The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats
Open accessAbstract
In this experiment, we established an animal model of gestational diabetes mellitus rats using streptozotocin. Using the rat model of GDM, the pregnant rats in 1-19d were divided into three groups: (1) Zuogui Wan gestational diabetes mellitus group (group I,n=12), (2) gestational diabetes mellitus rats as the control group (group II,n=11), and (3) rats of normal pregnancy group (group III,n=11). Compared with gestational diabetes mellitus rats as the control group, Zuogui Wan can change the indexes of fasting blood glucose, body weight, total cholesterol, insulin, and metabolism cage index significantly in Zuogui Wan gestational diabetes mellitus group. We can conclude that Zuogui Wan has the therapeutic effect on gestational diabetes mellitus.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In a streptozotocin-induced rodent model of GDM, Zuo Gui Wan treatment reduced fasting blood glucose, body weight, total cholesterol, and serum insulin level in mice fed a high fat and sugar diet.
“In a streptozotocin-induced rodent model of GDM, Zuo Gui Wan treatment reduced fasting blood glucose, body weight, total cholesterol, and serum insulin level of mice fed on high fat and sugar diet [22].”
From Evaluating Traditional Chinese Medicine and Herbal Products for the Treatment of Gestational Diabetes Mellitus (2019) · cites this paper as [22]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Maternal environment and the transgenerational cycle of obesity and diabetes.
Dabelea, D., & Crume, T. (2011) · Diabetes · doi:10.2337/db11-0400 · Cited by 347 · see citing works
Gestational diabetes mellitus: all Asians are not alike.
Chu, S. Y., Abe, K., Hall, L. R., Kim, S., Njoroge, T., & Qin, C. (2009) · Preventive Medicine · doi:10.1016/j.ypmed.2009.07.001 · Cited by 129 · see citing works
The Epidemiology of Diabetes in Pregnant Native Canadians: A risk profile
Harris, S. B., Caulfield, L. E., Sugamori, M. E., Whalen, E. A., & Henning, B. (1997) · Diabetes Care · doi:10.2337/diacare.20.9.1422 · Cited by 103 · see citing works
Developmental programming and diabetes – The human experience and insight from animal models
Poston, L. (2010) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2010.05.007 · Cited by 83 · see citing works
Fetal Determinants of Type 2 Diabetes
Reusens, B., Ozanne, S. E., & Remacle, C. (2007) · Current Drug Targets · doi:10.2174/138945007781386866 · Cited by 44 · see citing works
Serial Estimation of Urinary Fibrin/Fibrinogen Degradation Products in Kidney Transplantation
Hall, C. L., Pejhan, N., Thomson, R. W., et al. (1973) · BMJ · doi:10.1136/bmj.3.5873.204 · Cited by 9 · see citing works
[Effect of zuoguiwan on early embryonic development of mice].
Feng, Q. J., Feng, M. L., & Wang, Y. L. (1996) · PubMed · Cited by 3 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 9
- [3]Wei Y Yang H Gao X Analysis of the factors of diabetes and its influencing national survey of pregnancy Chinese Medical Association of Obstetrics and Gynecology 2007 2 Chinese Medical Association of the first session of the global Chinese Department of gynaecology and obstetrics and the third National Congress of Obstetrics and gynecology in young physician academic conference proceedings
- [7]Yang S Wen M Liang J Su W Intravenous injection of alloxan diabetic pregnancy four preparation of rat animal model Journal of Hainan Medical University 2006 2 118 120
- [8]Liu G Zhao L Liu H Kang J Experimental study on streptozotocin induced diabetes in pregnancy affect fetal development China Journal of Pediatrics 2008 1 26 30, 65
- [9]Wang X Li Y Su Z Zhao J The effect of Rehmannia glutinosa oligosaccharides on gestational diabetes mellitus rats blood glucose and insulin levels The British Medical Journal 2007 3 204 206
- [10]Qiu B Li R Effect of Ophiopogon japonicus polysaccharide on blood glucose in diabetic pregnant rats Journal of Jinan University (Medical Science Edition) 2008 4 367 369
- [14]Hao Z Hang B Wang Y Hypoglycemic effect of yam decoction on experimental mice Journal of China Medicine University 1991 3 158 160
- [19]Liu Y Cai D Chen X Shen Z Effect of Zuogui Wan on the thymus and lymphocyte proliferative response in MSG-rats Journal of Clinical Laboratory Science China 1998 4 3 5
- [21]Feng QJ Feng M Wang YL Yang YH Wu YP Kidney tonifying prescription Zuogui Wan (soup) influence on early embryonic development in mice Journal of Integrated Traditional Chinese and Western Medicine Chinese 1996 11 673 675 9772619
- [22]Xu K Wang Y Yang X Niu X Liu Y Feng Q Effect of tonifying kidney recipes on the generation of mice nonspecific immune function Journal of Clinical Laboratory Science China 2012 9 161 164
Cited by
Sorted by citations
Xu, Y. X. Z., Xi, S., & Qian, X. (2019) · Journal of Diabetes Research · doi:10.1155/2019/9182595 · Cited by 42 · see citing works
Wang, Y., Feng, Q., Niu, X., Xu, K., Wang, Y., Wang, J., Li, Q., Mao, Y., & Gao, S. (2016) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2016/9417362 · Cited by 16 · see citing works
Self-citationYI, L., Wei, C., & Fan, W. (2017) · Gynecological Endocrinology · doi:10.1080/09513590.2017.1318368 · Cited by 12 · see citing works
- Authors
- Wang, Y., Feng, Q., Niu, X., Liu, X., Xu, K., Yang, X., Wang, H., & Li, Q.
- Affiliations
- Beijing University of Chinese Medicine (CN)
- Shanxi University of Traditional Chinese Medicine (CN)
- Zhejiang University (CN)
- Corresponding author
- Feng, Qianjin
- Venue
- Journal of Analytical Methods in Chemistry
- Publisher
- Wiley
- Published
- 2014
- Volume
- 2014
- Pages
- 1-6
- ISSN
- 2090-8865 (ISSN-L)
- 2090-8873
- PMC
- PMC4129929
- OpenAlex
- W2090326184
- Cited by
- 20
- References
- 7
- Citations by year
- 2025: 3 · 2023: 1 · 2022: 2 · 2021: 3 · 2019: 3 · 2018: 1 · 2017: 4 · 2016: 3
- FWCI
- 1.88
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Journal of Analytical Methods in Chemistry (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Science and Technology Cooperation Projects (0102012DFA31330)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Complementary and alternative medicine › Medical Research and Treatments
- Keywords
- gestational diabetes mellitus, traditional Chinese medicine, streptozotocin-induced diabetes, fasting blood glucose, insulin, total cholesterol, body weight, rat model
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
