Recycling of Waste Streams of the Biotechnological Poly(hydroxyalkanoate) Production by Haloferax mediterranei on Whey
Open accessAbstract
For manufacturing “bioplastics” such as poly(hydroxyalkanoates) (PHA), the combination of utilization of inexpensive carbon sources with the application of robust microbial production strains is considered a decisive step to make this process more cost-efficient and sustainable. PHA production based on surplus whey from dairy industry was accomplished by the extremely halophile archaeon Haloferax mediterranei . After fermentative production of PHA-rich biomass and the subsequent cell harvest and downstream processing for PHA recovery, environmentally hazardous, highly saline residues, namely spent fermentation broth and cell debris, remain as residues. These waste streams were used for recycling experiments to assess their recyclability in subsequent production processes. It was demonstrated that spent fermentation broth can be used to replace a considerable part of fresh saline fermentation medium in subsequent production processes. In addition, 29% of the expensive yeast extract, needed as nitrogen and phosphate source for efficient cultivation of the microorganism, can be replaced by cell debris from prior cultivations. The presented study provides strategies to combine the reduction of costs for biomediated PHA production with minimizing ecological risks by recycling precarious waste streams. Overall, the presented work shall contribute to the quick economic success of these promising biomaterials.
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About 66% PHBV were produced by pure culture of Haloferax mediterranei from whey in a fed batch fermenter.
“About 66% PHBV were produced by pure culture of Haloferax mediterranei from whey in a fed batch fermenter [104]”
From Food Waste Biorefinery: Pathway towards Circular Bioeconomy (2021) · cites this paper as [104]
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Food Waste Biorefinery: Pathway towards Circular Bioeconomy
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- Authors
- Koller, M.
- Affiliations
- University of Graz (AT)
- Corresponding author
- Koller, Martin
- ORCID
- Koller, Martin
- Venue
- International Journal of Polymer Science
- Publisher
- Wiley
- Published
- 2015
- Volume
- 2015
- Pages
- 1-8
- ISSN
- 1687-9422 (ISSN-L)
- 1687-9430
- OpenAlex
- W2035721586
- Cited by
- 107
- References
- 22
- Citations by year
- 2026: 9 · 2025: 12 · 2024: 6 · 2023: 8 · 2022: 12 · 2021: 19 · 2020: 17 · 2019: 7 · 2018: 6 · 2017: 4 · 2016: 2 · 2015: 5
- FWCI
- 2.05
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- International Journal of Polymer Science (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- European Commission (GRD2-2000-30385)
- Topics
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biopolymer Synthesis and Applications
- Physical Sciences › Environmental Science › Pollution › Microbial bioremediation and biosurfactants
- Keywords
- polyhydroxyalkanoates, Haloferax mediterranei, whey, bioplastic production, cell debris, yeast extract replacement, extremely halophilic archaea, downstream processing, dairy waste
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