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Cited by 474

The DOI matches its Crossref record; 287 of the 287 references it cites were found in a registry or an index.

ROS: Basic Concepts, Sources, Cellular Signaling, and its Implications in Aging Pathways

Open access
de Almeida, Arthur José Pontes Oliveira, de Oliveira, Júlio César Pinheiro Lúcio, da Silva Pontes, Larisse Virgolino, de Souza Júnior, Javanyr Frederico, Gonçalves, Tays Amanda Felisberto, Dantas, Sabine Helena, de Almeida Feitosa, Mathania Silva, Silva, Antonia Oliveira, de Medeiros, Isac Almeida·2022·Oxidative Medicine and Cellular Longevity

Abstract

Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of molecules with oxidizing properties known as ROS. Despite those molecules being implied negatively in aging and numerous diseases, their key role in cellular signaling is evident. ROS control several biological processes such as inflammation, proliferation, and cell death. The redox signaling underlying these cellular events is one characteristic of the new generation of scientists aimed at defining the role of ROS in the cellular environment. The control of redox potential, which includes the balance of the sources of ROS and the antioxidant system, implies an important target for understanding the cells’ fate derived from redox signaling. In this review, we summarized the chemical, the redox balance, the signaling, and the implications of ROS in biological aging.

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Crossref · 10.1155/2022/1225578

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Metadata

Authors
de Almeida, A. J. P. O., de Oliveira, J. C. P. L., da Silva Pontes, L. V., de Souza Júnior, J. F., Gonçalves, T. A. F., Dantas, S. H., de Almeida Feitosa, M. S., Silva, A. O., & de Medeiros, I. A.
Venue
Oxidative Medicine and Cellular Longevity
Publisher
Wiley
Published
2022-01
Volume
2022
Issue
1
Pages
1225578-1225578
ISSN
  • 1942-0994 (ISSN-L)
  • 1942-0900
OpenAlex
W4306840935
Cited by
474
References
287
FWCI
21.06
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: ROS: Basic Concepts, Sources, Cellular Signaling, and its Implications in Aging Pathways. https://app.cochat.ai/papers/10.1155/2022/1225578
The paper
de Almeida, A. J. P. O., de Oliveira, J. C. P. L., da Silva Pontes, L. V., de Souza Júnior, J. F., Gonçalves, T. A. F., Dantas, S. H., de Almeida Feitosa, M. S., Silva, A. O., & de Medeiros, I. A. (2022). ROS: Basic Concepts, Sources, Cellular Signaling, and its Implications in Aging Pathways. Oxidative Medicine and Cellular Longevity. https://doi.org/10.1155/2022/1225578

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.