Porphyromonas gingivalis Periodontal Infection and Its Putative Links with Alzheimer’s Disease
Singhrao, Sim K., Harding, Alice, Poole, Sophie, Kesavalu, Lakshmyya, Crean, StJohn·2015·Mediators of Inflammation
Cited by (195)
Items 101–195 of 195
- Effects of Oral Commensal Streptococci on Porphyromonas gingivalis Invasion into Oral Epithelial CellsAlyssa Hanel, Hannah M. Herzog, Michelle G. James, Giancarlo A. Cuadra · 2020 · Dentistry Journal
- Don’t forget the exogenous microbial transglutaminases: it is immunogenic and potentially pathogenicAaron Lerner, Torsten Matthias · 2016 · AIMS Biophysics
- Secondary Production of the Intertidal Macrofauna of Prainha Beach, BrazilRicardo S. Cardoso, Valéria Gomes Veloso · 2003 · Dialnet (Universidad de la Rioja)
- Gastrointestinal Changes and Alzheimer's DiseaseMona Sohrabi, Bijayani Sahu, Harpreet Kaur, Wendie A. Hasler, Atish Kumar Prakash, Colin Kelly Combs · 2022 · Current Alzheimer Research
- Interaction Between Autophagy and Porphyromonas gingivalis-Induced InflammationSen Kang, Anna Dai, Huiming Wang, Pei‐Hui Ding · 2022 · Frontiers in Cellular and Infection Microbiology
- Broadening Horizons: Exploring the Cathepsin Family as Therapeutic Targets for Alzheimer's DiseaseXiaohui Liu, Xiaotong Liu, Yue Wu, Shuang Li, Kaidi Ren, Meng Cheng, Bing Huang, Yang Yang, Peipei Liu · 2024 · Aging and Disease
- Chronic Periodontitis and Alzheimer Disease: A Putative Link of Serum Proteins Identification by 2D-DIGE ProteomicsXianfang Rong, Liping Xiang, Yanfen Li, Hongfa Yang, Weijian Chen, Lei Li, Defeng Liang, Xincai Zhou · 2020 · Frontiers in Aging Neuroscience
- Long non‑coding RNAs are novel players in oral inflammatory disorders, potentially premalignant oral epithelial lesions and oral squamous cell carcinoma (Review)Kaiying Zhang, Wei Qiu, Buling Wu, Fuchun Fang · 2020 · International Journal of Molecular Medicine
- An Association of Pathogens and Biofilms with Alzheimer’s DiseaseChakravarthi, Sandhya T., Joshi, Suresh G. · 2021 · Microorganisms
- Lipidome of the Bacteroides Genus Containing New Peptidolipid and Sphingolipid Families Revealed by Multiple-Stage Mass SpectrometryCheryl Frankfater, Mariana Gabriela Sartorio, Ezequiel Valguarnera, Mario F. Feldman, Fong‐Fu Hsu · 2023 · Biochemistry
- Hemophore-like proteins of the HmuY family in the oral and gut microbiome: unraveling the mystery of their evolutionTeresa Olczak, Michał Śmiga, S.V. Antonyuk, John W. Smalley · 2024 · Microbiology and Molecular Biology Reviews
- Proteus mirabilis Targets Atherosclerosis Plaques in Human Coronary Arteries via DC-SIGN (CD209)Ying Xue, Qiao Li, Chae Gyu Park, John David Klena, Andrey P. Anisimov, Ziyong Sun, Wei Xiang, Tie Chen · 2021 · Frontiers in Immunology
- A review of the roles of pathogens in Alzheimer’s diseaseMeng Zhao, Yongchun Wang, Yanxin Shen, Chunxiao Wei, Guimei Zhang, Li Sun · 2024 · Frontiers in Neuroscience
- Crystal structure of Type IX secretion system PorE C-terminal domain from Porphyromonas gingivalis in complex with a peptidoglycan fragmentNhung Thi Trang Trinh, Hieu Quang Tran, Quyen Van Dong, Christian Cambillau, Alain Roussel, Philippe Leone · 2020 · Scientific Reports
- Modeling of the brain-lung axis using organoids in traumatic brain injury: an updated reviewJong-Tae Kim, Kang Song, Sung Woo Han, Dong Hyuk Youn, Harry Jung, Keun‐Suh Kim, Hyo‐Jung Lee, Ji Young Hong, Yong-Jun Cho, Sung‐Min Kang et al. · 2024 · Cell & Bioscience
- Oral microbiota in oropharyngeal cancers: Friend or foe?Riccardo Nocini, Lorenzo Lo Muzio, Davide Gibellini, Giovanni Malerba, Michele Stanislaw Milella, Salvatore Chirumbolo, Nicoletta Zerman · 2022 · Frontiers in Oncology
- Toll-like receptor agonists Porphyromonas gingivalis LPS and CpG differentially regulate IL-10 competency and frequencies of mouse B10 cellsZhiqiang Liu, Yang Hu, Pei YU, Lin Mei, Grace Huang, Toshihisa Kawai, Martin A. Taubman, Zuomin Wang, Xiaozhe Han · 2017 · Journal of Applied Oral Science
- Biomarkers for detection, prognosis and therapeutic assessment of neurological disordersSarita G. Singh, Sunil Kumar Gupta, Prahlad Kishore Seth · 2018 · Reviews in the Neurosciences
- Studying ancient human oral microbiomes could yield insights into the evolutionary history of noncommunicable diseasesAbigail Shahar Gancz, Laura Susan Weyrich · 2023 · F1000Research
- The oral organ: A new vision of the mouth as a whole for a gerophysiological approach to healthy agingChiara Cecchin-Albertoni, Olivier Deny, Valérie Planat‐Benard, Christophe Guissard, Jenny Paupert, Frédéric Vaysse, Mathieu Marty, Louis Casteilla, Paul Monsarrat, Philippe Kémoun · 2024 · Ageing Research Reviews
- Periodontitis as a Risk Factor for Alzheimer’s Disease: The Experimental Journey So Far, with Hope of TherapyAlice Harding, Shalini Kanagasingam, Richard R. Welbury, Sim K. Singhrao · 2022 · Advances in experimental medicine and biology
- Structural and functional analyses of the Porphyromonas gingivalis type IX secretion system PorN proteinOlivier Fuchsbauer, Ignacio Lunar Silva, Eric Cascalès, Alain Roussel, Philippe Leone · 2022 · Journal of Biological Chemistry
- The Effects of Antimicrobial Mouthwashes on Systemic Disease: What Is the Evidence?Mohammad S. Alrashdan, Jair Carneiro Leão, Amazon Doble, Michael John McCullough, Stephen Ross Porter · 2023 · International Dental Journal
- The role of the oral microbiome, host response, and periodontal disease treatment in Alzheimer's disease: A primerJaclyn C. Chalmers, Yvonne Lorraine Kapila · 2025 · Periodontology 2000
- Can Control Infections Slow Down the Progression of Alzheimer’s Disease? Talking About the Role of Infections in Alzheimer’s DiseaseMingchao Shi, Chunrong Li, Xiaoping Tian, Fengna Chu, Jie Zhu · 2021 · Frontiers in Aging Neuroscience
- Unfolded p53 in non-neuronal cells supports bacterial etiology of Alzheimer’s diseasePeter William French · 2022 · Neural Regeneration Research
- Investigating the relationship between periodontitis and specific memory processes in the search for cognitive markers of Alzheimer’s disease riskMichał Wereszczyński, Aleksandra Śmigiel, Iwona M. Tomaszewska, Agnieszka Niedźwieńska · 2023 · Scientific Reports
- Occlusion dysfunction and Alzheimer’s disease: Mendelian randomization studyQing Wang, Wenyu Zhen, Rui Hu, Zifei Wang, Yuqiang Sun, Wansu Sun, Chunxia Huang, Jianguang Xu, Hengguo Zhang · 2024 · Frontiers in Aging Neuroscience
- A Novel Approach to the Treatment and Prevention of Alzheimer’s Disease Based on the Pathology and MicrobiologyHerbert B. Allen · 2021 · Journal of Alzheimer s Disease
- Enhanced Responsive Formation of Extracellular Traps in Macrophages Previously Exposed to Porphyromonas gingivalisYujie Liu, Jialu Chen, Zi-bo Fu, Yue Wang, Xian-zi Cao, Ying Sun · 2022 · Inflammation
- Human Herpesvirus 6A U4 Inhibits Proteasomal Degradation of the Amyloid Precursor ProteinTian Tang, Junli Jia, Emanuela Garbarino, Luyao Chen, Jingjing Ma, Peipei Li, Xiangjun Chen, Lily Wang, Yiqun Wen, Yuhang Wang et al. · 2021 · Journal of Virology
- The brain pathobiome in Alzheimer's diseaseNanda Kumar N. Shanmugam, William A. Eimer, Deepak Kumar Vijaya Kumar, Rudolph E. Tanzi · 2024 · Neurotherapeutics
- Renegade cellular and bacterial genetic sequences in monkey-derived stealth adapted virusesMartin Wj · 2019 · Journal of Human Virology & Retrovirology
- Reciprocal Interactions Between Periodontal Disease and Alzheimer’s Disease: Implications for Mutual Triggering, Exacerbation, and Treatment Interventions—A Comprehensive Review of the LiteratureShatha Gharaibeh, Alameen Alsabbah, Ahmad Alloubani, Abeer Gharaibeh · 2025 · Neurology International
- Oral Health Status and Treatment Need in Geriatric Patients with Different Degrees of Cognitive Impairment and DementiaSantosh Kumar, Prakash C. Jha, Bhupender Singh Negi, Nazia Haidry, Pranay Kulkarni, Saakshi Gulati, Jayalakshmi Muttu · 2021 · Journal of Family Medicine and Primary Care
- Characterizing the supragingival microbiome of healthy pregnant womenYangyang Zhang, Zeyu Wu, Ling Li, Xiaohe Wang, Wenxian Fan, Jin Hua Zhao · 2022 · Frontiers in Cellular and Infection Microbiology
- Preventing Oral DiseaseSusan A. Fisher‐Owens, Elizabeth Mertz · 2018 · Pediatric Clinics of North America
- Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid familiesBrian A. Kleiboeker, Cheryl Frankfater, Mary Ellen Davey, Fong‐Fu Hsu · 2023 · Journal of Lipid Research
- Changing how we think about infectious diseasesJules J. Berman · 2019 · Elsevier eBooks
- Metagenomic characterization of the microbiomes in five different body habitats of otherwise healthy individuals with periodontal diseaseSujin Oh, Hyo‐Jung Lee, Kyoung Un Park · 2023 · Frontiers in Cellular and Infection Microbiology
- Antibacterial Activity of Cissus quadrangularis (Veldt Grape) Against Porphyromonas gingivalis, a Keystone Pathogen in Periodontal Disease: An In Vitro StudyAathira R Nair, Prem Blaisie Rajula, Potluri Leela Ravishankar, Sai Sri Soury Geddam, B. S. V. V. SUBHASHINI, S. Lochini · 2024 · Cureus
- A novel microbiological medium for the growth of periodontitis associated pathogensNiall A. Hickey, Kathryn A. Whitehead, Liliana Shalamanova, Jonathan A. Butler, Rebecca L. Taylor · 2019 · Journal of Microbiological Methods
- Effect of tricyclic 1,2-thiazine derivatives in neuroinflammation induced by preincubation with lipopolysaccharide or coculturing with microglia-like cellsBenita Wiatrak, Edward Krzyżak, Berenika Marta Szczęśniak-Sięga, Marta Szandruk-Bender, Adam Szeląg, Beata Nowak · 2022 · Pharmacological Reports
- Unraveling Alzheimer’s: Exploring the Gut Microbiota–Brain Axis as a New Frontier in UnderstandingShahzada Mudasir Rashid, Rahil Razak, Aabid Khaliq Tantray, Antonisamy William James, Nuzhat Showkat, Faheem Shehjar, Fatimah Jan, Sheikh Bilal Ahmad, Andleeb Khan, Zahoor Ahmad Shah · 2024 · Journal of dementia and Alzheimer's disease
- Chronic gingivitis increases the risk of early-onset Alzheimer's diseaseDong-can Mo, Xiaoling Li, Jing He, Xiaozuo Lin, Pingkai Wang, Yinan Zeng, Xiaoju Wu, LiuYu Liu, Li Chi, Man Luo · 2025 · Journal of Alzheimer s Disease
- Predicted economic damage from a quick, simple Alzheimer's disease cureLeslie C. Norins · 2019 · Medical Hypotheses
- Prevalence of Periodontal Disease among Patients at the Outpatient Clinic of Internal Medicine in an Academic Hospital in The Netherlands: A Cross-Sectional Pilot StudyThomas J. T. Leung, Nina Nijland, Victor E. A. Gerdes, Bruno G. Loos · 2022 · Journal of Clinical Medicine
- The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's diseaseAnnelise E. Barron, Jennifer S Lin, Mark I. Ryder, Peter N. Bergman · 2025 · Journal of Internal Medicine
- Bacteremia Prevention during Periodontal Treatment—An In Vivo Feasibility StudyPatrick Jansen, Georg Conrads, Johannes-Simon Wenzler, Felix Krause, Andreas Braun · 2023 · Antibiotics
- Exploring the Link Between Periodontitis and Alzheimer’s Disease—Could a Nanoparticulate Vaccine Break It?André Ferreira da Silva, Alexandra Gomes, Lídia Gonçalves, Adelaide Maria Afonso Fernandes, António José Almeida · 2025 · Pharmaceutics
- Periodontitis determining the onset and progression of Huntington's disease: review of the literatureMaría de Lourdes Rodríguez Coyago, Victoria Emilia Sánchez Temiño · 2015 · Medwave
- In vitro modulation of proinflammatory and proteolytic activities of Porphyromonas gingivalis by selected lactobacilliJohana Romina Naja, Leyla Desparois, Elvira Maria Hebert, Marı́a Elena Nader-Macı́as, Lucila Saavedra, Carlos Javier Minahk, Vanessa P. Houde · 2025 · Journal of Oral Microbiology
- The use of non-steroidal anti-inflammatory drugs (NSAIDs) in clinical practice for the treatment of periodontitis: a narrative reviewAnna Zając, Magdalena Kuznik, Marta Penno, Anna Czopek, Justyna U. Miszczyk · 2024 · Current Issues in Pharmacy and Medical Sciences
- V-ATPase and Lysosomal Energy Sensing in Periodontitis and Medicine-Related Osteonecrosis of the JawXianrui Yang, Lexie Shannon Holliday · 2025 · Biomolecules
- Some South African medicinal plants associated with oral health care: Their phytochemical constituents and involvement in biological activitiesSemakaleng Mpai, Ashwell Rungano Ndhlala, Mulanga Luscious Mulaudzi, Peter Masoko · 2025 · South African Journal of Botany
- Infection of Porphyromonas gingivalis in Alzheimer’s Disease and the Suppression of ImmunityCitra Feriana Putri, Endang Winiati Bachtiar · 2021 · Dental Hypotheses
- Structure–function analysis of PorXFj, the PorX homolog from Flavobacterium johnsioniae, suggests a role of the CheY-like domain in type IX secretion motor activityMariotte Zammit, Julia Bartoli, Christine Kellenberger, Pauline Melani, Alain Roussel, Eric Cascalès, Philippe Leone · 2024 · Scientific Reports
- The Role of Periodontitis in Increasing Cognitive Decline in Alzheimer\'s DiseaseClaudia M. Tellez Freitas, Shankargouda Patil, Nomikos Klonaris, Josue D. Gonzalez Murcia · 2025 · The Journal of Contemporary Dental Practice
- Analysis of the proliferation-inhibiting active components against periodontal pathogenic bacteria contained in fig leaf extractTomoya Fujii, Ayaka Yazawa, Takeshi Isobe, Kiwa Kitada, Yuichiro Takai, Yinjie Yu, Shigeki Kamitani · 2026 · FEMS Microbiology Letters
- Tooth loss and dementia amongst older adults residing in long‐term care facilities in Vancouver: A case‐control studyJoon‐Ho Yoon, Nicholas Tong, Chris C. L. Wyatt · 2023 · Gerodontology
- Folate mediates cognitive impairment of aged people with periodontitisFei Liu, Yajing Liu, Yuheng Feng, Jiashuo Zhao, Muyun Wang, Minghan Ye, Yanyan Zhang, Xueqi Gan, Qing Pan, Jiefei Shen · 2025 · Nutritional Neuroscience
- Is Alzheimer's Disease Infectious? Relative to the CJD Bacterial Infection Model of NeurodegenerationFrank O. Bastian · 2015 · AIMS neuroscience
- [Developments in Research on the Relationship Between Porphyromonas gingivalis and Non-Oral Diseases].Ke-Ke Zhang, Yan Ping Sun, Yihuai Pan · 2023 · PubMed Central
- Development of a Simple Protocol for Zymogram-Based Isolation and Characterization of Gingipains from Porphyromonas gingivalis: The Causative Agent of PeriodontitisEng Sze Wei, Ramasamy Kavitha, Mohammad Auwal Sa’ad, Pattabhiraman Lalitha, Neeraj Kumar Fuloria, Manickam Ravichandran, Shivkanya Fuloria · 2023 · Applied Sciences
- Anatomical, Biological, and Surgical Features of Basal GangliaNüket Göçmen Mas, Harun Muayad Said, Murat Tosun, Nilufer Yonguc, Yasemin Dilek Soysal, Hamit Selim Karabekir · 2017 · InTech eBooks
- Mind Your Mouth: Impact of Oral Bacteria on Alzheimer's DiseaseAli I. Mohammed, Ahmed I. Mohammed, Eric Charles Reynolds · 2025 · Journal of Oral Pathology and Medicine
- Antibiofilm activity of lichen secondary metabolitesAlaa Sweidan · 2017
- Linking periodontitis and Alzheimer’s disease: systemic inflammation as a shared mechanismClaudio Cesari, Giada Belleri, Simone Fabrizi, Francesca Zangari · 2025 · Academia molecular biology and genomics.
- E-cigarette liquids alter the biogenesis and properties of Aggregatibacter actinomycetemcomitans outer membrane vesiclesMahsa Khodabakhsh Majd, Lillian Y. Wu, Giancarlo A. Cuadra, Angela C. Brown · 2026 · Frontiers in Cellular and Infection Microbiology
- Oral Microbiota: Findings, Classification, Clinical Significance, and Therapeutic Interventions for Human Systemic DiseasesMiao Zhang, Meng Du, Wenjiang Zhang, Renhuan Huang, Wanting Li, Tongqi Li, Junping Bai, Ning Zhang, Jungang Chen, Jing Zhou et al. · 2026 · iMetaMed
- Association Between Oral Malodor and Dementia: An 11-Year Follow-Up Study in JapanDuc Sy Minh Ho, Takashi Zaitsu, Hikaru Ihira, Masanori Iwasaki, Akihiro Yoshihara, Seitarô Suzuki, Manami Inoue, Kazumasa Yamagishi, Nobufumi Yasuda, Jun Aida et al. · 2024 · Journal of Alzheimer s Disease Reports
- Dementia and Oral Health: Is There A Connection?Suellan Go Yao, James Burke Fine · 2020 · Dentistry - Open Journal
- The Historical Development of the Pathological Changes in Alzheimer’s Disease Based on Microbiology, Anatomy, and PhysiologyHerbert B. Allen, Rachel A. Allen · 2022 · Medical Research Archives
- Primary Prevention of Alzheimer’s Disease (AD)Ettore Bergamini, Gabriella Cavallini · 2019 · IntechOpen eBooks
- Porphyromonas gingivalis and its impact on periodontal health and systemic diseases. A concise review.Pablo Jasma, Patricio Sánchez · 2019 · International Journal of Medical and Surgical Sciences
- A Model Of Agitated Behavioral Symptoms In Persons With Alzheimer DiseaseKatherine Kero · 2020 · Human Biology
- Oral biosciences: The annual review 2020Hayato Ohshima, Kenji Mishima, Norio Amizuka · 2021 · Journal of Oral Biosciences
- Microbial Influence on Alzheimer's DiseaseAshley Hamby · 2021 · The Cardinal Edge
- Die Bedeutung des Darm-Mikrobioms für die Alzheimer-DemenzGeorg Adler · 2022 · Nervenheilkunde
- Mulig samspill mellom genet for apolipoprotein og periodontitt ved Alzheimers sykdom og enkelte systemiske sykdommerIngar Olsen · 2016 · Den norske tannlegeforenings Tidende
- Kan oral infeksjon bidra til Alzheimers sykdom?2015 · Den norske tannlegeforenings Tidende
- Functional Relationship between Porphyromonas Gingivalis-driven Periodontal Disease and Alzheimer's DementiaKa Young Boo, Dae Sol Choi, Hye Won Gwak, Da Eun Jeon, Su Eun Kang, Min Seo Lee, Tae Young Park, Hyeon Ryong Shim, Ji Hye Lee · 2022 · 대한구강악안면병리학회지
- Research Progress in Pathogenicity and Drug Therapy of Porphyromonas gingivalis婧 高 · 2023 · Advances in Clinical Medicine
- Coinfection of Porphyromonas gingivalis and Toxoplasma gondii impairs neurocognitive function and induces anxiety-like behavior in rats: a behavioral studyHenglong Cao, Jianfeng Lin, Wanyi Wei, Jianzhao Luo, Hao Yuan, Yining Song, Kunmei Yang, Xiao Ma, Ning Song, Mei Yu · 2026 · Frontiers in Immunology
- Dietary modulation of gut microbiota and gut–brain axisSofia Viana, Carolina Ferreira, Cristiana Violante, María Dolores Hinchado, Flávio Reis · 2026 · Elsevier eBooks
- Nonsteroidal anti-inflammatory drugs as adjunctive therapy in patients with periodontitis and high caries riskTaylakova Dildora Ibragimovna, Natalia A. Sokolovich · 2026 · Pediatric dentistry and dental prophylaxis
- Awareness and Perceptions of the association between Periodontal Disease and Alzheimer’s Disease among Dental Professionals: A Cross-Sectional SurveySuvarna Vankudothu, Samhitha Dudyala, Suryakanth Malgikar, Jyotsnendu Giri, Bandi Anuja, Rajashri D. · 2026 · Journal of Indian Dental Association
- Village Forest Experience Program Improves Cognitive Function and Reduces Salivary Cortisol and Oral Pathogens in Older AdultsMu-Yeol Cho, Je-Hyun Eom, JW Kim, Yun-woo Kim, Seung‐Jo Yang, Jiyoung Hwang, Mi-Hwa No, H Hyounglyul Kim · 2026 · Healthcare
- Overview of head & neck microbiotaRD Jayasinghe, K.S.N.D. Gunawardhana, Kalpani Senevirathna · 2026 · Advances in immunology
- Comorbidity of periodontal diseases and Alzheimer’s diseaseД И Трухан, Сулимов Анатолий Филиппович, L. Yu. Trukhan, Maria Yu. Rozhkova · 2026 · Meditsinskiy sovet = Medical Council
- Periodontal disease and dementia risk: A narrative review of population-based evidence and modifiable interventionsWei-Ling Chen, Yu‐Kang Chang, Yi‐Pei Lin, Kuang‐Hsi Chang · 2026 · 童綜合醫學雜誌
- Porphyromonas gingivalis as a keystone pathogen in systemic diseasesYaniv Mayer, Daniela Matanes, Jamil Awad Shibli · 2026 · Einstein (São Paulo)
- Periodontitis and Alzheimer's disease, common pathways in down syndromeFabio Arriola‐Pacheco, Alicia Leonor Pinzón-Te, Rodrigo Serrano-Piña, Bertha Arelly Carrillo-Ávila, Jaime Díaz‐Zúñiga, Samanta Melgar‐Rodríguez, Víctor Manuel Martínez-Aguilar · 2026 · Frontiers in Dental Medicine
- From mouth to brain: Linking periodontal and peri‐implant dysbiosis to systemic inflammation and neuropathologyEmilio Alfredo Cafferata, Frank Schwarz, Jaime Díaz‐Zúñiga, Alpdoğan Kantarcı · 2026 · Periodontology 2000
- The DentoNeural Axis: A Piezo channel-mediated mechanosensory pathway linking tooth loss to cognitive declineKyung-A Oh · 2026 · Aging Brain