The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Proteomic Patterns of Nipple Aspirate Fluids Obtained by SELDI‐TOF: Potential for New Biomarkers to Aid in the Diagnosis of Breast Cancer
Open accessAbstract
Nipple aspirate fluid (NAF) has been used for many years as a potential non‐invasive method to identify markers for breast cancer risk or early detection. Because individual markers have not been optimal, we are exploring the use of surface enhanced laser desorption and ionization time of flight (SELDI‐TOF) mass spectrometry to identify patterns of proteins that might define a proteomic signature for breast cancer. SELDI‐TOF was used to analyze a study set of NAF samples that included 12 women with breast cancer and 15 healthy controls (the latter included three women with an abnormal mammogram but subsequent normal biopsy). In this preliminary report, we present data showing that SELDI analysis of NAF is rapid, reproducible, and capable of identifying protein signatures that appear to differentiate NAF samples from breast cancer patients and healthy controls, including those with an abnormal mammogram who were later proven to be biopsy normal.
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Khan, J., Wei, J. S., Ringnér, M., Saal, L. H., Ladanyi, M., Westermann, F., Berthold, F., Schwab, M., Antonescu, C. R., Peterson, C., et al. (2001) · Nature Medicine · doi:10.1038/89044 · Cited by 2,644
Cited by
Li, J., Zhang, Z., Rosenzweig, J., Wang, Y. Y., & Chan, D. W. (2002) · Clinical Chemistry · doi:10.1093/clinchem/48.8.1296 · Cited by 893
Proteomic Characterization of the Interstitial Fluid Perfusing the Breast Tumor Microenvironment
Celis, J. E., Gromov, P., Cabezón, T., Moreira, J. M. A., Ambartsumian, N., Sandelin, K., Rank, F., & Gromova, I. (2004) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m400009-mcp200 · Cited by 305
The cancer cell secretome: A good source for discovering biomarkers?
Pavlou, M. P., & Diamandis, E. P. (2010) · Journal of Proteomics · doi:10.1016/j.jprot.2010.04.003 · Cited by 200
Proteomics in Clinical Trials and Practice
Azad, N. S., Rasool, N., Annunziata, C. M., Minasian, L., Whiteley, G., & Kohn, E. C. (2006) · Molecular & Cellular Proteomics · doi:10.1074/mcp.r600008-mcp200 · Cited by 85
Jézéquel, P., Campion, L., Spyratos, F., Loussouarn, D., Campone, M., Guérin‐Charbonnel, C., Joalland, M., André, J., Descotes, F., Grenot, C., et al. (2012) · International Journal of Cancer · doi:10.1002/ijc.26397 · Cited by 85
Metadata
- Authors
- Paweletz, C. P., Trock, B., Pennanen, M., Tsangaris, T., Magnant, C., Liotta, L. A., & Petricoin, E. F.
- Venue
- Disease Markers
- Publisher
- Wiley
- Published
- 2001-01
- Volume
- 17
- Issue
- 4
- Pages
- 301-307
- ISSN
- 0278-0240 (ISSN-L)
- 1875-8630
- OpenAlex
- W2102260352
- Cited by
- 285
- References
- 1
- FWCI
- 13.55
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Paweletz, C. P., Trock, B., Pennanen, M., Tsangaris, T., Magnant, C., Liotta, L. A., & Petricoin, E. F. (2001). Proteomic Patterns of Nipple Aspirate Fluids Obtained by SELDI‐TOF: Potential for New Biomarkers to Aid in the Diagnosis of Breast Cancer. Disease Markers. https://doi.org/10.1155/2001/674959
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