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Photodynamic Therapy for Cancer: Principles
Open accessAbstract
The principles of photodynamic therapy (PDT), using drugs (photosensitizers) that are activated by light to become cytotoxic, provide the basis for understanding the current and potential future clinical applications in gastroenterology, general oncology and other specialities. The properties of photosensitizers are key to their biological efficacy, while lasers and optical fibres allow convenient and flexible light delivery for endoscopic use. PDT has several distinct and unique advantages, both as a stand-alone treatment and in combination with other established modalities. The current limitations are also recognized, as is the need for rigorous randomized trials of this emerging technology. The fluorescence of many photosensitizers may be useful, either for (endoscopic) diagnosis or for PDT treatment guidance and monitoring.
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Cited by
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Polymeric micelles: authoritative aspects for drug delivery
Kulthe, S. S., Choudhari, Y. M., Inamdar, N. N., & Mourya, V. (2012) · Designed Monomers and Polymers · doi:10.1080/1385772x.2012.688328 · Cited by 235
Biswas, R., Chung, P.-S., Moon, J. H., Lee, S.-H., & Ahn, J.-C. (2014) · Lasers in Medical Science · doi:10.1007/s10103-013-1452-9 · Cited by 19
Potentiating effect of beta-glucans on photodynamic therapy of implanted cancer cells in mice
Akramiene, D., Aleksandraviciene, C., Grazeliene, G., Zalinkevicius, R., Suziedelis, K., Didziapetriene, J., Simonsen, U., Stankevicius, E., & Kevelaitis, E. (2010) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.220.299 · Cited by 17
Metadata
- Authors
- Wilson, B. C.
- Venue
- Canadian Journal of Gastroenterology
- Publisher
- Hindawi Limited
- Published
- 2002
- Volume
- 16
- Issue
- 6
- Pages
- 393-396
- ISSN
- 0835-7900 (ISSN-L)
- OpenAlex
- W143651898
- Cited by
- 232
- References
- 0
- FWCI
- 2.35
- Type
- journal article
- Language
- en
- Open access
- gold
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