The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.
Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery
Open accessAbstract
Lipids and lipid nanoparticles are extensively employed as oral-delivery systems for drugs and other active ingredients. These have been exploited for many features in the field of pharmaceutical technology. Lipids usually enhance drug absorption in the gastrointestinal tract (GIT), and when formulated as nanoparticles, these molecules improve mucosal adhesion due to small particle size and increasing their GIT residence time. In addition, lipid nanoparticles may also protect the loaded drugs from chemical and enzymatic degradation and gradually release drug molecules from the lipid matrix into blood, resulting in improved therapeutic profiles compared to free drug. Therefore, due to their physiological and biodegradable properties, lipid molecules may decrease adverse side effects and chronic toxicity of the drug-delivery systems when compared to other of polymeric nature. This paper highlights the importance of lipid nanoparticles to modify the release profile and the pharmacokinetic parameters of drugs when administrated through oral route.
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Cites
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Cited by
Tenchov, R., Bird, R., Curtze, A. E., & Zhou, Q. (2021) · ACS Nano · doi:10.1021/acsnano.1c04996 · Cited by 2,221
Skin cancer and new treatment perspectives: A review
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SLN and NLC for topical, dermal, and transdermal drug delivery
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Self-citationSridhar, A., Ponnuchamy, M., Kumar, P. S., & Kapoor, A. (2021) · Environmental Chemistry Letters · doi:10.1007/s10311-020-01126-2 · Cited by 299
Formulation and delivery of itraconazole to the brain using a nanolipid carrier system
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Metadata
- Authors
- Severino, P., Andreani, T., Macedo, A. S., Fangueiro, J. F., Santana, M. H. A., Silva, A. M., & Souto, E. B.
- Venue
- Journal of Drug Delivery
- Publisher
- Wiley
- Published
- 2012-11-24
- Volume
- 2012
- Pages
- 1-10
- ISSN
- 2090-3014 (ISSN-L)
- 2090-3022
- OpenAlex
- W2012179823
- Cited by
- 276
- References
- 101
- FWCI
- 5.57
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Severino, P., Andreani, T., Macedo, A. S., Fangueiro, J. F., Santana, M. H. A., Silva, A. M., & Souto, E. B. (2012). Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery. Journal of Drug Delivery. https://doi.org/10.1155/2012/750891
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
