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Cited by 158

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Integrin Signaling, Cell Survival, and Anoikis: Distinctions, Differences, and Differentiation

Open access
Vachon, Pierre H.·2011·Journal of Signal Transduction

Abstract

Cell survival and apoptosis implicate an increasing complexity of players and signaling pathways which regulate not only the decision-making process of surviving (or dying), but as well the execution of cell death proper. The same complex nature applies to anoikis, a form of caspase-dependent apoptosis that is largely regulated by integrin-mediated, cell-extracellular matrix interactions. Not surprisingly, the regulation of cell survival, apoptosis, and anoikis furthermore implicates additional mechanistic distinctions according to the specific tissue, cell type, and species. Incidentally, studies in recent years have unearthed yet another layer of complexity in the regulation of these cell processes, namely, the implication of cell differentiation state-specific mechanisms. Further analyses of such differentiation state-distinct mechanisms, either under normal or physiopathological contexts, should increase our understanding of diseases which implicate a deregulation of integrin function, cell survival, and anoikis.

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Crossref · 10.1155/2011/738137

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Metadata

Authors
Vachon, P. H.
Venue
Journal of Signal Transduction
Publisher
Wiley
Published
2011-07-13
Volume
2011
Pages
1-18
ISSN
  • 2090-1739 (ISSN-L)
  • 2090-1747
OpenAlex
W2151476386
Cited by
158
References
18
FWCI
5.51
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Integrin Signaling, Cell Survival, and Anoikis: Distinctions, Differences, and Differentiation. https://app.cochat.ai/papers/10.1155/2011/738137
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Vachon, P. H. (2011). Integrin Signaling, Cell Survival, and Anoikis: Distinctions, Differences, and Differentiation. Journal of Signal Transduction. https://doi.org/10.1155/2011/738137

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.