The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Biomarkers for Lupus Nephritis: A Critical Appraisal
Open accessAbstract
Kidney disease is one of the most serious manifestations of systemic lupus erythematosus (SLE). Despite the improvement in the medical care of SLE in the past two decades, the prognosis of lupus nephritis remains unsatisfactory. Besides exploring more effective but less toxic treatment modalities that will further improve the remission rate, early detection and treatment of renal activity may spare patients from intensive immunosuppressive therapies and reduce renal damage. Conventional clinical parameters such as creatinine clearance, proteinuria, urine sediments, anti-dsDNA, and complement levels are not sensitive or specific enough for detecting ongoing disease activity in the lupus kidneys and early relapse of nephritis. Thus, novel biomarkers are necessary to enhance the diagnostic accuracy and sensitivity of lupus renal disease, prognostic stratification, monitoring of treatment response, and detection of early renal flares. This paper reviews promising biomarkers that have recently been evaluated in longitudinal studies of lupus nephritis.
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Mishra, J., Ma, Q., Prada, A., Mitsnefes, M., Zahedi, K., Yang, J., Barasch, J., & Devarajan, P. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000088027.54400.c6 · Cited by 1,749
Mok, C. C., Tang, S. S. K., To, C. H., & Petri, M. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21224 · Cited by 237
Self-citationUrinary neutrophil gelatinase-associated lipocalcin in D+HUS: a novel marker of renal injury
Investigators of the HUS-SYNSORB Pk Multicenter Clinical Trial, Trachtman, H., Christen, E., Cnaan, A., Patrick, J., Mai, V., Mishra, J., Jain, A., Bullington, N., & Devarajan, P. (2006) · Pediatric Nephrology · doi:10.1007/s00467-006-0146-y · Cited by 204
Biomarkers of lupus nephritis determined by serial urine proteomics
Zhang, X., Jin, M., Wu, H., Nadasdy, T., Nadasdy, G., Harris, N., Green-Church, K., Nagaraja, H., Birmingham, D. J., Yu, C.-Y., et al. (2008) · Kidney International · doi:10.1038/ki.2008.316 · Cited by 136
Manson, J. J., Ma, A., Rogers, P., Mason, L. J., Berden, J. H., van der Vlag, J., D'Cruz, D. P., Isenberg, D. A., & Rahman, A. (2009) · Arthritis Research & Therapy · doi:10.1186/ar2831 · Cited by 129
Cited by
Taming lupus-a new understanding of pathogenesis is leading to clinical advances
Liu, Z., & Davidson, A. (2012) · Nature Medicine · doi:10.1038/nm.2752 · Cited by 433
Interleukin-17 cytokines are critical in development of fatal lupus glomerulonephritis
Pisitkun, P., Ha, H.-L., Wang, H., Claudio, E., Tivy, C. C., Zhou, H., Mayadas, T. N., Illei, G. G., & Siebenlist, U. (2012) · Immunity · doi:10.1016/j.immuni.2012.08.014 · Cited by 174
Mummert, E., Fritzler, M. J., Sjöwall, C., Bentow, C., & Mahler, M. (2018) · Journal of Immunological Methods · doi:10.1016/j.jim.2018.05.014 · Cited by 86
Mok, C. C., Ho, L. Y., Leung, H. W., & Wong, L. G. (2010) · Translational research · doi:10.1016/j.trsl.2010.07.009 · Cited by 56
Metadata
- Authors
- Mok, C. C.
- Venue
- Journal of Biomedicine and Biotechnology
- Publisher
- Hindawi Limited
- Published
- 2010
- Volume
- 2010
- Pages
- 1-11
- ISSN
- 1110-7243 (ISSN-L)
- 1110-7251
- OpenAlex
- W1965790129
- Cited by
- 189
- References
- 5
- FWCI
- 7.03
- Type
- journal article
- Language
- en
- Open access
- hybrid
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