., Lechleiter, J. D., & Herman, B. (1999). Measurement of Intracellular Calcium. Physiological Reviews. https://doi.org/10.1152/physrev.1999.79.4.1089

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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